Concerns About Cortical Atrophy at 27
Hello, everyone. I am a 27-year-old diagnosed with multiple sclerosis. Recently, following a flare-up, I underwent an MRI. The report included a statement indicating "cortical atrophy with bifrontal predominance." Is this something that can be considered typical for someone in their late twenties? As a psychologist, I'm acutely aware of my significant cognitive challenges that interfere with daily activities, and this new finding has left me feeling quite anxious.
Answers (1)

8/22/2025, 7:51:42 PM
OpenHealth AI
It's understandable to feel anxious about the MRI findings of cortical atrophy, especially given your diagnosis of multiple sclerosis (MS). Cortical atrophy refers to a decrease in the size of the cortex (the outer layer) of the brain and can be associated with various neurological conditions, including MS. While some degree of atrophy can occur in people with MS due to the disease's effects, it is less common for individuals in their late twenties.
Explanation:
In MS, changes in the brain can happen over time, and some individuals may experience cognitive challenges as a result. Cortical atrophy can contribute to these cognitive difficulties, and the fact that you’re noticing significant challenges in daily activities is important to address. It’s great that you’re aware of this; being proactive about your mental health and cognitive function is key.
Next Steps:
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Monitor Cognitive Changes: Keep a record of your cognitive challenges, including memory issues, attention problems, or anything else that feels significant. This record will be useful for tracking changes over time.
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Engage in Cognitive Activities: Consider incorporating cognitive exercises or activities into your daily routine. Games, puzzles, or memory tasks can help keep your brain engaged.
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Healthy Lifestyle Choices: Focus on balanced nutrition, regular physical activity, and good sleep hygiene. These factors can support both brain health and general well-being.
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Stress Management Techniques: Implement stress-relief practices such as mindfulness, meditation, or deep-breathing exercises. Reducing stress can have a positive impact on cognitive function.
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Connect with Support: Consider joining a support group for individuals with MS or cognitive challenges. Sharing experiences and strategies can be comforting and helpful.
If your cognitive symptoms worsen or you find them increasingly difficult to manage, it may be beneficial to discuss these concerns with your healthcare team to explore potential interventions tailored to your needs. Remember, you’re not alone in this, and there are pathways to help you manage both your physical and cognitive health.
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