OpenHealth Q&A

Get answered by medical professionals

Negative Culture Test Yet Experiencing Bladder Infection Symptoms

8/28/2025, 11:41:29 AMMale25-34

A 26-year-old female resident of Northeast Pennsylvania, weighing 191.2 pounds and standing 5 feet 7 inches tall, reported having quit vaping four weeks ago. She has recently been prescribed Macrobid at an urgent care facility following the onset of troubling urinary symptoms. In the past week, she has experienced frequent and urgent urges to urinate, which is unusual for her as she typically does not encounter such intense sensations. The situation escalated to the point where she had a minor accident at her workplace on Tuesday, leaking a small amount of urine. Along with the strong urge to urinate, she has noticed some numbness—indicative of difficulty sensing her urinary flow—and some involuntary trickles during the day. Additionally, she observed that her urine appeared slightly frothy, and both her lower back and abdomen have felt sore and tender. After visiting urgent care, the initial urine dipstick test returned with negative results. Although the staff sent samples for further culture testing, they still provided her with antibiotics (Macrobid). Today, the culture results also came back negative. She reports that the antibiotics have significantly alleviated most of her symptoms, but the discomfort in her back and abdomen persists. She is concerned whether this could be a peculiar type of bacterial infection that wasn't detected or if the cause of her discomfort might be something entirely different. Additionally, she is uncertain whether she should contact her primary care physician regarding the negative culture results or if it would be best to wait and see for the time being.

LupusCrohn's DiseaseInternal Medicine

Answers (1)

Cony

8/28/2025, 11:41:48 AM

OpenHealth AI

It sounds like you’re dealing with persistent urinary symptoms and some discomfort, and it's understandable to feel concerned, especially after receiving negative culture results. Here's a summary of the key points and some guidance on what to consider next.

Summary

You've experienced urinary symptoms that are improving with antibiotics, but there's still discomfort in your back and abdomen. Your urinary culture tests returned negative, which can sometimes happen in cases where symptoms persist.

Explanation

Negative culture results suggest that a typical bacterial urinary tract infection (UTI) might not be present. However, other conditions can mimic these symptoms, such as interstitial cystitis (a chronic bladder condition), pelvic floor dysfunction, or even referred pain from other areas (like kidneys).

Since you've noted improvement with antibiotics, this indicates that there might have been an underlying infection or inflammation. The fact that symptoms are improving is encouraging, but ongoing discomfort warrants further attention to ensure there's no other underlying issue.

Next Steps

  1. Monitor Symptoms: Keep a close eye on any changes in your symptoms. Note any new symptoms, worsening pain, or changes in urination frequency or urgency. This can provide valuable information if you consult a healthcare provider later.

  2. Hydration: Ensure you are drinking enough fluids, as proper hydration can help flush out potential irritants in the urinary tract.

  3. Self-Care for Discomfort:

    • Consider using a heating pad on your lower back and abdomen to help relieve soreness.
    • Over-the-counter pain relievers, such as ibuprofen or acetaminophen, can also be used for pain relief, as long as you do not have any contraindications to these medications.
  4. Follow-up with Your Provider: Since you have ongoing symptoms (especially the discomfort and back pain), it would be advisable to reach out to your primary care physician. You can discuss your negative culture results and ongoing symptoms, which may lead to further evaluation or alternative diagnoses.

  5. Review Lifestyle Factors: Since you recently quit vaping, any changes in your lifestyle might also influence urinary symptoms or discomfort. Consider discussing this with your healthcare provider for tailored advice.

Taking these steps should help address your symptoms while providing a clearer picture of your condition. If you have any concerns about your symptoms or if they worsen, it's always best to seek medical advice sooner rather than later.

Related Questions

Am I Experiencing Symptoms of Lupus?

Laboratory tests reveal the following results: - Activated Partial Thromboplastin Time (APTT): 41.0 seconds Normal Reference Range: 27-39 seconds - Dilute Russell's Viper Venom Test (dRVVT) / dRVVT Excess Phospholipid: 1.7 Diagnosis of Antiphospholipid Syndrome (APS) necessitates abnormalities to persist for over three months. Normal Result: <=1.3 - C-Reactive Protein Level: 1.8 mg/L A 30-year-old female with a generally healthy background, I have had two pregnancies; the second resulted in an emergency cesarean section. Five months after giving birth, I experienced dissections in both the left internal carotid artery and the right vertebral artery. Shortly after, I suffered a "stroke" that caused weakness and numbness on the right side of my body. Although these symptoms have lessened, they are still present four months later. Only now are the doctors beginning to perform tests to uncover the cause behind these arterial dissections. My next appointment is still a few weeks away, and I am eager to understand what these lab results might indicate. All other test results came back within normal limits.

ArthritisLupusEndocrinology
Male25-34
12 minutes ago

Understanding C5-6 Disc Protrusion

At the age of 37, I've been struggling with various symptoms, including dizziness, persistent headaches, occasional blurry vision, neck discomfort, and inflammation in my trapezius area since the end of May. This ordeal has lasted three months, and I am deeply frustrated. Standing for extended periods often leads to feelings of lightheadedness along with an increased heart rate, though I do feel somewhat relieved with movement. I initially had a cervical spine x-ray, which returned normal results. Despite this, my ongoing visits to both a chiropractor and a massage therapist did not alleviate my symptoms. Recently, I underwent an MRI of my cervical spine, which revealed a left paracentral disc protrusion at the C5-C6 level, accompanied by mild central canal stenosis. According to my physician, these MRI findings correspond with the symptoms I have been experiencing. He referred me to physical therapy, and mentioned that if there is no improvement, we may consider an epidural steroid injection as the next step. I am optimistic that physical therapy will provide some relief, even though I have just begun. However, I can't shake off the frustration stemming from the persistent pain and continuous lightheadedness. Does this symptomatology align with the diagnosis I've received? Moreover, is it common to endure these complications for a duration of three months? Additionally, my doctor has scheduled a brain MRI for me next week as a precautionary measure.

AsthmaCOPDInternal Medicine
Male25-34
32 minutes ago

Lymph Node Biopsy Results - Is It Cancer?

A 23-year-old woman with no smoking history and generally good health discovered a lump in her neck and jaw region, specifically under her ear and behind the jawbone, during 2023. After struggling to get answers regarding the lump, she underwent an ultrasound eight months ago, which revealed a mildly enlarged lymph node. A follow-up appointment that was initially scheduled for six months later ended up being delayed, leading her to have another ultrasound last week. The results showed that the lymph node had grown in size, increasing from approximately 1.8 mm to around 2.1 mm. Just yesterday, she had a biopsy performed, and the results became available today. The findings indicated the presence of "rare small mature lymphocytes" and recommended that a repeat biopsy be conducted. After researching online, she found alarming information linking her symptoms to cancer. With the doctor's office yet to reach out, she is feeling anxious and is trying to understand what this means for her health.

LupusInternal MedicineEndocrinology
Male25-34
32 minutes ago

Concerns About Heart Issues

At 16 years old, I stand about 5'7" (or 171 cm) and weigh around 68 kg. Ever since the pandemic, I’ve experienced some unsettling symptoms. Although my case of COVID-19 wasn't severe, I've noticed that during my short 15-minute walk to my new school, which requires less walking and more use of public transportation, my heart rate accelerates significantly. Whenever I walk, even a distance as short as five minutes, my heart rate can soar past 150 beats per minute, with my record high hitting 192 bpm after about 10 to 15 minutes of walking uphill. The incline isn’t the steepest, yet I feel it takes a toll. It feels particularly worse in the summer, and it seems to have gradually escalated. When I walk for more than a few minutes, I tend to sweat profusely, and I often deal with shortness of breath, along with occasional chest pain. From early 2022 to early 2025, I dislocated both of my knees twice, totaling four dislocations and two surgeries. Since then, I've had prolonged breaks from walking but have engaged in physical therapy, yet my heart rate continues to be a concern regardless of my efforts to walk to school. I find that my symptoms worsen during the warmer months; even a thrilling game can prompt significant sweating. Although I’m eager to improve my fitness, the rapid heart rates leave me feeling exhausted, so I tend to avoid physical activities. My resting heart rate typically falls between 80 and 90 beats per minute, occasionally hitting 100 even when I’m just relaxing. I’ve mentioned my concerns to my mother, but she brushed them off, attributing them to being out of shape, which is frustrating. I have researched conditions like POTS, tachycardia, and anemia, but I haven’t encountered anything that mirrors my experience precisely. I am feeling uncertain about how to proceed, particularly in convincing my mother or scheduling a doctor's appointment to discuss my symptoms further.

Thyroid DisordersCOPDInternal Medicine
Male25-34
41 minutes ago

Unexplained Discomforts

Since March, I've been experiencing intermittent symptoms of acid reflux and heartburn, leading to a diagnosis of gastritis in June following an endoscopy. I underwent four ECGs, blood tests, and a chest X-ray in April, all of which returned normal results. My most recent ECG was conducted in July. Currently, I am on proton pump inhibitors (PPIs) to manage my gastritis and have adopted a bland diet to alleviate discomfort. Despite these measures, I continue to endure chest pain that feels more like muscle strain in the sternum, lower left ribs, under my armpits, and across my chest on both sides. Occasionally, I also experience back pain correlating with the chest discomfort, and recently, I've developed sharp pain on my mid-right side. It seems my gastritis symptoms have lessened, but I am unable to take NSAIDs owing to the condition, so paracetamol is my only option for pain relief when necessary. I've scheduled a heart monitor for two weeks, anticipated for the end of next month, to eliminate the possibility of any heart-related concerns. I have attended numerous medical appointments, and just when I feel I am gaining control over my symptoms, a new one emerges. At 31 years old, I do not smoke or drink, and I regularly exercise, balancing life as a mother of two young children. Notably, when I move my left arm or shoulder, I hear a clicking and grinding sound. I've arranged a physiotherapy session in a few weeks. Could these symptoms be indicative of fibromyalgia, costochondritis, or perhaps my body just reacting to various stresses? I’m feeling quite overwhelmed and am anxious about the possibilities.

ArthritisFibromyalgiaInternal Medicine
Male25-34
49 minutes ago