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Concerns About Ibuprofen and Flurbiprofen Usage

8/27/2025, 7:12:03 PMMale25-34

Hello everyone, I've been dealing with a sore throat for the past few days, and the discomfort has become quite severe. In an attempt to alleviate the pain, I decided to take two doses of Ibuprofen 400, along with several sprays of Flurbiprofen, roughly 6 to 8 applications, which equate to about 17.5 - 20 mg of Flurbiprofen. Additionally, I consumed 1 or 2 lozenges, each containing 8.75 mg of Flurbiprofen. However, I recently discovered that mixing these medications might not be advisable. Should I have any concerns regarding this combination? For context, I am 27 years old, weigh 75 kg, am generally in good health, and I have no known medical issues. I've also had a normal diet today. Thank you!

Pain ManagementAbdominal PainChronic Pain

Answers (1)

Cony

8/27/2025, 7:12:21 PM

OpenHealth AI

It's understandable to feel concerned about the medications you've taken for your sore throat, especially after realizing there might be issues with combining them. Let’s break down your situation.

Main Points:

  1. Ibuprofen and Flurbiprofen Combination: Generally, it’s important to avoid excessive doses of similar classes of medications.
  2. Current Dosage Safety: Your combined intake of Flurbiprofen exceeds typical recommendations, which could be a concern.
  3. Next Steps: Monitor for any side effects, and consider alternative pain relief strategies.

Explanation:

Ibuprofen and Flurbiprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs) that work to reduce pain and inflammation. Using both can lead to an increased risk of side effects such as stomach irritation, ulcers, and even kidney problems, especially if taken in high doses or over extended periods.

From your description:

  • You took 400 mg of Ibuprofen.
  • You applied 17.5 - 20 mg of Flurbiprofen through sprays and consumed additional 17.5 mg via lozenges.

While your total intake of Flurbiprofen from all sources may not seem excessive, combining NSAIDs can complicate how they affect your stomach and kidneys.

Next Steps:

  1. Monitor for Symptoms: Pay attention to any signs of stomach pain, nausea, dizziness, or unusual fatigue. If you experience these, it could indicate a reaction to the medications.
  2. Limit Additional NSAIDs: For at least the next 24-48 hours, avoid further doses of both Ibuprofen and Flurbiprofen. Consider using acetaminophen (Tylenol) instead for pain relief if needed, following the recommended dosage.
  3. Stay Hydrated: Drink plenty of fluids, which can help soothe your throat and reduce discomfort.
  4. Rest: Prioritize rest to help your body recover from the sickness causing the sore throat.
  5. Alternative Relief for Sore Throat: Consider warm saltwater gargles or honey in tea, which can help soothe throat pain without the risk associated with medications.

If your symptoms worsen or do not improve in a few days, consider consulting a healthcare professional for further advice. It’s always better to be cautious, especially with medication combinations. Take care!

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