Could Post-Recovery Muscle Pain Be Linked to Serotonin Syndrome and Seizures?
I'm an 18-year-old struggling with anorexia and depression. Recently, I accidentally took an overdose of Zoloft and Lexapro, which caught my mother off guard. One moment I was engaged in conversation with her, and the next, I found myself being transported in an ambulance. I ended up in the ICU, where they worked to cool my body down with ice packs as my temperature reached approximately 38.6°C. Two days post-incident, I resumed taking only one of the SSRI medications and began experiencing visual and auditory hallucinations, though I did not show any symptoms of serotonin syndrome. However, during this time, I noticed that all of my muscles started to feel increasingly sore and painful. It’s been around ten days since that initial episode, yet the discomfort has gradually intensified. I have very little recollection of the moments leading to my unconsciousness; my mother described it as me suddenly jerking my head back and rolling my eyes upwards before collapsing, my limbs stiffening while my body exhibited spasms. She mentioned that she had to slap my face for me to regain consciousness, a moment I don’t remember. Could this episode have been a generalized tonic-clonic seizure (GTCS)? I've come across information suggesting that such symptoms could signify a severe case of serotonin syndrome, which might result in ongoing muscle pain even after the crisis has passed. I am eager to understand what might be causing this pain and if there's a way to alleviate it. Thank you for any insights! (I apologize for my poor English.)
Answers (1)

9/3/2025, 6:40:51 PM
OpenHealth AI
I'm really sorry to hear about what you've been going through. It's important to address your concerns about the muscle pain and potential links to your recent overdose and symptoms.
Key Points:
- Your muscle pain may be linked to several factors, including the medications you were taking, the recent seizure-like activity, and the stress from your hospitalization.
- It is crucial to monitor your symptoms and seek appropriate support to manage your mental health and recovery.
Explanation:
-
Muscle Pain: It’s not uncommon to experience muscle soreness after a significant medical episode, especially following seizures or muscle spasms. The medications you're on can also cause side effects that might contribute to muscle pain. While serotonin syndrome can cause a range of symptoms including muscle rigidity, you mentioned that you haven't shown symptoms consistent with it.
-
Seizure-like Activity: Based on your description, it’s possible that you experienced a generalized tonic-clonic seizure (GTCS). This type of seizure can cause muscle stiffness and jerking movements, which may lead to muscle soreness afterward.
Next Steps:
-
Monitor Symptoms: Keep a daily record of your symptoms, including muscle pain intensity, any new symptoms, and your mental health status. This information could be helpful for healthcare professionals in understanding your condition better.
-
Stay Hydrated and Rest: Ensuring you are well-hydrated and getting enough rest can aid recovery. Gentle stretching or light exercise can also help ease muscle soreness but listen to your body and avoid anything that worsens the pain.
-
Talk to Someone: Connect with a trusted family member or friend who can support you as you navigate these feelings and physiological changes. It’s essential to have someone who understands your situation.
-
Consult Your Healthcare Provider: Given your recent overdose and the experience of hallucinations, it’s crucial to discuss these symptoms with your healthcare provider. They can assess the muscle pain more comprehensively, determine if it's linked to the medications or other factors, and develop a tailored approach for your recovery.
Please remember that you’re not alone in this, and reaching out for help is a strong step towards healing. Let me know if there's anything else you need!
Related Questions
Experiencing Hallucinations on Prednisone
During a period of distress, I developed a bizarre rash on my back, unlike anything I'd encountered before. Unsure of its origin, I captured a photo and sent it to my physician. She recommended a topical ointment, which unfortunately didn’t alleviate my discomfort. After reaching out again, she prescribed a week-long course of prednisone, a medication I had never taken prior. As someone who usually researches new prescriptions—considering my regimen includes antidepressants, medication for blood pressure, thyroid supplements, and occasionally things for anxiety or sleep—I quickly looked into prednisone. My heart sank when I noticed "insomnia" on the list of potential side effects, as that was already a prevalent issue for me. Taking the first dose, I found myself sleeping soundly for nearly 48 hours. I woke up to what I thought was the television playing in another room, only to discover that it wasn't turned on. I could distinctly hear a deep male voice reminiscent of vintage news broadcasts, perhaps like Walter Cronkite, but there was no one present. I dismissed it as mere building noises. Little did I know, this was the onset of my auditory hallucinations. Soon after, visual hallucinations began to take hold. Although I can’t precisely recall the sequence of what I saw, several moments stand out: In my bedroom, there are French doors with curtains that suddenly began to sway without any apparent cause. I searched for drafts or anything that could explain the movement, but found nothing. The curtains continued to billow for several days. At one point, I perceived a shoe lodged behind the sofa, which transformed into the leg of a whole person trapped underneath, straining to push free. The couch itself seemed to shift. While I felt a mix of fear and absurd amusement, I called my son for help. He assured me there was nothing there, and for reasons I can’t quite grasp, I accepted that my vision was misleading. I eventually came to understand that I was indeed experiencing hallucinations. One night, after a social outing—though I should note I was driving on busy highways while experiencing difficulties steering—I made my way down the stairs leading to my condo. At the base, I noticed heavy outdoor steps that drop down to a hallway leading to a crawlspace. This area felt slightly eerie, even when sane. As I descended, something scuttled across my foot, prompting a jolt of surprise; I couldn’t see what it was. Upon reaching the bottom, I was confronted by an enormous spider web, sprawling like a badminton net and teeming with spiders the size of my hand, all scurrying about with frantic energy. I told myself, "You are hallucinating. Go ahead and touch the web to confirm it’s not there." As I approached with my hand outstretched, tiny, shadowy figures—almost like hobbits—rushed from the back of the hallway towards me. Recognizing that they weren’t real, I quickly abandoned my plan and hurried inside my condo. One evening, while inspecting my back in the mirror—possibly to check on the rash—I noticed a familiar mole near my left shoulder blade. As I reached to touch it, I mistakenly identified it as a tick that began crawling away from me, its legs clear to see. It felt distressing to think it was buried beneath my skin, leading me to irrationally start digging at it with my nails. I briefly considered fetching tweezers but continued my frantic effort, even as I recognized I was misidentifying the mole. I rummaged through a bottle to store what I believed were remnants of the tick, even going so far as to collect small fragments in a tissue. When morning came, I excitedly planned to share my findings with my son, only to discover that both the fragments and the tissue had vanished from the bottle entirely. Eventually, I woke up one morning to find that the curtains were no longer moving. This realization confirmed that the hallucinations had ceased. Over the subsequent days, I struggled to succinctly convey my experiences in an email to my doctor, overwhelmed by the task of organizing my thoughts. My son and I researched prednisone to confirm side effects, and there it was in fine print—"hallucinations"—noted as an uncommon occurrence. When I shared my vivid experiences with my doctor during a follow-up, her nonchalant reaction left me feeling rather perplexed. Did she encounter such cases often? Did she believe me? In a twist of fate, my sister, who has rheumatoid arthritis, soon mentioned her doctor was prescribing her increased doses of prednisone due to inadequate pain relief. Alarmed, I recounted my own ordeal, but she countered that she would prefer to hallucinate than endure discomfort. I couldn’t genuinely argue with that logic. Remarkably, she hasn’t reported any complications thus far, which leads me to wonder if the adverse reactions are not inherently genetic. To this day, I sometimes hear whispers of that old newscaster's voice, lingering in my mind.
Discontinuing Klonopin (clonazepam) Use
Greetings, I'm a 37-year-old female, standing at 5'5", living a lifestyle free from smoking and drinking. I struggle with schizoaffective disorder and PTSD, and my current medication regimen includes Depakote, Zyprexa, Prazosin, Topamax, Clonidine, and 0.5 mg of Klonopin as needed. Over the last 13 days, I've been taking Klonopin 0.5 mg intermittently, with daily usage for most of this time, though I have skipped it on approximately four occasions. At this juncture, I no longer wish to continue with Klonopin, as it contributes to feelings of deep depression, emotional numbness, and dissociation. I'm curious about the best approach to discontinue this medication. Would it be advisable to taper off gradually, or is it feasible to cease taking it immediately? Given that I am on antiepileptic drugs, I suspect the risk of experiencing a seizure is low. I appreciate any insights you may have. Thank you!
Understanding My Father's Blood Test Results: Lymphocytopenia and Polychromasia
Hello everyone, I’m reaching out as a worried daughter concerning my father's health. He’s undergone two routine blood tests, revealing various abnormalities: 1. **Polychromasia 1** 2. **Lymphocytopenia** 3. Neutrophils display hypersegmentation of nuclei. In his September blood analysis, the neutrophils indicated a left shift, and there were atypical lymphocytes, as well as signs of toxic granulation in his neutrophils. These findings were forwarded to the hematology department, which then requested additional tests for B12, ferritin, and folate. Fortunately, the results from August showed everything within normal limits. However, two weeks later my dad underwent another blood test, and we are currently waiting for those results. I am concerned about what all of this signifies. He has been experiencing lymphocytopenia for approximately six months now, and the film abnormalities have been evident since around April or May. Additionally, his alkaline phosphatase levels have been consistently elevated for years, yet he hasn’t had a thorough investigation of this issue. All other blood test results appear normal. What might be causing these conditions? And if the upcoming tests reveal similar abnormalities, what could this imply? ### Medical Background: - He has been on anti-arrhythmic medication (amiodarone), which led to thyrotoxicosis; however, his thyroid levels normalized after stopping the medication. - Managing acid reflux with lansoprazole. - Taking medication for blood pressure and cholesterol. Thank you for your insights!
Concerns about Blood Iron Levels and Health Indicators
Hello everyone! I’m a 28-year-old male, standing at 170 cm and weighing 60 kg (5’6", 132 lbs). I maintain an active lifestyle, do not use any substances or medications, and consume very little alcohol. **Background**: In April 2024, I experienced prolonged symptoms reminiscent of irritable bowel syndrome, such as diarrhea, mucus in stool, and inconsistent bowel movements. Despite undergoing various tests including those for inflammatory bowel disease, everything returned to normal. In August 2024, I consulted a gastroenterologist who recommended a colonoscopy and endoscopy. However, I decided to wait for the public healthcare system in Australia, where I am still in the queue but could opt to pay privately if necessary since I was managing most symptoms through dietary adjustments, only facing occasional flare-ups. **Current Situation**: In February and September 2025, I completed blood tests, both yielding similar findings. My iron studies revealed low transferrin levels and elevated ferritin levels, which increased in September. Additionally, alkaline phosphatase levels were also heightened and continued to rise in September; all three markers are now exceeding the reference range by approximately 20-30%. I am conscious that my health anxiety may be exacerbating some of my IBS-like symptoms, yet I remain alarmed by the surge in ferritin and alkaline phosphatase, despite them not being drastically high. Typically, these markers can indicate liver damage or serve as potential indicators of inflammation or cancer. While I generally feel fine, my flare-ups frequently accompany nausea, headaches, and fatigue. My doctor did not emphasize my test results but agreed to a test for the HFE gene. Are there specific tests I should discuss with my physician to exclude serious conditions? If the elevated results align with a potential inflammation in the gut or cancer, should I hasten the scheduling of the colonoscopy and endoscopy? From your experience, are these raised levels a matter for concern, or could they potentially be attributed to my anxiety? Thank you for any insights!
Strong and Unusual Odor in Urine for Two Weeks – Seeking Insights
Hello everyone, (I’m a 15-year-old female) For the past couple of weeks, I've noticed a remarkably strong and unpleasant odor every time I use the restroom. (Sorry, TMI) It has a scent reminiscent of a used tampon. This began shortly after my last menstrual cycle, though I can't pinpoint the precise day it started. I’ve conducted quite a bit of research and eliminated several possibilities: - I’m well-hydrated, consuming plenty of water each day, and my urine is often quite clear, yet the smell remains. - My dietary habits haven’t experienced any significant shifts over the last few months; I haven’t introduced foods typically linked with potent urine odors (like asparagus or coffee). - I am not sexually active (I’m still a virgin), so I don’t believe it pertains to any sexually transmitted infections. - In May, I underwent a comprehensive set of tests (including checks for bacterial vaginosis, yeast infections, UTIs, etc.), and the results came back negative. Of course, new issues could have arisen since then. Here are a few additional details that might be pertinent: - My vaginal discharge appears completely normal, without any unusual smells or colors. - I've been using the Nexplanon birth control implant since March. - I take Vyvanse; I took a break from it between May and August, and resumed on the 18th of August. - During my last menstrual period, I had severe cramps (among the worst I’ve ever experienced), which occurred just before this odor emerged. - I am not experiencing any pain, burning sensations, or additional symptoms—just the odor itself. - I’ve searched to see if there's any link between Nexplanon or Vyvanse and this issue, but didn’t find clear associations. Has anyone else had a similar experience? Or does anyone have any insights into what might be happening? I find myself quite confused and increasingly anxious about this. I’m considering scheduling a visit to the doctor to discuss my concerns soon. Thank you!