Is the Tingling in My Feet a Concern After Starting Topiramate?
I recently began taking Topiramate, sometimes referred to as Topamax, to manage my migraines. Over the last few days, I have been experiencing significant tingling sensations in the soles of my feet, especially in my heels. This sensation is distinct from the typical pins and needles, as I do not experience any numbness, just an uncomfortable prickling feeling. Initially, I was prescribed 25 mg each night for a week, and I’ve now increased my dosage to 50 mg nightly. It's been under a week at this higher dose. My doctor suggested that I reach out to the clinic when I am nearing the end of my current medication supply to assess whether an increase in dosage is necessary. I suspect I might need an adjustment since I'm still enduring migraines rather frequently, although the intensity has notably decreased from what I experienced previously. I am a 31-year-old female with a medical history that includes ME/CFS, fibromyalgia, orthostatic hypotension, ADHD, migraines, IBS, depression, and anxiety. My medication regimen currently consists of Venlafaxine at 225 mg per day, Midodrine at 7.5 mg per day, Topiramate at 50 mg per day, along with Naproxen 1 g and Omeprazole 20 mg on an as-needed basis for pain relief, and Sumatriptan at 50 mg for migraine episodes. I am wondering whether the tingling in my feet will diminish as I become accustomed to Topiramate. Should I be worried about this sensation? I understand that it’s a known side effect of this medication, but it has become quite bothersome for me, and I’m trying to manage my concerns without overreacting if it’s not something serious to address.
Answers (1)

9/9/2025, 7:40:44 PM
OpenHealth AI
It's understandable to be concerned about the tingling sensations you're experiencing in your feet after starting Topiramate, especially given your medical background. Tingling, or paresthesia, can indeed be a side effect of Topiramate, particularly when starting or increasing the dosage. While this sensation is typically not serious, addressing your comfort and managing any bothersome symptoms is important.
Explanation
Topiramate can lead to various neurological side effects, including tingling sensations. This feeling might diminish as your body adjusts to the medication, but if it’s causing significant discomfort or continues after an adjustment period, it’s worth addressing. It's great that you've noticed an improvement in migraine intensity, indicating a positive response to treatment.
Next Steps
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Monitor Symptoms: Keep a log of when the tingling occurs, its severity, and how it affects your daily activities. This will help you assess if it improves over time or worsens.
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Give It Time: Since you've only recently increased your dosage, allow a couple of weeks for your body to adjust. Side effects sometimes decrease as your system adapts to the medication.
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Stay in Touch with Your Doctor: Given your ongoing migraines and the bothersome tingling, it’s essential that you communicate with your healthcare provider about both the frequency and severity of your symptoms. Discuss your comfort level regarding the tingling sensation and any adjustments needed in your treatment plan.
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Self-Management Techniques: Practice stress-reducing techniques like deep breathing, mindfulness, or gentle exercise to promote overall well-being and possibly alleviate some sensations.
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Watch for Other Symptoms: While the tingling might not be serious now, if you experience new symptoms such as severe headache, vision changes, difficulty walking, or any signs of an allergic reaction (like swelling or hives), reach out to a healthcare provider promptly.
Your concerns are valid, and it's crucial to prioritize your comfort and mental well-being. Please continue to track your symptoms and maintain open communication with your medical team for the best overall management.
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