Persistent Discomfort Following Biopsy Procedure
I am a 28-year-old Caucasian woman with a diagnosis of polycystic ovary syndrome (PCOS). My lifestyle includes no medication and occasional alcohol consumption. Recently, I have been under the care of a fertility expert, and after undergoing a uterine biopsy, I was diagnosed with endometritis. Following the diagnosis, I began the prescribed treatment and subsequently had a follow-up biopsy two weeks ago. From my experience, both biopsy procedures were quite painful. I took the advised dosage of Advil 45 minutes prior to both appointments to alleviate some discomfort. Since then, I’ve been experiencing moderate cramping and pain in the lower pelvic region, focused around the uterus. Instead of sharp pain like during the initial biopsy, the sensation now feels more like a dull ache that is constant throughout the day. Attempting to be intimate with my partner yesterday exacerbated the discomfort significantly. Fortunately, I haven’t experienced any bleeding or fever, and while the pain is tolerable, it resembles menstrual cramps but feels distinctly different. My menstrual cycles typically range from 40 to 60 days, and since I’m neither close to ovulation nor nearing the end of my cycle, I am confident this isn’t related to my menstrual cycle. My next appointment with the specialist isn't for a few weeks. I’m wondering if this ongoing cramping is a common occurrence or if it necessitates further medical attention?
Answers (1)

9/3/2025, 3:11:07 AM
OpenHealth AI
I'm sorry to hear that you are experiencing discomfort after your recent biopsies. It's understandable to be concerned about ongoing pain, especially when combined with your recent diagnosis and treatments.
After a uterine biopsy, it's not uncommon to feel some cramping or discomfort, as the procedure can irritate the uterus. Your description of the pain as a dull ache that resembles menstrual cramps is consistent with typical post-procedure recovery. However, the fact that the discomfort has persisted and increased during intimacy suggests you should monitor your symptoms closely.
Key Points:
- Ongoing cramping after biopsy can be normal, but persistent or worsening pain does warrant attention.
- Monitor for any new symptoms such as bleeding, fever, or increased intensity of pain.
Next Steps:
-
Self-Care Measures:
- Continue to take over-the-counter pain relief (like Advil) as directed to manage your discomfort.
- Apply a heating pad to your lower abdomen for short periods to help soothe cramping.
-
Activity Modifications:
- Avoid activities that exacerbate the pain, such as vigorous exercise or intercourse, until you've assessed how you're feeling over a few days.
-
Symptom Monitoring:
- Keep a journal of your pain levels and any additional symptoms over the next week. Note if there's any change in the nature of your pain, or if you develop new symptoms.
-
Evaluate Need for Earlier Consultation:
- If the dull ache worsens, or if you experience any bleeding, fever, or unusual discharge, consider reaching out to your specialist sooner than your scheduled appointment.
It's vital to prioritize your comfort and well-being, and being attentive to any changes in your condition is important. If you have further questions or symptoms develop, don't hesitate to reach out. Take care.
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