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Seeking Advice for a Widespread Itchy Rash

8/28/2025, 2:42:32 AMMale25-34

I’m a 21-year-old woman, standing 5'8" tall and weighing 220 pounds. This past Sunday, I discovered a rash forming on my wrist. It consisted of numerous small, raised, reddish bumps that were extremely itchy. By Monday morning, the same type of bumps appeared along the perimeter of my lips. As the day progressed, the rash spread to my inner thighs, legs, and hands. Now, it has even reached my face, the insides of my elbows, behind my knees, and my chest. On Monday, I visited an urgent care facility, where they prescribed me a 5-day regimen of Prednisone. Regrettably, it hasn’t alleviated my symptoms. Since last night, I’ve been experiencing significant brain fog and extreme fatigue. My temperature rose to 99.5°F, but it didn’t exceed that. Additionally, my resting heart rate surged to 120 beats per minute. I’m at a loss regarding what might be causing this. To give some background on my recent health, I began taking Pantoprazole last Friday but discontinued it on Monday, suspecting it might be the culprit. I recently overcame a yeast infection, and just last week, results from a urinalysis indicated the presence of blood and leukocyte esterase. I’m reaching out to see if anyone might have insights into what could be behind this rash and my other symptoms.

LupusCrohn's DiseaseInternal Medicine

Answers (1)

Cony

8/28/2025, 2:42:50 AM

OpenHealth AI

It sounds like you're experiencing a widespread, itchy rash accompanied by fatigue and changes in your vital signs, which is understandably concerning. Initial treatment with Prednisone hasn’t provided relief, and you’re experiencing new symptoms of brain fog and fatigue. Let's break this down to help you identify potential causes and decide on your next steps.

Understanding Your Symptoms: The symptoms you describe could stem from various causes, including:

  • Allergic Reaction: Contact dermatitis or an allergy to medication or another substance may lead to this type of rash.
  • Infection: Sometimes skin rashes can be related to systemic infections or conditions like viral exanthems.
  • Autoimmune Conditions: Although less common, autoimmune issues could manifest similarly.
  • Gastrointestinal Connection: Given your history with Pantoprazole and recent urinary symptoms, there may be a link worth considering.

Next Steps:

  1. Monitor Symptoms: Keep a close eye on your symptoms, especially any worsening of the rash, new areas of involvement, or systemic signs like fever or shortness of breath.

  2. Hydration and Rest: Ensure you're staying hydrated and getting plenty of rest. Fatigue might improve with adequate hydration and sleep.

  3. Topical Care: Consider using over-the-counter hydrocortisone cream on the rash to help reduce itching and inflammation. Additionally, an antihistamine like diphenhydramine (Benadryl) can help relieve itching, but be cautious of the sedative effects it may have.

  4. Record Changes: Document any new symptoms or changes in your rash. Tracking this will help you identify patterns and provide useful information if you need to seek further help.

  5. Consult a Healthcare Professional: Since your symptoms have progressed and the prescribed treatment hasn’t worked, it's essential to follow up with a healthcare provider. They may want to reassess your situation, potentially perform tests to rule out infections or other underlying conditions, and adjust your treatment plan accordingly.

When to Seek Immediate Help: If you experience significant shortness of breath, swelling in the throat or face, or a high fever, please seek immediate medical attention.

I understand how distressing these symptoms can be; please know you're taking a positive step by seeking advice. Let me know if you have any more questions or need further clarification on your situation!

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