Concerns About Iron Levels and Supplementation with High Ferritin
Hello everyone, I’m a 40-year-old male. Currently, I’m on Mounjaro for weight management, which I’ve been using for the past six months. I've successfully reduced my BMI from 35 to 27.5. For about ten years, I battled IBS and eczema, but I recently discovered that both issues stemmed from dairy proteins. After eliminating dairy from my diet, both conditions have completely improved. However, I previously dealt with chronic inflammation throughout my body. I took it upon myself to research and experiment with various solutions, as the conventional treatments I received from doctors—mostly ineffective medications and steroid ointments for my eczema—didn’t help. In mid-July, I ended up in the emergency department due to food poisoning, leading to a rapid weight loss of 5 kg within two days caused by vomiting and diarrhea. They ran some blood tests for the first time, which included measuring my iron levels. Fortunately, they provided intravenous fluids for rehydration but did not address the iron issues immediately. Here are the results from that test: - Iron: 43 - Iron binding capacity: 294 - Transferrin saturation: 14.5 - Transferrin: 2.1 - Ferritin: 325 - Vitamin B12: 349 - Folic acid: 7.7 - Hemoglobin: 18 I reviewed these results with my general practitioner yesterday during a follow-up regarding my Mounjaro treatment. Additionally, I’m currently fighting off an ear infection along with a cold. I've been prescribed two different antibiotics for the ear infection (initially staphicid and now azithromycin), along with an ointment for my outer ear. The infection was likely triggered by untreated eczema in my ear after inadvertently consuming something that contained milk powder. After reviewing my iron levels again, here’s what the recent test showed: - Iron: 45 - Transferrin: 1.96 - Iron saturation: 16 - Ferritin: 318 - Hemoglobin: 15.2 My doctor has recommended that I take iron supplements, advising a regimen of one tablet per day for 50 days, with each tablet containing 14 mg of iron along with vitamin C for enhanced absorption and folic acid. Now, I have a question: Given that my ferritin levels are already relatively high, is it wise to add more iron to my regimen? It appears I have ample iron stores, yet my body isn't releasing it effectively. Could this situation originate from the longstanding inflammation my body is still addressing? I stumbled upon the term "anemia of chronic inflammation." Is it safe to supplement with iron when my ferritin levels are elevated? I would greatly appreciate a second opinion from a healthcare professional on this matter. Thank you!
Answers (1)

8/30/2025, 10:14:19 AM
OpenHealth AI
It’s great to see you've made strides in your health, particularly with your weight management and the resolution of your IBS and eczema through dietary changes. Your current queries regarding iron levels and supplementation are important, especially given your history of inflammation and recent health issues.
Main Points:
- Your ferritin levels are indeed high, which indicates good iron stores.
- Supplementing with iron might not be necessary, especially if your body is unable to use it effectively, which can be due to chronic inflammation.
Explanation:
Ferritin is a protein that stores iron in your body, and elevated levels often indicate sufficient iron reserves. However, when you have chronic inflammation, conditions like "anemia of chronic inflammation" can occur. This condition typically results in lower iron utilization and could cause symptoms similar to anemia, despite having high ferritin levels.
Your recent blood tests indicate that while your hemoglobin levels are within the normal range, your transferrin saturation (which measures how much iron is transported in your blood) is lower than optimal. This suggests that your body might not be using the iron effectively, potentially due to inflammation or other underlying conditions.
Adding more iron supplements—even in small doses—might not be the best approach right now, especially considering your history of chronic inflammation and current health status. It’s crucial to focus on managing inflammation and overall health rather than simply addressing iron levels.
Next Steps:
-
Monitor Symptoms: Keep track of any symptoms you may experience related to fatigue, weakness, or any other changes as you manage your inflammation and infection.
-
Dietary Focus: Ensure you include foods rich in vitamin C in your diet, as it helps iron absorption from meals without needing supplements. Foods like citrus fruits, bell peppers, and broccoli can help.
-
Consultation with a Specialist: If you haven't already, consider discussing these concerns with a hematologist or a specialist in chronic inflammation. They can further evaluate whether your iron stores and levels should be monitored closely rather than supplemented.
-
Communicate with Your Doctor: If you haven’t already, express your concerns about the proposed iron supplementation regimen and your high ferritin levels to your doctor. They may reassess your need for iron supplementation, considering your comprehensive clinical picture and inflammation status.
As you navigate through this health phase, remember that your well-being is the priority, and optimizing your treatment can often take time and careful observation. Please take care of yourself, and feel free to reach out with further concerns!
Related Questions
Seeking Clarification on Blood Test Results
Hello everyone, I’m a 33-year-old female and I’ve recently been experiencing allergic reactions to certain fruits, specifically oranges, strawberries, and pears. The symptoms I've been dealing with include: - Itchiness in the throat - Discomfort during swallowing - Redness and soreness in the throat - Persistent fatigue - General malaise - A runny nose These symptoms can last several days! Recently, I had a severe reaction after consuming pears in wine, which prompted me to visit a Patient First facility. They administered an EpiPen and some form of IV medication—possibly Medrol? After evaluating my condition, they decided to call an ambulance (which I absolutely dread facing that hefty bill), where I received Benadryl along with another round of the IV medication and Pepcid. I spent about five hours there; my throat felt slightly improved, but I wasn’t completely better. They prescribed me Prednisone to take over the next three days. This incident was the most intense allergic reaction I've encountered, and the pain in my throat was substantial enough for me to seek immediate medical attention rather than waiting it out. Following the incident, I consulted with an allergist for further evaluation. Testing revealed that I’m only allergic to a couple of allergens: cats and dogs, though my reactions are relatively mild as indicated by skin tests on my arms. The doctor initially suspected I was dealing with Oral Allergy Syndrome exacerbated by my GERD, but I’m familiar with the sensation of vomit in my throat and mouth, and that didn’t match what I was feeling. Additionally, I take Pepcid twice daily, which has greatly reduced my stomach acidity issues. The allergist is now considering testing for hereditary angioedema. I have my blood test results, and a few of the readings were abnormal. Some tests may need to be redone due to difficulties in obtaining blood samples from me. I’m unable to share photos of the results here, but I can provide them in the comments if needed.
Navigating Chronic Lower Back Pain in Daily Life
Greetings! I am a 31-year-old female nurse with six years of experience in the field. Lately, I have been grappling with persistent discomfort in my lower back, specifically on both sides of my spine, which becomes noticeable after just ten minutes of walking, standing upright, or sitting. This pain is significantly disrupting my daily activities, and I often find myself spending much of my time resting in bed when I’m at home. It took a while for me to connect the dots and realize this was the issue behind my increasing need to lie down throughout the day, as I would verbalize, "I need to lie down" more frequently. While the pain is not excruciating, it certainly affects my mobility—I experience pain with every step and struggle to bend or twist. Usually, I try to push through it. To manage the discomfort, I have taken to consuming two Tylenol at the beginning of my shifts or prior to any activity lasting more than a few minutes. My loved ones have pointed out that my gait seems to suggest I am in pain. Let’s just say, it’s no surprise to me; the discomfort is a daily companion. Tylenol does provide relief, lowering the pain to about a two or three, which is a huge relief. However, there was an occasion when my mother provided me with half a tramadol. I wasn’t aware of the dosage, but it worked wonders during an outing with her and my sister when I couldn't manage to walk around the store and needed to find a place to lie down. That dose eliminated my pain entirely for roughly four to six hours. I’ve been reluctant to consult a physician about my back issues primarily due to my age. My mother was diagnosed with severe spinal stenosis recently, and years ago, she was warned in her twenties that she might become bedridden by age thirty due to an unrelated issue. Despite this foreboding prediction, she is now 65 and managing relatively well, aside from her stenosis and a case of multiple myeloma that led to a compression fracture last year. To my knowledge, my blood tests from last year were normal. At the age of 18, I sought help from an orthopedist due to hip pain radiating down to my knees, which led to physical therapy. The specialists determined that my hip socket was smaller than average and suggested that surgical intervention would be the most effective solution, a recommendation I opted not to pursue. So, I find myself wondering: should I consult a doctor regarding stronger pain relief specifically targeting my back? Are there potential solutions for alleviating my discomfort? Does it seem like I might require surgery? As of now, I do not have any imaging or diagnostics, and I have concerns about beginning opioid treatment at such a young age. :(
Is it a Stomach Virus or Food Poisoning?
I’m a 36-year-old female, weighing 52 kg and standing 173 cm tall, currently visiting Italy. Yesterday, I suspect I ingested some questionable prosciutto San Daniele, as I began to feel a slight stomach discomfort shortly after. This was the only food I consumed that my mother did not share with me. By the time I got my toddler to sleep, I noticed a headache and began to shiver; my temperature climbed to 38.6°C, leading me to take 1000 mg of paracetamol. Though I felt nauseated after dinner, I still managed to eat with a decent appetite. Today, however, I felt completely drained, experiencing extreme fatigue and nausea without any desire to eat. The only thing I could manage this afternoon was a plain cracker, but I soon had diarrhea, which seemed to be triggered by strong cooking odors wafting through the house. I’ve been experiencing intermittent stomach cramps. I can’t help but worry whether my toddler might catch this illness as well...
Inquiry About Diabetes Management in Critical Care
A 41-year-old female acquaintance of mine was recently admitted to the hospital due to Diabetic Acidosis, with a blood glucose level that dropped below 1. During her transport in the ambulance and upon arrival at the emergency room, healthcare personnel administered glucose to stabilize her condition. However, when her blood sugar rose to above 20, the junior medical staff, including the resident, opted to wait for a doctor's guidance before administering insulin. Is this a typical approach in such situations?
Does Shifting Leg Pain Indicate a Lower Risk of Blood Clots?
I’m a 23-year-old woman weighing 110 lbs and standing at 5’4". My concern regarding blood clots stems from the fact that I have been largely immobile, spending around 80-95% of my time in bed since June 2024 due to a cerebrospinal fluid (CSF) leak and awaiting surgery. Additionally, I’m on Dienogest for menstrual discomfort, which I’ve been informed may elevate the risk of clot formation. I have previously experienced superficial thrombophlebitis at an IV site, and although it felt somewhat similar, the pain was less intense. I do not have a history of deep vein thrombosis (DVT) nor a family background concerning blood clots. Typically, my international normalized ratio (INR) readings tend to be on the higher side. For daily medications, I take: 25 mg of metoprolol, 2 mg of dienogest, 400 mg of gabapentin, intermittent codeine (30 mg), 800 mg of acetaminophen, and 300 mg of caffeine. My medical diagnoses include: T11 CSF-venous fistula leading to spontaneous intracranial hypotension, hypermobile Ehlers-Danlos syndrome, and postural orthostatic tachycardia syndrome (POTS). I haven’t noticed significant color variation or swelling in either leg. Recently, I’ve been experiencing a pulsating discomfort along with tightness in a specific area of my left calf for several days. Before this, there were a few days marked by a buzzing or bubbling sensation in the same region. This morning, I noticed that while the tightness persists, the pain has diminished in my calf, but now there's a pronounced throbbing sensation at the top of my thigh, more towards the front. I am curious if this fluctuation in pain locations suggests that it’s less probable to be a serious issue. My research indicates that while blood clot-related pain can migrate, it typically does not alleviate in the original site. Unfortunately, my doctor’s office is closed until Tuesday, and I dread the thought of waiting in an urgent care or emergency room, especially since sitting exacerbates my headache.