Persistent Groin Discomfort and Infected Lymph Node Concerns [M22]
Greetings everyone, nearly two years ago I discovered a swollen lymph node in my groin area. Since that time, I have repeatedly consulted with my physician. An ultrasound was performed, indicating it to be nonspecific inguinal adenopathy. Further investigations, including semen and urine cultures, revealed the following: 1. Corynebacterium glucuronolyticum-seminale (2023) 2. Actinomyces urogenitalis at 10,000 CFU/mL (2023) Following the identification of these bacteria, I was treated with antibiotics and underwent additional testing: 3. Escherichia coli (BLEE+) noted at >1,000,000 CFU/mL (2024) This strain proved to be highly resistant, but after another course of antibiotics, a subsequent test showed: 4. Escherichia coli measured at 10,000 CFU/mL (2025) This variant exhibited greater susceptibility to antibiotic treatment. Despite these interventions, I am still experiencing substantial discomfort, characterized by persistent pain in my groin and my right testicle, alongside the swollen lymph node, which hasn't changed in size. Do you believe these infections could be responsible for my ongoing symptoms? I must admit, I feel quite anxious and frustrated; despite my tendency to worry excessively about my health, I have actively sought medical help throughout this ordeal. It’s disheartening to feel like no answers are forthcoming. I appreciate any thoughts or advice you might have. Thank you!
Answers (1)

9/7/2025, 1:40:50 PM
OpenHealth AI
It's understandable to feel anxious and frustrated given your ongoing groin discomfort and the complex medical history you've outlined. Your symptoms can indeed be related to the infections you've experienced, particularly considering the persistence of your pain and swollen lymph node. Let's address your concerns clearly and offer some actionable steps.
Key Points
- Infection Connection: The bacteria identified in your tests, including the resistant strain of E. coli, can contribute to ongoing symptoms, especially if they lead to inflammation or complications.
- Persistent Symptoms: Ongoing groin pain and lymph node swelling may also suggest chronic inflammation or another underlying issue that needs to be further clarified.
Explanation
The bacteria you've reported, particularly E. coli in high numbers, can be associated with infections that might linger if not fully resolved. Since you've been treated with antibiotics, it's critical to follow up on your symptoms. The persistence of the swollen lymph node and groin discomfort suggests that there may still be an infection or additional factors contributing to your symptoms.
Next Steps
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Symptom Monitoring: Keep a detailed diary of your symptoms, noting any changes in pain intensity, new symptoms, or patterns (such as after specific activities or times of day).
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Lifestyle Adjustments:
- Practice good hygiene, particularly around the groin area, to avoid further irritation or infection.
- Consider dietary changes that promote gut health, which may assist in managing bacterial levels.
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Pain Management:
- Over-the-counter pain relief (like ibuprofen or acetaminophen) may help reduce discomfort. Always follow the recommended dosages on the packaging.
- Applying warm compresses to the area may alleviate pain and discomfort.
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Follow-Up with Healthcare Provider: Given the complexity of your case, maintain regular communication with your healthcare provider. Discuss your ongoing symptoms and express your concerns about what might be causing the persistent discomfort, and inquire about possible referrals to specialists (like a urologist) for further investigation.
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Stay Informed and Supported: Consider joining a support group or forum where others with similar experiences share their journeys. This can provide both emotional support and practical advice.
It's crucial to take your symptoms seriously, and your proactive approach in seeking help is commendable. Monitoring your symptoms and keeping your healthcare provider informed will pave the way for a clearer understanding and eventual resolution. I'm here if you have further questions or need emotional support.
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