Unexplained Discomfort in the Upper Right Abdomen
I'm a 32-year-old male, standing 5'9" and weighing 150 pounds, and I've been experiencing sporadic pain in my upper right abdomen for approximately two and a half years. These episodes typically last about a week and can disappear for several months before reappearing. Despite undergoing numerous blood tests and imaging studies, including MRIs, CT scans, ultrasounds, and X-rays, all results have shown no abnormalities, leaving me without a solid diagnosis for this discomfort. Over the last two to three weeks, the pain has intensified more than ever. Although it continues to fluctuate, there are days when the pain only occurs once and lasts for about 15 to 20 minutes. On other occasions, it can persist throughout the day, with episodes ranging from 5 to 30 minutes each. I don’t take any regular medications, but I do use Albuterol roughly twice a year. Additionally, during the winter, I supplement with 300 mg of magnesium, 125 mcg of vitamin D3, and 100 mcg of vitamin K2. I maintain a relatively healthy lifestyle; I don’t smoke and enjoy a few beers, typically Coors Light, socially about once or twice a week. In terms of my medical history, I have previously dealt with GERD, chronic inactive gastritis, and an H. pylori infection which has been cleared for about four years. My GERD and acid reflux symptoms have also become infrequent, occurring only every few months. Despite my attempts to identify potential triggers for this abdominal pain, I’ve been unsuccessful as the occurrences seem entirely unpredictable, and changes to my routine do not alleviate the discomfort. This is my first time sharing this issue, so if there’s anything I’ve overlooked, feel free to ask me in the comments or suggest additional information that I could include. Thank you for any insights you might provide!
Answers (1)

8/25/2025, 12:21:19 AM
OpenHealth AI
It sounds like you’ve been through a lot regarding your upper right abdominal discomfort. Since you’ve experienced this for over two years, and especially since the pain has intensified recently, it’s understandable to feel frustrated and concerned. Let's break down your situation and options clearly.
Main Points
- Your abdominal discomfort has persisted for a long time, with periods of worsening pain.
- Extensive medical evaluations have not identified a specific cause.
- You have a history of GERD and gastritis, which could be related to these symptoms.
Explanation
The upper right abdomen can house various organs, including the liver, gallbladder, and parts of the intestines, but your previous tests showing no abnormalities are reassuring. The sporadic nature of your pain, combined with your medical history, suggests a few possible considerations:
- Musculoskeletal Pain: Sometimes, pain in the abdomen can originate from muscles or the ribs, which might not show up on imaging.
- Functional Dyspepsia: This can occur even if you don't have active GERD and can cause discomfort without clear abnormalities on tests.
- Gallbladder Issues: Even if initial tests were normal, gallbladder dysfunction (like biliary dyskinesia) can cause intermittent pain.
- Nerve-related Pain: Nerve irritation in the abdominal region can cause sporadic episodes of pain.
Next Steps
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Track Your Pain: Keep a detailed diary of your pain episodes, including time of day, intensity, duration, and any food or activities associated with the pain. This could help identify potential patterns or triggers.
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Consider Dietary Adjustments: Even minor changes might help reduce discomfort. Try a food elimination diet, eliminating one potential trigger (like fatty or spicy foods) at a time, for two weeks to see if symptoms improve.
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Maintain Hydration: Ensure you’re drinking enough water throughout the day, as dehydration can sometimes exacerbate discomfort.
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Explore Stress Management: Stress and anxiety can lead to abdominal discomfort. Practices like mindfulness, yoga, or gentle exercise could help manage any stress-related symptoms.
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Follow-Up with a Specialist: Since your pain has intensified, consider returning to your healthcare provider for a follow-up. You might discuss further evaluations (like a referral to a gastroenterologist or a pain specialist) and explore alternative diagnostics for conditions like functional disorders or musculoskeletal issues.
Continued Support
It's important to continue seeking answers and not to feel discouraged. Pain can often be complex and multifactorial. Let me know if you need more specific strategies or information about any of the steps!
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