Ongoing Concerns with Elevated Immature Granulocytes
Age: 60 years, Height: 5'10", Weight: 169 lbs, Ethnicity: Caucasian. Issue: For several years, my Complete Blood Count (CBC) has consistently shown elevated Immature Granulocytes. I am a professor of physics at a prominent university in the United States. My medical history includes Type 2 Diabetes (which is well-managed), high cholesterol levels (hypercholesterolemia), panic disorder, seborrheic dermatitis, and mild cognitive impairment. Current Medications: Metformin, Rosuvastatin, Klonopin, Vascepa, Vitamin D3, Nizoral shampoo. Over the past three years, I have been experiencing significant fatigue and breathing difficulties. These symptoms tend to fluctuate, with days of severity followed by some relief. Writing this message is a challenge for me at the moment. Classes are about to resume, and I am uncertain if I will be able to keep up this time. I visited the emergency room on August 16, 2025, and was diagnosed with Diverticulitis, for which I am currently taking Augmentin for ten days. Upon reviewing my bloodwork history, the persistent presence of elevated Immature Granulocytes is a concerning factor. Whenever I discuss this with my primary care physician, she seems dismissive. I often feel that my physical symptoms are misattributed to psychological issues. The latest data point from my IG% levels was recorded during my recent ER visit on August 16, 2025.
Answers (1)
8/18/2025, 6:12:47 PM
OpenHealth AI
I understand that you're dealing with persistent fatigue, difficulty breathing, and elevated immature granulocytes, which can be frustrating and concerning, especially with your upcoming classes. Here’s a clear breakdown of your situation and what you can do next.
Key Points:
- Elevated Immature Granulocytes (IGs): These can indicate ongoing inflammation or a reaction to infection. Elevated IGs may point to a number of conditions, but they are often not a standalone diagnosis.
- Fatigue and Breathing Difficulties: These symptoms can result from various factors, including your underlying conditions, medications, or infections.
- Recent Diverticulitis: Your recent diagnosis and treatment may also be influencing your bloodwork and overall health.
Explanation:
Immature granulocytes can be a response to infection, inflammation, or other stressors on the body. While they aren't specifically a disease marker, their persistent elevation alongside fatigue and breathing issues warrants careful attention. Your diverticulitis and existing health conditions, particularly diabetes and high cholesterol, can also play a role in your overall well-being.
Next Steps:
-
Track Symptoms: Keep a daily journal noting when your fatigue and breathing difficulties occur, their severity, and any other symptoms. This can provide valuable information for your healthcare provider.
-
Follow-Up with Your Doctor: If you feel your concerns are not being addressed adequately, consider requesting a referral to a specialist (like a hematologist or an infectious disease expert) to explore the significance of your elevated immature granulocytes further.
-
Monitor and Manage Chronic Conditions: Ensure your diabetes remains well-managed and stay on top of cholesterol levels with your medications. Good management can help reduce fatigue and associated symptoms.
-
Consider a Comprehensive Evaluation: Ask about a complete workup, including tests for infection, inflammation markers, or other potential causes of your fatigue and breathing difficulties.
-
Connect with Support: If you feel dismissed, it may be helpful to have a family member or trusted friend accompany you to appointments. They can help communicate your concerns more effectively.
-
Self-Care Practices: Maintain a balanced diet, stay hydrated, and incorporate light exercise as tolerated, which can support energy levels. Address any panic disorder symptoms through relaxation techniques or therapy, if not already in place.
-
Consider Psychological Health Support: Given your feelings of being misunderstood, talking with a mental health professional may provide additional coping strategies for dealing with stress and fatigue.
It’s important to advocate for yourself in your healthcare journey, and I encourage you to persist in seeking answers regarding your health concerns. Ensuring your voice is heard can lead to more effective management of your symptoms. Please let me know if you need any more specific information about any of these steps!
Related Questions
Experiencing Uncertainty: Possible Ischemic Attack?
Greetings, everyone, including healthcare professionals. For the past year, I've been managing high blood pressure, and I'm currently prescribed a regimen that includes Amlodipine at 10 mg and Bisoprolol at 5 mg. At 44 years old, I’m a woman who is classified as overweight and also deals with hypothyroidism, low ferritin levels, liver issues, and slightly elevated cholesterol levels. Typically, my medications maintain my blood pressure within a range of 110/70 to 140/80. However, two days ago, I experienced a stressful episode, causing my systolic pressure to spike to 155/95. Upon standing, I sensed weakness in my left arm, which felt as if it were slightly twisting. A wave of panic hit me, and I feared I might be incapacitated or having a stroke. Despite my anxiety, I was still able to grasp a glass and tightly close my fist. Briefly, my right arm felt a mild sensation that lasted only a second. This peculiar feeling persisted for roughly a minute. I then consumed some mint tincture mixed with alcohol and engaged in deep breathing exercises, which remarkably alleviated my symptoms and brought my blood pressure back to a stable level. I contacted my physician, who inquired about my symptoms and their duration. Aside from the discomfort in my arm, I wasn't experiencing any additional issues. A second doctor relieved me of any immediate concerns regarding the necessity for an MRI, and since I underwent one a month prior that showed no abnormalities in my cranial blood vessels, I felt some reassurance. Now, back home and with lingering fears of having experienced an ischemic attack, I wonder if an ultrasound of the neck arteries is warranted. Do my symptoms indicate a potential attack? What steps should I take next? Has anyone faced a similar situation? Thank you all for your insights.
Concerns About Potential Misdiagnosis
Hello everyone, I recently stumbled upon this subreddit and felt it would be the ideal platform to share my experience. I initially posted something similar under r/Asthma but soon realized that this community might be more appropriate for my concerns. To provide some context, I’m a 25-year-old woman with no personal history of smoking, although I have been heavily exposed to secondhand smoke throughout my life. There is a family history of asthma and COPD on my side. I was diagnosed with asthma during childhood but seemed to outgrow it as I got older. Throughout my younger years, I frequently battled respiratory and sinus infections, and in my teenage years, I suffered a severe case of walking pneumonia. Following that episode, my breathing worsened significantly, prompting my doctor to reinstate the asthma diagnosis and prescribe albuterol inhalers without performing any additional tests except for an X-ray to confirm the pneumonia had resolved. Over the years, I’ve noticed a gradual worsening of my symptoms. Each primary care physician I've consulted has prescribed various inhalers and medications, but the relief they provide has been minimal. For years, I have dealt with a persistent dry cough described as that of a seasoned smoker, yet my doctors continuously assured me it was merely asthma, claiming that my inhalers would alleviate it. When a coughing fit does occur, it can be so intense that I end up gagging, losing control of my bladder, and feeling dizzy. Fast forward to two weeks ago: my cough intensifies with physical activity, and I have a physically demanding job. Typically, my inhaler assists me with breathing, but in this instance, it was ineffective, and emergency services were called to administer oxygen. My oxygen saturation dropped to 93% until the oxygen and my rescue inhaler were applied. I declined hospitalization after feeling better with the oxygen. I took a day off work to recuperate. I managed to see my primary care doctor afterward. Having been on Advair and albuterol for years, I was also prescribed Singulair last year due to flare-ups. In my recent visit, my doctor substituted my Ventolin (albuterol) with Airsupra and introduced Spiriva, along with short courses of Mucinex and Prednisone. At the appointment, my lungs sounded clear, and my oxygen levels were between 99-100%. There was no wheezing, just persistent coughing. Returning to work the following Thursday proved challenging; within three hours, I experienced another severe coughing episode that felt as if my throat might rupture. I was gagging, tearing up, and struggling to remain upright, feeling dizzy and breathless. Several doses of my rescue inhaler provided little relief, and emergency services were contacted again; I was subsequently transported to the emergency room. My oxygen saturation was stable at 97-100%, yet I continued to feel breathless and my painful coughing persisted. Respiratory treatments seemed to exacerbate the coughing, and magnesium failed to provide relief. Both the paramedics and ER staff expressed concern when I mentioned my chronic cough that had persisted for years without improvement. Initially, emergency responders detected only a faint wheeze and diminished lung sounds on one side, although they later reported normal findings. No fluid or wheezing was noted, just continued coughing. CT scans and X-rays of my throat and chest returned normal results. After three days in the hospital, my lactic acid and CO2 levels returned to normal. Despite being treated with steroids and cough suppressants, I found no alleviation of my symptoms. I have now received urgent referrals to a pulmonologist, an ENT specialist, and an allergist, and I recently followed up with my primary care physician. Her only recommendation was cough drops and to wait for my upcoming Pulmonary Function Test (PFT). Additionally, the hospital prescribed Pantoprazole for potential GERD, which hasn't significantly helped. My follow-up blood tests revealed that while my CO2 levels improved, they still remain low, and there are no current indications of an autoimmune disorder, though I am awaiting several results. After undergoing the Pulmonary Function Test, the findings were unusual. Though I await an appointment with the pulmonologist, I reviewed the notes from my test. They indicated, "Spirometry is normal. Lung volumes demonstrate hyperinflation and air trapping. Diffusing capacity is normal. No substantial bronchodilator response observed." When I inquired with the technician who administered the test, she mentioned two possibilities: either my lungs weren't inflamed enough to demonstrate a response, which seemed unlikely considering my extensive coughing fits, or the underlying issue might be irreparable with medications. This situation has left me anxious that I may be dealing with more than just severe asthma. For years, I communicated to my doctors that my condition seems to deteriorate, and that none of the prescribed medications eased my cough, yet they continuously reassured me that it was manageable. Now, after being hospitalized, I recognize the critical need to take this seriously. I rarely experience wheezing or fluid but instead contend with a persistent cough similar to that of a long-term smoker. My cough worsens with movement, eating, drinking, taking deep breaths, lying down, waking up, laughing, excessive talking, exposure to extreme temperatures, dry or humid air, stress, and irritants such as dust, smoke, and potent odors. It feels like merely existing prompts my coughing. Although I always have a cough, the triggers mentioned intensify it. I frequently feel congestion in my throat and chest, accompanied by a tight and painful sensation. I have the incessant urge to clear out whatever feels obstructive, but nothing ever emerges. My coughing often leads to dizziness and incontinence. If I'm not actively coughing, I seem to be clearing my throat repeatedly to manage the mucus. During any illness, my cough tends to worsen, resulting in the need for prednisone. Antihistamines provide partial relief solely for nasal symptoms, without helping my throat and chest. When my rescue inhaler does work, its effectiveness lasts only for a short time before I revert to my previous condition. My lungs may feel momentarily unobstructed thanks to the albuterol, but the coughing inevitably returns until my chest aches again. An ER doctor suggested possible diagnoses of Chronic Rhinosinusitis, Post-Nasal Drip, or GERD; however, medications for allergies and acid reflux have not meaningfully addressed my coughing or breathlessness. It does not seem connected to my sinuses but rather feels like my airways are obstructed, hindering deep breaths. Until I meet with the pulmonologist, my best hypothesis has been Cough-Variant Asthma, but given the lack of response to bronchodilators in my PFT, my confidence in that is wavering. In reviewing my results, I cannot help but consider the early stages of COPD or emphysema, especially since my breathing seems to worsen over time, although my age typically mitigates those concerns given my extensive exposure. I've ordered a test for Alpha-1 antitrypsin deficiency from AlphaID to discuss with my pulmonologist just in case. I am certain I have asthma, but I’m beginning to suspect that there may be additional complications involved. For years, my primary care provider dismissed my concerns, despite my insistence that something felt off. It wasn’t until I required EMS intervention that she finally began the referral process to specialists. I find myself in a state of confusion and unease. Has anyone here experienced anything resembling my situation? I'm looking forward to consulting with the pulmonologist about my test results in the coming week or two, but I’m apprehensive that they will simply dismiss my concerns like previous practitioners have done.
Seeking Guidance on Ice Treatment Post-Surgery
I’m a 34-year-old male, weighing 158 pounds and standing 5 feet 6 inches tall. I lead a non-smoking lifestyle, consume three alcoholic drinks weekly, and do not have any known allergies. I'm currently recovering from right hand and wrist surgery, which took place five weeks ago. I need some advice regarding the use of ice for my treatment, as my wrist remains quite swollen. While I understand the advantages of icing, I find the experience quite intolerable. I attempt to immerse my hand and wrist in ice water completely, but the pain is so intense that I can barely last more than 15 seconds. Is this a challenge of mental resilience where I need to push through the discomfort for the sake of a proper 10-minute soak? In the past, I worked with racehorses, and we would apply ice to their legs for 30-minute sessions, significantly accelerating their recovery. I recognize the effectiveness of this method, yet the pain from the cold is unbearable. Should I endure this discomfort for longer periods?
Rash on My Arm: Should I Be Concerned?
Hi there! I’m a 65-year-old female, and for the past four days, I’ve been dealing with a strange rash on my arm. Unfortunately, I can’t visit a healthcare professional until Monday, so I’m hoping to get some clarity in the meantime. I’ll share some images. If they don’t upload here, I’ll post them in the comments instead. The first image, taken last night, is a bit out of focus, but this morning, the rash has appeared even redder. Although it doesn’t itch now, I did experience some itching during the initial two days. As for my health history, I generally don’t have major health concerns apart from elevated cholesterol levels and a recent A1C reading of 5.9, but I do not have diabetes. I keep fairly active for my age group. During the first couple of days, there was some pus, and I managed to clean it with an alcohol wipe, which helped remove it. Could this be related to a spider bite? I noticed some small spiders (specifically daddy long legs) in my bedroom, especially near the balcony door, and I eliminated a few of them today, so that could be a possibility. Should I be wary of any serious complications from this rash? Any advice would be immensely appreciated! My ER co-payment is quite steep, and there’s no urgent care facility nearby. My only option is to request an appointment with my primary care physician next week, but I’m uncertain if it’s something that warrants immediate attention.
Navigating Recurrent Prostate Cancer: A Patient's Journey
As a 60-year-old man living in New York, I faced a challenging battle with prostate cancer approximately 4.5 years ago. My initial biopsy results indicated a Gleason score of 6. However, in September 2025, my PSA levels alarmingly soared to 27.7. To investigate the possibility of an infection, my doctor prescribed a month-long course of antibiotics. Afterward, my PSA levels showed a slight reduction, dropping to 25.5. Following another biopsy procedure, the Gleason score unexpectedly escalated to 10. This prompted serious discussions with my healthcare provider. He explained that, given the radiation treatment I had previously undergone, the surgical removal of my prostate would be quite complex, with very few surgeons willing to perform such a procedure. Consequently, I sought a second opinion from a specialist in urological cancer. The specialist echoed similar concerns, indicating that the potential complications could severely affect the urethra and rectal lining. Instead of surgery, he proposed cryoablation as a viable alternative. Simultaneously, I commenced treatment with testosterone hormone blockers. To say that this experience has been frustrating is an understatement. Most importantly, I also struggle with urination issues that complicate my daily life. I am reaching out for any insights or advice that might assist me in navigating this difficult situation.