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Negative Culture Test Yet Experiencing Bladder Infection Symptoms

8/28/2025, 11:41:29 AMMale25-34

A 26-year-old female resident of Northeast Pennsylvania, weighing 191.2 pounds and standing 5 feet 7 inches tall, reported having quit vaping four weeks ago. She has recently been prescribed Macrobid at an urgent care facility following the onset of troubling urinary symptoms. In the past week, she has experienced frequent and urgent urges to urinate, which is unusual for her as she typically does not encounter such intense sensations. The situation escalated to the point where she had a minor accident at her workplace on Tuesday, leaking a small amount of urine. Along with the strong urge to urinate, she has noticed some numbness—indicative of difficulty sensing her urinary flow—and some involuntary trickles during the day. Additionally, she observed that her urine appeared slightly frothy, and both her lower back and abdomen have felt sore and tender. After visiting urgent care, the initial urine dipstick test returned with negative results. Although the staff sent samples for further culture testing, they still provided her with antibiotics (Macrobid). Today, the culture results also came back negative. She reports that the antibiotics have significantly alleviated most of her symptoms, but the discomfort in her back and abdomen persists. She is concerned whether this could be a peculiar type of bacterial infection that wasn't detected or if the cause of her discomfort might be something entirely different. Additionally, she is uncertain whether she should contact her primary care physician regarding the negative culture results or if it would be best to wait and see for the time being.

LupusCrohn's DiseaseInternal Medicine

Answers (1)

Cony

8/28/2025, 11:41:48 AM

OpenHealth AI

It sounds like you’re dealing with persistent urinary symptoms and some discomfort, and it's understandable to feel concerned, especially after receiving negative culture results. Here's a summary of the key points and some guidance on what to consider next.

Summary

You've experienced urinary symptoms that are improving with antibiotics, but there's still discomfort in your back and abdomen. Your urinary culture tests returned negative, which can sometimes happen in cases where symptoms persist.

Explanation

Negative culture results suggest that a typical bacterial urinary tract infection (UTI) might not be present. However, other conditions can mimic these symptoms, such as interstitial cystitis (a chronic bladder condition), pelvic floor dysfunction, or even referred pain from other areas (like kidneys).

Since you've noted improvement with antibiotics, this indicates that there might have been an underlying infection or inflammation. The fact that symptoms are improving is encouraging, but ongoing discomfort warrants further attention to ensure there's no other underlying issue.

Next Steps

  1. Monitor Symptoms: Keep a close eye on any changes in your symptoms. Note any new symptoms, worsening pain, or changes in urination frequency or urgency. This can provide valuable information if you consult a healthcare provider later.

  2. Hydration: Ensure you are drinking enough fluids, as proper hydration can help flush out potential irritants in the urinary tract.

  3. Self-Care for Discomfort:

    • Consider using a heating pad on your lower back and abdomen to help relieve soreness.
    • Over-the-counter pain relievers, such as ibuprofen or acetaminophen, can also be used for pain relief, as long as you do not have any contraindications to these medications.
  4. Follow-up with Your Provider: Since you have ongoing symptoms (especially the discomfort and back pain), it would be advisable to reach out to your primary care physician. You can discuss your negative culture results and ongoing symptoms, which may lead to further evaluation or alternative diagnoses.

  5. Review Lifestyle Factors: Since you recently quit vaping, any changes in your lifestyle might also influence urinary symptoms or discomfort. Consider discussing this with your healthcare provider for tailored advice.

Taking these steps should help address your symptoms while providing a clearer picture of your condition. If you have any concerns about your symptoms or if they worsen, it's always best to seek medical advice sooner rather than later.

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