OpenHealth Q&A

Get answered by medical professionals

Concerns About Ibuprofen and Flurbiprofen Usage

8/27/2025, 7:12:03 PMMale25-34

Hello everyone, I've been dealing with a sore throat for the past few days, and the discomfort has become quite severe. In an attempt to alleviate the pain, I decided to take two doses of Ibuprofen 400, along with several sprays of Flurbiprofen, roughly 6 to 8 applications, which equate to about 17.5 - 20 mg of Flurbiprofen. Additionally, I consumed 1 or 2 lozenges, each containing 8.75 mg of Flurbiprofen. However, I recently discovered that mixing these medications might not be advisable. Should I have any concerns regarding this combination? For context, I am 27 years old, weigh 75 kg, am generally in good health, and I have no known medical issues. I've also had a normal diet today. Thank you!

Pain ManagementAbdominal PainChronic Pain

Answers (1)

Cony

8/27/2025, 7:12:21 PM

OpenHealth AI

It's understandable to feel concerned about the medications you've taken for your sore throat, especially after realizing there might be issues with combining them. Let’s break down your situation.

Main Points:

  1. Ibuprofen and Flurbiprofen Combination: Generally, it’s important to avoid excessive doses of similar classes of medications.
  2. Current Dosage Safety: Your combined intake of Flurbiprofen exceeds typical recommendations, which could be a concern.
  3. Next Steps: Monitor for any side effects, and consider alternative pain relief strategies.

Explanation:

Ibuprofen and Flurbiprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs) that work to reduce pain and inflammation. Using both can lead to an increased risk of side effects such as stomach irritation, ulcers, and even kidney problems, especially if taken in high doses or over extended periods.

From your description:

  • You took 400 mg of Ibuprofen.
  • You applied 17.5 - 20 mg of Flurbiprofen through sprays and consumed additional 17.5 mg via lozenges.

While your total intake of Flurbiprofen from all sources may not seem excessive, combining NSAIDs can complicate how they affect your stomach and kidneys.

Next Steps:

  1. Monitor for Symptoms: Pay attention to any signs of stomach pain, nausea, dizziness, or unusual fatigue. If you experience these, it could indicate a reaction to the medications.
  2. Limit Additional NSAIDs: For at least the next 24-48 hours, avoid further doses of both Ibuprofen and Flurbiprofen. Consider using acetaminophen (Tylenol) instead for pain relief if needed, following the recommended dosage.
  3. Stay Hydrated: Drink plenty of fluids, which can help soothe your throat and reduce discomfort.
  4. Rest: Prioritize rest to help your body recover from the sickness causing the sore throat.
  5. Alternative Relief for Sore Throat: Consider warm saltwater gargles or honey in tea, which can help soothe throat pain without the risk associated with medications.

If your symptoms worsen or do not improve in a few days, consider consulting a healthcare professional for further advice. It’s always better to be cautious, especially with medication combinations. Take care!

Related Questions

Navigating Motion Sickness and Cybersickness

Hello everyone! I'm a 16-year-old female, with a height of 162 cm, and I’ve dealt with motion sickness for most of my life. Recently, however, it has worsened significantly, extending to cybersickness as well. Spending more than 25 minutes in front of a screen leads to severe discomfort—something that is particularly challenging since I need to use screens for my schoolwork and beyond. After these episodes, I often find myself unable to do anything but lie in bed for the remainder of the day, wrestling with nausea or even vomiting. This issue doesn’t just arise from screen time; I also experience stomach upset during walks or jogs, which leaves me puzzled about how to alleviate this condition. I frequently rely on over-the-counter travel sickness medication, specifically Avomine, and while it does offer some relief, the effect is minimal. I’m seeking advice or suggestions that might help me regain a sense of normalcy in my daily life. For your reference, I don't smoke and only consume alcohol on very rare occasions. I’m located in the UK! Any tips would be greatly appreciated!

NeurologyHeadacheAbdominal Pain
Male25-34
34 minutes ago

Persistent Pain in the Right Flank: Seeking Insights

Greetings, medical professionals. I'm a 38-year-old woman, having recently celebrated my birthday. My daily regimen includes multivitamins with iron, and I occasionally take Valtrex, though it hasn't been necessary for some time. Standing at 5 feet 3 inches and weighing 140 pounds, I have endured this discomfort for the last three to four months, although I've suffered intermittently for approximately five years, with no definitive diagnosis from various doctors. The pain manifests as a sharp sensation near my belly button, resembling a knife stabbing me. In addition, I experience a general ache in the right flank and my lower back. This discomfort ranges from my ribs on the right side right down to my hips and pelvis, affecting areas near my ovaries and the region close to my belly button. I’ve noticed that certain stretches can intensify the pain along the backside of my ribs during movement. I've undergone an abdominal CT scan and a thorough medical examination, revealing no kidney issues, gallstones, appendicitis, or ovarian cysts, and my blood work appears normal. A HIDA scan indicated that my gallbladder operates at merely 23%, but I have not experienced any gallbladder attacks. An endoscopy indicated mild gastritis, but otherwise, the results were acceptable. Does this situation resonate with anyone? I'm puzzled about what could be present near my navel if appendicitis is ruled out. My doctor suggested a connection to my IBS-C, but my bowel movements have been regular, occurring once daily with normal consistency. During my examination, my abdomen was pressed, and she noted tenderness near my belly button, attributing this to local inflammation, as there are no significant organs in that area aside from the small intestine. Any advice or insights would be appreciated, as this has been an ongoing issue since 2020.

Joint PainAbdominal PainMuscle Pain
Male25-34
54 minutes ago

Severe Pain in Lower Right Abdomen for Two Weeks

Hello everyone, I am an 18-year-old assigned female at birth, weighing 65 kilograms and standing at 5 feet 3 inches tall. I have been experiencing intense discomfort in my lower right abdomen since January 28th. On that evening, I sought medical attention and was given codeine for the pain before being sent home. However, due to the persistent agony, I returned to the hospital on January 31st, where I was admitted for the night. There, I underwent numerous tests, including blood tests, a CT scan, and two ultrasounds, yet all results appeared normal. Tests confirmed that my kidneys, intestines, ovaries, uterus, and, critically, my appendix were all unaffected. After a night in the hospital, I was discharged once more with codeine to help manage the pain. As of February 7th, the discomfort remains excruciating—so much so that even minor movements are painful without the assistance of codeine. My bowel and urinary habits remain consistent with my normal routine. Yet, I find myself feeling frightened. The level of discomfort I’m experiencing is unlike anything I've endured before, and there's been no improvement. I’m apprehensive about relying on opioid medication due to fears of developing an addiction, but the reality is that I can't manage the pain effectively without them. The symptoms I’m experiencing closely mimic those of appendicitis, except there's no accompanying fever, vomiting, or any indicators of appendicitis from my tests. The pain amplifies with movement and contact, and oddly, when my lower left abdomen is touched, it triggers pain in the lower right. I’m at a loss about what to do next. The possibility of pregnancy and a urinary tract infection have already been ruled out. Should I consult my general practitioner? I hesitate to do so, as I worry about overburdening healthcare resources, but I’m genuinely struggling to live in this state. The side effects from codeine, including severe memory loss and disrupted sleep patterns, only add to my distress—yet it’s the only solution I have that alleviates the pain. What steps should I take next? What might this condition be?

Joint PainAbdominal PainMuscle Pain
Male25-34
1 hour ago

Navigating Iron Levels: A Personal Journey

At 36, I find myself grappling with iron deficiency issues ever since I had a copper IUD placed. Though I had it removed three years ago, my ferritin levels still remain troublingly low; I've seen some progress—up from a previous 5—yet it’s still far from satisfactory. Currently, I take heme optifer iron three times a week to try to boost my levels. During my initial blood test, I was fasting and had halted my iron supplements for a full day prior. The results were perplexing, leading me to pause my iron intake for another two weeks before submitting blood work again. The recent results showed: - Iron: 32.7 umol/L - Transferrin: 1.74 g/L - Transferrin Saturation: 0.74 - TIBC: 44 umol/L - Ferritin: 29 I’m struggling to understand these findings. Is it typical to have such high transferrin saturation whilst my ferritin remains low? More importantly, what strategies can I use to elevate my ferritin levels to the desired range of 50 to 60 given these blood test results?

Pain ManagementAbdominal PainMuscle Pain
Male25-34
2 hours ago

Swelling and Discoloration at the Tip of My Big Toe

I am a 34-year-old assigned female at birth, standing 6'1" and weighing 225 pounds. I do not smoke and my current medications include Lexapro, Metformin, and Tirzepatide. Recently, I accidentally trimmed my toenail a bit too short, though there was still visible nail left. Initially, I experienced some discomfort accompanied by redness, tightness, and swelling around the toe, but I decided to manage it without seeking immediate attention. However, a few days ago, I began to notice the emergence of purple dots and streaks, which have progressively worsened. Furthermore, I have also detected a painful purple area at the edge of my second toenail, which is surprising as I haven’t trimmed them in several weeks. I would appreciate any insights on this issue, as I’d like to avoid unnecessary expenses for a medical consultation that may lead to a dismissive response like “just let it grow out.”

Pain ManagementJoint PainAbdominal Pain
Male25-34
2 hours ago