Questions About Fasting for Autoimmune Blood Tests
Hello everyone! I'm a 30-year-old female seeking assistance from anyone who might know the answer to my query. My healthcare provider has scheduled a series of blood tests to check for autoimmune disorders, but they didn't specify whether I need to fast prior to the tests. Can anyone provide clarification on this? I really appreciate any help! The tests I am supposed to undergo include: - Complete Blood Count (CBC) - Creatinine Level - Alanine Aminotransferase (ALT) - Alkaline Phosphatase - Total Bilirubin - Antinuclear Antibody (ANA) Test - C-Reactive Protein (CRP) - Vitamin B12 Level - Thyroid-Stimulating Hormone (TSH) - Celiac Disease Panel (tTG + Total IgA) - Serum Protein Electrophoresis (SPEP)
Answers (1)

8/29/2025, 10:51:53 PM
OpenHealth AI
It's great that you're seeking clarity about fasting before your autoimmune blood tests. Here’s a straightforward breakdown:
Main Points:
- Most of the tests you listed do not require fasting.
- The exceptions and specific requirements may vary, so it’s important to clarify them.
Explanation: Fasting typically means not eating or drinking anything except water for a certain period before a blood test. Many tests, especially those related to autoimmune conditions, do not require fasting because they measure certain markers that are not significantly affected by recent food intake. However, some tests, such as the ones measuring vitamin levels or liver enzymes, can occasionally have different requirements.
For the tests you mentioned:
- Complete Blood Count (CBC): No fasting required.
- Creatinine Level: Usually, no fasting is necessary, but hydration is important.
- ALT/Alkaline Phosphatase/Total Bilirubin: Generally, no fasting, but check with your lab as sometimes fasting is preferred.
- Antinuclear Antibody (ANA) Test: No fasting required.
- C-Reactive Protein (CRP): Fasting not required.
- Vitamin B12 Level: Fasting is usually recommended for more accurate results.
- Thyroid-Stimulating Hormone (TSH): No fasting required.
- Celiac Disease Panel: No fasting required.
- Serum Protein Electrophoresis (SPEP): Generally no fasting required.
Next Steps:
- Contact Your Healthcare Provider or Lab: Confirm if you need to fast for your vitamin B12 level and if there are any specific fasting instructions for other tests based on your situation.
- Stay Hydrated: Drink water as necessary unless instructed otherwise.
- Follow Any Specific Instructions: If fasting is advised, clarify how long the fasting period should be before your appointment.
Being well-informed helps ease anxiety before your tests. If you have any more questions or concerns, feel free to ask!
Related Questions
Understanding My Symptoms: The Search for Answers
I’m a 24-year-old female who recently consulted my general practitioner regarding ongoing issues I've faced for over a decade. I experience excessively heavy menstrual cycles, requiring super plus tampons and incontinence pads as frequently as every half hour at times. In addition, I endure intense pain accompanied by nausea, and alternating bouts of diarrhea and constipation. My periods can last between 5 to 7 days, with the first couple of days rendering me completely unable to function; afterward, I manage with the help of pain relievers and a TENS machine. I have a past diagnosis of Gastritis and have also been tentatively diagnosed with Irritable Bowel Syndrome (IBS) and Crohn’s disease, though further investigation was halted when I had to switch doctors due to moving, leaving the latter not confirmed. I was sent for a transvaginal ultrasound and blood tests. The blood tests revealed I have low levels of Vitamin D and folic acid, along with a couple of other irregularities that were not explained to me, so I have been scheduled for additional tests. I had the ultrasound done earlier this week, and I am still awaiting the results. I harbor concerns that I might be suffering from endometriosis, primarily due to my symptoms. However, my question is more general in nature. After my ultrasound, the sonographer remarked that there was “nothing concerning.” While I comprehend that they may not disclose all findings immediately, their reassurance is making me ponder whether any indicators of endometriosis were visible or not. Naturally, I would prefer to avoid a diagnosis of endometriosis, yet acknowledging that there is something atypical within my body could allow me to seek appropriate treatment options. I am curious to know—understanding that this is purely speculative—whether the sonographer's comment regarding the lack of concern typically suggests there were no visible signs of endometriosis, and if it turns out not to be endometriosis, what other explanations might exist for my symptoms? I appreciate any insights you can provide.
Achilles Tendon Rupture - 45mm Gap: Is Surgery Necessary?
Greetings, Medical Professionals! My mother, who is 50 years old, sustained a ruptured Achilles tendon the previous Saturday. It wasn't until Thursday that she was able to undergo an ultrasound. The results revealed a complete rupture with a staggering 45mm gap between the two ends of her tendon. We visited the emergency department, where she was fitted with a plaster splint for her leg, and the recommendation was to return in a fortnight for follow-up. Based on my research through various medical literature, such a significant gap typically suggests that surgical intervention is essential without delay. What options are available to us?
28-Year-Old Female Experiencing Unintentional Weight Loss
Five months prior, my weight was 120 kilograms, but it has since dropped to 98 kilograms. I have noticed a significant decline in my appetite, yet I feel like I might still be consuming a considerable number of calories. This situation began with gastrointestinal issues, including nausea and frequent diarrhea. At that time, I was prescribed several psychiatric medications for bipolar affective disorder (BPAD), specifically clozapine, lithium, and venlafaxine, but had to discontinue them because I couldn't tolerate them anymore. I am currently taking asenapine, which I believe has a more neutral metabolic profile. Upon returning from a trip to Singapore, I suspected that I might have contracted a virus there. I underwent various tests, including blood and stool analyses. My full blood exam and electrolytes returned normal results, as did the C-reactive protein and thyroid-stimulating hormone levels, although I did have a slight iron deficiency. The fecal calprotectin level was marginally elevated, but the fecal PCR and cultures came back normal. Recently, I had the opportunity to trial a continuous glucose monitor (CGM). I experienced several episodes of hypoglycemia, leading me to think that I might be experiencing minor insulin dumping, which could be linked to a gastric sleeve procedure I underwent about five years ago. That surgery initially helped me shed approximately 15 kilograms, but within four years, I regained around 30 kilograms. While my stomach capacity remains reduced, I am able to consume a substantial quantity of food. Approximately three months ago, I underwent both gastroscopy and colonoscopy. These procedures revealed some aphthous ulcers, which are clinically suggestive of mild Crohn’s disease, but not enough inflammation was present for a definitive diagnosis based on histopathology. During my consultation with a gastroenterologist, I had just started Humira for hidradenitis. The doctor mentioned that while Humira would potentially help with Crohn's, my condition was so mild that even without the medication, he would not recommend any specific treatments. He surmised that my diarrhea might be stress-induced, and although I am often under pressure as a junior doctor, I typically gain weight during stressful periods. I've been experiencing early morning awakenings and a degree of heat intolerance. On a positive note, my mental health is currently in a good place. I do not smoke or use recreational drugs. I consume alcohol socially and maintain an active lifestyle, attending the gym three times a week. Existing medical conditions include: - Narcolepsy - Hidradenitis - BPAD Type 1 Current medications are as follows: - Humira - Dexamphetamine (which I've actually reduced after years of use) - Armodafinil - Asenapine I remain pleased with my weight loss, as this feels like the simplest dieting experience I've had. However, I'm uncertain whether this weight reduction signifies any underlying issues. My gastroenterologist plans to reassess me in six months with another calprotectin level check, and he does not appear to be worried at this time. Are there additional blood tests I should be considering?
Chest CT Findings and Concerns
I’m a 48-year-old woman with a history of smoking. Recently, I underwent a chest CT scan prompted by the discovery of a pulmonary nodule in a previous x-ray. I will share my results and additional details shortly. **CT CHEST Summary:** The scan revealed several indeterminate pulmonary nodules that are new developments since July 2023. A CT scan of the abdomen and pelvis is suggested, along with a review of associated systems. A respiratory consultation may also be beneficial. Additionally, there’s a 5mm low attenuating nodule found in the right lobe of my thyroid. An ultrasound is recommended for further evaluation due to the pulmonary findings, recognizing that CT is not the best method for assessing this. The dense breast tissue observed is also challenging to evaluate via CT. It’s advisable to ensure that recent mammograms or ultrasounds are conducted and correlated with any clinical evaluations. **Clinical Context:** The CT scan was performed primarily for the evaluation of the detected pulmonary nodule. **Findings:** The report references a CTPA conducted on July 21, 2023. I have a clear central trachea and tracheobronchial tree, with no noteworthy lymph node enlargement in the hilar or mediastinal regions. Multiple pulmonary nodules were marked as indeterminate in nature on key images, with 86 nodules identified, mostly measuring less than 5mm. There is no evidence of cavitation, and the lung background does not strongly suggest sarcoidosis. While metastasis is a possibility, these nodules are currently regarded as unclear in significance and warrant correlation with previous imaging. There were no signs of pleural or pericardial effusions observed. The low attenuating thyroid nodule appears stable since 2023, though it was less distinctly viewed due to the arterial imaging technique. An ultrasound assessment is recommended for thoroughness, even though its morphology closely resembles earlier scans. The examination of the upper abdominal organs revealed no major issues in the arterial phase. No aggressive bone lesions were found. Earlier this year, in February 2023, an abdominal ultrasound revealed a 9x11mm mobile lesion with calcifications in my gallbladder. Although my GP didn’t express concern, I have a follow-up ultrasound scheduled. An abdominal CT scan conducted in April 2024 indicated bibasal subsegmental atelectasis and small bilateral effusions, with the right side being more pronounced. However, these findings appear to have resolved by the time of the current CT, with no pericardial fluid detected at that time. In addition, blood tests from September and November of 2023 reflected mildly elevated hemoglobin, white cell count, and MCH levels; however, these abnormalities have since normalized along with subsequent tests conducted as recently as a few weeks ago. I manage asthma fairly well and haven’t noticed any significant coughing or concerning symptoms apart from intermittent stomach discomfort over the last couple of years, which I attribute to stress due to personal challenges. I occasionally experience chest wall and back pain, likely exacerbated by poor posture. I do not have a known cancer diagnosis. My primary concern is whether the presence of these nodules could be linked to an infection or inflammation I might have experienced in 2023 that has resolved, or if there’s a greater likelihood that these findings are indicative of cancer, considering the number of nodules. So far, no follow-up scans or appointments have been scheduled, and I am struggling significantly with anxiety regarding this situation.
Cortisone Injection Experience
On Monday, I received a cortisone injection in my right knee. My previous injection occurred in January, but I began to feel the pain return. Is it typical to experience soreness four days afterward? It’s not particularly painful unless I move incorrectly. There’s no swelling or redness present, yet I battle severe health anxiety, which leads me to worry that it might be infected, even though it's likely not. I just can’t quite recall the symptoms I experienced during my last treatment.