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The Impact of PDE-5 Inhibitors and Beetroot Juice on Hearing

9/8/2025, 5:30:34 PMMale25-34

A user reported experiencing tinnitus after occasionally using sildenafil, a PDE-5 inhibitor, raising questions about the potential effects of beetroot juice on hearing health. Although this inquiry may seem somewhat broad, it seeks to understand whether beetroot juice might also be ototoxic, or conversely, if it is indeed safe and why that is the case. From what I gather, both sildenafil and beetroot juice have the capacity to boost nitric oxide levels, which in turn can enhance blood circulation. It's known that the cochlea is especially sensitive to variations in blood flow, potentially leading to harm. PDE-5 inhibitors are frequently discussed in relation to ototoxicity, yet sources on the internet generally indicate that beetroot juice does not possess ototoxic properties. Could there be other factors at play, or might beetroot juice and other natural nitric oxide boosters actually be ototoxic as well? I am trying to determine whether beetroot juice represents a safer—albeit less potent—alternative to conventional PDE-5 inhibitors.

Crohn's DiseaseCOPDEndocrinology

Answers (1)

Cony

9/8/2025, 5:30:52 PM

OpenHealth AI

The inquiry about the effects of sildenafil and beetroot juice on hearing health is important and nuanced. While there are raised concerns about potential ototoxicity related to PDE-5 inhibitors like sildenafil, research suggests that beetroot juice does not typically exhibit such properties and is generally considered safe for hearing.

Explanation

PDE-5 inhibitors, such as sildenafil, can impact blood flow and are linked to tinnitus in some individuals. Tinnitus can arise from various factors, including changes in blood flow or ear function. While sildenafil may cause or exacerbate tinnitus for some individuals due to its effects on circulating nitric oxide levels and vascular dynamics, it is essential to note that this does not apply universally and depends on individual reactions.

Beetroot juice, on the other hand, is rich in nitrates, which your body converts into nitric oxide. This compound can improve circulation but, unlike PDE-5 inhibitors, there is no substantial evidence suggesting that beetroot juice is ototoxic or causes hearing issues. The cochlea may be sensitive to blood flow changes, but beetroot juice is typically safe and often recommended for its health benefits.

Next Steps

  1. Monitor Symptoms: If you're experiencing tinnitus, track when it occurs in relation to your consumption of sildenafil and beetroot juice. This may help to identify patterns or triggers.

  2. Hydration and Diet: Continue consuming beetroot juice as part of a balanced diet but pay attention to how your body responds. It's a good source of antioxidants and may provide cardiovascular benefits without adverse effects on hearing.

  3. Limit PDE-5 Inhibitors: If you've noticed tinnitus worsening with sildenafil use, consider reducing frequency or dosage, and observe changes in your symptoms.

  4. Discuss Symptoms: Should the tinnitus persist or worsen, even with dietary adjustments, consider discussing your symptoms with a healthcare professional who can provide tailored guidance and explore further investigations.

Be vigilant about your hearing health and how it responds to dietary changes. Actions towards maintaining a healthy lifestyle while monitoring any unwanted side effects are crucial. Feel free to reach out for further advice!

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