Managing Bipolar II with Mixed Features and Co-occurring Alcohol Use Disorder
Greetings to all. I'm a 44-year-old male, standing at 6 feet 1 inch and weighing 240 pounds. I am seeking advice on effective first-line treatment options for someone diagnosed with Bipolar II, particularly when mixed features are involved, alongside a history of significant Alcohol Use Disorder. Although I have successfully maintained control over my alcoholism for the past two years, I feel that I may have already sustained considerable harm. Currently, I am experiencing Post-Acute Withdrawal Syndrome (PAWS). I would like to know if there are any medication regimens that could assist in re-establishing neurochemical balance and stability for someone with a background of severe alcohol dependency and mixed Bipolar II disorder. At present, my treatment consists of a combination of Seroquel and Ativan, which has brought me the closest to achieving consistent stability. However, I suspect my psychiatrist may not fully recognize the extent of the damage inflicted during my periods of heavy drinking.
Answers (1)

9/8/2025, 3:40:34 AM
OpenHealth AI
It’s great to hear that you've achieved stability in your recovery from alcohol dependence. Managing Bipolar II with mixed features alongside a history of alcohol use disorder can indeed be challenging, but there are treatment options that may help you restore balance.
Main Points:
- Medications like mood stabilizers or atypical antipsychotics are often options for managing Bipolar II.
- It's essential that any treatment plan considers your history of alcohol use and potential PAWS.
- Additional therapy and lifestyle changes can greatly support medication.
Explanation: Bipolar II disorder, especially with mixed features, requires careful consideration when choosing medications. The goal is to stabilize mood and minimize the risk of relapse into alcohol use. Given your current use of Seroquel (an atypical antipsychotic) and Ativan (a benzodiazepine), it's wise to discuss ongoing management with your psychiatrist, which can include reassessing your medications.
For someone in your situation, there are first-line medications that might be considered:
- Mood Stabilizers: Lithium or lamotrigine can be effective for mood stabilization in Bipolar II.
- Atypical Antipsychotics: Medications like lurasidone or olanzapine can help manage mixed features without a high risk of misuse, especially considering your history of alcohol use.
It's crucial that both your current medications and any possible new additions are monitored closely for effectiveness and side effects since your past alcohol use could influence how you metabolize these drugs.
Next Steps:
- Monitor Symptoms: Keep a daily journal of your mood, sleep patterns, and any substance cravings. This will help you identify patterns and shares them with your psychiatrist.
- Discuss Medication Options: Schedule a discussion with your psychiatrist about possibly adjusting your medications to include a mood stabilizer or switching from Ativan to a safer alternative for anxiety, like buspirone, which has a lower abuse potential.
- Consider Therapy: Engage in cognitive behavioral therapy (CBT) or a support group tailored for those with co-occurring disorders. These can provide additional coping strategies and support.
- Focus on Nutrition and Exercise: Maintain a balanced diet and consider regular physical activity, as these can greatly improve mood stability and overall health.
Your proactive approach toward your health is commendable, and openly communicating with your healthcare provider will help ensure you receive safe and effective treatment tailored to your unique needs.
Related Questions
Could This Be Delayed Postherpetic Neuralgia?
I’m a 33-year-old male experiencing a range of discomforts including sharp, dull, and burning sensations radiating from my lower left back, extending to my hip and buttocks, and occasionally shooting down to my groin or leg. This has fluctuated for over two years. At 17, I contracted shingles, during which the rash and pain affected areas that are now experiencing these symptoms. I don’t remember the specifics of the treatment I received, but it likely involved antiviral medication or steroids along with pain relief options for about six weeks. The doctors were surprised by the severity of my condition at such a young age. A few years post-shingles, I developed psoriasis; however, none of the plaques are located near the painful areas, and I haven’t had a shingles outbreak since then, to my knowledge. About a year ago, I consulted a urologist who performed a CT scan with contrast, an ultrasound, blood tests, and a urinalysis, but all results were unremarkable. Six months back, my general practitioner conducted similar tests, and once again, everything came back normal. Recently, I’ve started visiting a chiropractor and a massage therapist, which has occasionally alleviated my discomfort. I also incorporate a baseball for self-massage, mobility exercises, and yoga twice a week into my routine. Could this pain be attributed to delayed Postherpetic Neuralgia or nerve damage from the shingles infection I experienced 15 years ago? I’m reaching out because I’ve been perplexed by this issue and am yearning for some relief. Over-the-counter medications like Ibuprofen, Tylenol, and Lidocaine barely make a dent in my pain, and since I’m recovering from Substance Use Disorder and alcoholism (celebrating over ten years of sobriety), I avoid opiates. This persistent pain is becoming a significant nuisance, affecting my mobility—simple tasks like walking my dog feel daunting. If there’s a chance this is something I should discuss with a neurologist, I’d like to explore that option first. Thank you for your assistance!
Concern Regarding Blood in Semen at Age 26
I am experiencing an issue where there appears to be blood in my semen. I am a 26-year-old male, 168 cm tall and weigh 74 kilograms. Let me explain the situation in detail. Last Thursday and Friday, I was engaging in edging. During the sessions, I approached the point of climax but managed to refrain from finishing. By Friday evening, I started suffering from intense pain in my lower back, coupled with a headache. I took some aspirin, which alleviated both my back pain and headache. On Saturday, I attempted edging again, but by the afternoon, I found it impossible to continue without releasing. To my shock, the semen I produced was tinged with a light pink color, which sent me into a panic—I started sweating profusely and felt faint. Later that night, I decided to masturbate again to see if the blood was still present. Initially, the semen appeared clear, but then it turned slightly pink, and the last bit looked as if blood was dripping. Today, I tried masturbating once more; it started clear but, toward the end, I noticed actual drops of blood. Additionally, I've been having trouble falling asleep for the past six months. Recently, I’ve also noticed painful lumps in my armpits. I am extremely worried about this situation and feel uncertain about what steps to take next. P.S. I created this account solely to seek help regarding this matter.
Persistent Neck Pain Five Months After Choking Incident?
I’m a 40-year-old woman, and I have been grappling with chronic neck pain for the past five months since my estranged husband assaulted me by strangulation. This wasn’t an isolated incident; it has happened before. Ever since that event, I've experienced a peculiar sensation of something 'rolling' in my neck, accompanied by discomfort whenever I attempt to turn my head to the sides. It often feels as if there's pressure against my windpipe, creating a snapping or popping sound each time I move my neck. The constant sensation is akin to having my neck feel "full" and the pain is relentless. My recent doctor examined me and conducted an x-ray, which showed no abnormalities, leaving him puzzled about the source of my discomfort. Unfortunately, he didn’t explore further options and shifted the discussion to my gallbladder, which has gallstones. His demeanor has often felt rushed, making me feel like I wasn't given ample time to voice my concerns. Currently, I can't afford to consult another physician for a second opinion. What could be the underlying issue with my neck? Given that the x-ray results were normal, should I still be concerned?
Understanding Low White Blood Cell Counts
Age 37, Caucasian male. For just over two years now, I have been undergoing testosterone replacement therapy (TRT), which necessitates regular blood tests approximately every three months. A continual finding from these tests is that my white blood cell (WBC) count consistently falls beneath the standard reference range, typically measuring around 3.3 to 3.4. A similar pattern is observed with my platelet levels. Medical professionals have indicated that as long as I am feeling well, this might simply reflect my normal baseline. In my latest blood test results, my WBC count dropped to 3.0, with platelets also reported below the reference range. Upon reviewing previous laboratory results from annual evaluations, I realized that prior to 2019, my counts had been significantly higher, usually in the mid-6 range. Notably, from the year 2018 to 2020, my WBC count has nearly halved and has remained stable at this lower level for approximately five years. This situation raises questions for me regarding whether it warrants further investigation, specifically whether I should consult a hematologist. I can definitely observe that I experience illnesses more frequently than I did in my twenties; however, apart from the low WBC and platelet counts, I generally feel healthy in my everyday life, without any alarming symptoms to report.
Strange Line Near My Eye?
I’m a 25-year-old and recently observed a peculiar line near the outer corner of my eye this past Friday evening. It hasn’t disappeared since then, and I hadn’t seen it before that moment. Thankfully, it’s not causing me any pain or disrupting my vision. Does anyone have any insight into what could be going on? I would greatly appreciate any advice or suggestions. Thank you!