Determining Between Cold Sores and Angular Cheilitis
(39F) In the past, I've experienced cold sores, but this time felt a familiar sensation on Thursday evening. By Friday evening, I had a prescription for cold sore treatment. Today, however, I find a painful spot in my nose accompanied by dry, flaky skin around my lips and nostrils, in addition to the existing sores. Did the medication have an effect last night after my first dose, or is a longer period required for it to take effect? Could this be an indication of something different, or perhaps a severe reaction stemming from my recent use of the CPAP machine, which I am still struggling to acclimate to? I currently utilize a Resmed F20 full face mask.
Answers (1)

8/23/2025, 7:50:55 PM
OpenHealth AI
It sounds like you're experiencing some significant discomfort with potential cold sores and new symptoms around your nose and lips. Let's break this down:
Main Points
- You may be dealing with cold sores, but the additional symptoms of dry, flaky skin and pain suggest that you could also have angular cheilitis or irritation from your CPAP mask.
- Immediate actions include maintaining moisture around your lips, ensuring proper hygiene, and observing the healing process of your cold sores.
Explanation
Cold sores are typically caused by the herpes simplex virus and can manifest as blisters or sores on or around the lips. Treatment usually begins to work within a day or two, but if you're seeing new symptoms like flaky skin or pain in the nostrils, it may indicate another issue, such as angular cheilitis. This condition can result from dryness, irritation, or fungal infection, often exacerbated by factors like a CPAP mask if not fitted properly or if it causes moisture accumulation.
Next Steps
- Moisturize: Apply a gentle lip balm or emollient on your lips and the skin around your nose to keep it hydrated.
- Analyze CPAP Use: Check your CPAP mask fit to ensure it’s not too tight, which can cause skin irritation. Make sure to clean it regularly to prevent potential infections.
- Monitor Symptoms: Keep an eye on the new symptoms. If the painful spot or dryness persists or worsens, consider adjustments to your skincare or a change in how you use your CPAP.
- Follow Treatment: Continue taking your cold sore medication as prescribed, and give it some time to work. Monitor for any change in your cold sore symptoms.
- Avoid Irritants: Stay away from harsh soaps or skin products around the affected areas to reduce irritation.
If symptoms do not improve in the next few days or if they worsen, consider re-evaluating your treatment plan for your cold sores or the irritation you’re experiencing. Take note of how you feel and seek support if needed. Remember, it’s important to take care of both your physical and emotional well-being as you navigate these symptoms.
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