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Elevated Prolactin and DHEA-S - 27 Years Old, 182lbs

9/9/2025, 10:20:28 PMMale25-34

After nearly a year of experiencing irregular and absent menstrual cycles, I finally consulted a physician to evaluate my hormonal levels. The tests revealed elevated levels of Prolactin and DHEA-S, while other tests for insulin, cortisol, thyroid hormones, and iron returned normal results. There appears to be no ovarian issues, and I am currently awaiting the interpretation of an MRI scan of my brain, as well as kidney function results. My symptoms have worsened over time. What initially seemed to be mere sadness and depression a few months back has escalated into severe cognitive fog, a struggle to process new information, feelings of detachment, poor time management, impulsive decision-making, pelvic discomfort, frequent calf cramps, insomnia, profound tiredness, hair thinning, and most recently, evening headaches. Over the past seven years, I have faced a series of distressing life events that led me into a very dark period. During this time, I isolated myself from social interactions, engaging only with work, which resulted in a more inactive lifestyle. Could the weight of these experiences have weighed me down so heavily? Additionally, I have been intermittently using Vyvanse for the past three years, having switched to its generic form four months ago. Coincidentally, that period marked a noticeable decline in my overall well-being. I have read that Vyvanse can lower prolactin levels due to its dopamine effects, which makes me curious if anyone else has encountered a similar circumstance. I’d like to know if my experiences resonate with any of you. While I'm waiting for my test results, I am eager to explore possible diets, exercises, books, or any other suggestions that might alleviate my condition. I sincerely value any advice or shared experiences you could offer.

Thyroid DisordersEndocrinologyRheumatology

Answers (1)

Cony

9/9/2025, 10:20:49 PM

OpenHealth AI

It sounds like you're navigating a complex situation involving hormonal imbalances and significant emotional challenges, which can understandably feel overwhelming. Your elevated prolactin and DHEA-S levels, along with the various symptoms you've described, warrant careful consideration. Let's break this down into manageable pieces.

Key Points

  1. Hormonal Imbalances: Elevated prolactin can be associated with various factors, including stress, certain medications like Vyvanse, and other health issues. Elevated DHEA-S can indicate adrenal gland activity or other conditions.
  2. Emotional and Cognitive Symptoms: Your worsening cognitive fog, emotional distress, and physical discomfort can be linked to stress, hormonal changes, and possibly the effects of medication.
  3. Lifestyle Factors: Your past experiences and current lifestyle choices can significantly impact both mental and physical health.

Explanation

Hormonal imbalances can lead to a plethora of symptoms, including mood disturbances, cognitive difficulties, and physical issues like fatigue and sleep disturbances. Both prolactin and DHEA-S levels play roles in stress response and reproductive health. Stress, in turn, can raise prolactin levels further, creating a cycle that exacerbates your symptoms.

Your history of distressing life events combined with feelings of isolation and inactivity can contribute substantially to your emotional well-being. It's essential to address both the hormonal and lifestyle aspects to start feeling better.

Next Steps

  1. Monitor Symptoms: Keep a detailed journal of your symptoms, noting any patterns, triggers, or changes, which can aid in discussions with your healthcare provider.

  2. Nutrition: Consider a balanced diet rich in whole foods, including:

    • Fruits & Vegetables: Aim for a variety to ensure nutrient diversity.
    • Healthy Fats: Incorporate sources like avocados, nuts, and olive oil.
    • Lean Proteins: Focus on sources like chicken, fish, beans, and legumes.
    • Complex Carbohydrates: Whole grains can provide energy without drastic blood sugar spikes.
  3. Exercise: Gentle, regular exercise can improve mood and overall well-being. Try:

    • Walking: Start with short, enjoyable walks and gradually increase duration.
    • Yoga or Stretching: These can help reduce stress and improve physical comfort.
  4. Mindfulness & Mental Health: Explore mindfulness practices or gentle mindfulness-based cognitive therapy (CBT) exercises. Resources like books or apps focused on meditation can also be beneficial.

  5. Social Support: Consider reaching out for connection with friends or support groups. Engaging socially, even in small doses, can help alleviate feelings of isolation.

  6. Stay Informed: Continue engaging with your healthcare provider about your MRI results and any emerging symptoms. Discuss whether the timing of your Vyvanse dose needs evaluation based on your recent experiences.

Conclusion

While awaiting your test results, focusing on nutrition, gentle exercise, and mindfulness can significantly impact your overall health and well-being. Remember, you're not alone in your experiences, and there are paths forward that can help alleviate your symptoms over time. If you have further questions or need clarification about specific steps, feel free to reach out!

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