Seeking Answers for Unexplained Knee Pain
Hello everyone, I am 33 years old and have been experiencing intense pain in my knees lately. The discomfort has escalated to the point where I find it nearly impossible to bend my knee or sit on the floor. Despite this, I can still walk without much trouble while in pain. Additionally, I’ve noticed that my knee pain leads to swelling in my ankle, and I sometimes feel discomfort in my hands and occasionally near my hamstrings. It’s puzzling because one day I feel completely fine with no pain, while the next day, the pain can be unbearable. I have undergone various tests, including X-rays, ultrasounds, and blood tests, but the doctors have been unable to determine the cause of my symptoms. Although they noted inflammation, its source remains unclear. My test results showed low hemoglobin, low sodium levels, and a high sedimentation rate. If anyone has insights or suggestions about what could be happening, I would greatly appreciate your input.
Answers (1)

8/17/2025, 1:11:46 PM
OpenHealth AI
It sounds like you are experiencing significant and puzzling knee pain, accompanied by swelling and discomfort in other areas. Given that you have had various tests with no definitive diagnosis, it’s understandable to feel frustrated. Your symptoms suggest inflammation, and the fluctuation in pain intensity points to a possible underlying condition that requires further exploration.
Explanation
Knee pain can be caused by several factors, including inflammatory conditions (like arthritis), overuse injuries, or other systemic issues. The swelling in your ankle and discomfort in your hands and hamstrings could indicate a broader inflammatory process, which is supported by your high sedimentation rate (indicating inflammation). The low hemoglobin and sodium levels might suggest other health concerns that could be contributing to your symptoms.
Next Steps
-
Keep a Symptom Diary: Track your pain levels, swelling, and any other symptoms you experience daily. Record what activities you did, foods you ate, and any potential triggers. This can help identify patterns or correlations.
-
Review Your Diet: Ensure you are eating a balanced diet rich in anti-inflammatory foods (fruits, vegetables, whole grains, lean proteins, and omega-3 fatty acids). Limiting processed foods and sugar can also help reduce inflammation.
-
Gentle Mobility Exercises: Engage in low-impact activities like swimming or cycling to promote circulation and maintain joint function without putting too much strain on your knees. Stretching gently can help improve flexibility and reduce stiffness.
-
Consult a Specialist: If you haven’t already, consider seeing a rheumatologist. They specialize in autoimmune and inflammatory conditions and may have further insights or tests to consider.
-
Pain Management Strategies: Use ice on your knees after activities to reduce swelling. Over-the-counter anti-inflammatory medications can help manage pain, but consult with a healthcare provider regarding their use, especially regarding any existing conditions or medications.
It's important to stay proactive about your health. Monitor your symptoms closely and explore these suggestions. Please feel free to reach out if you need further clarification or support!
Related Questions
Unexplained Red Swelling on My Arms?
Hello, I'm 23 years old and I've recently noticed that my forearms are becoming increasingly swollen and painful. This swelling seems to be expanding over time, which has me a bit worried. In the past, I experienced a smaller instance of this issue, and it resolved itself after about a week. Currently, the affected areas are very tender and hurt when I touch them. What could this be? Should I be concerned enough to seek immediate medical attention? Or might there be lifestyle adjustments I can make to address it? Thank you for any insights you can provide!
Exploring Solutions for Severe Sweating
I apologize if this comes out as a bit scattered; I’m writing quickly to express my thoughts and will refine it later for clarity. To summarize: I’m a 33-year-old man who experiences significant sweating during physical activity and in other situations where most people do not. The extent of my sweating is troubling. I perspire heavily during typical scenarios, and often find myself drenched in circumstances that would not warrant it for others. I genuinely believe I fall into the upper echelon—around the 90th percentile—of excessive sweaters. I can count on one hand how many people I’ve seen who sweat more than I do. To provide some context, I stand at 5 feet 9 inches tall and weigh 195 pounds. In my youth, I was quite athletic, playing soccer competitively through high school, where I graduated at around 135-140 pounds, and continued engaging in sports throughout college. Although the demands of adult life have impacted my fitness, I still consider myself fairly active. A year ago, I managed to complete a half marathon in 1 hour and 45 minutes, although my training has been sporadically hampered by injuries since then, and I’m currently averaging weekly runs of 10-15 miles. Additionally, I typically walk 2-3 miles nearly every day that I don’t run. My BMI measures at 29.1 with 24.7% body fat, but I recognize that these figures can be misleading. Given my history of strength training—consistent for about ten years before taking a break five years ago—I'm aware that muscle mass can skew these statistics. I estimate I could stand to lose around 25-30 pounds. This excessive sweating has significantly impacted my social interactions and day-to-day logistics. I often struggle with what to wear, need to bring extra clothes, and manage a higher laundry load. It can feel overwhelming to find places to dry my clothes before tossing them into the laundry. Staying hydrated is a constant concern—it's exhausting. I perspire copiously across my entire body; whether it’s my face, chest, back, arms, or legs. On days I exercise, I perspire so much that I would likely sweat comparably to someone running, even if I’m just walking. Temperatures above 60°F guarantee I’ll finish my run with soaking wet clothing. Just yesterday, while playing golf in 85°F weather, I had soaked through my shirt after merely hitting a few dozen balls during warm-ups. I felt mortified when heading back inside for more water. Any car rides through the summer almost ensure I’ll arrive with a drenched shirt, even with the air conditioning running comfortably. Occasionally, I'll find myself sweating while simply lounging on the couch, particularly when my partner or dog decides to snuggle. Nighttime is no respite either; I often wake up to a drenched pillow that feels unpleasant to rest on, unless I crank the air conditioning so low that it disrupts my sleep. Social gatherings cause me anxiety because I’m constantly concerned about my appearance and whether my clothing will leave me feeling self-conscious. Cotton shirts have become almost unwearable for me. I’m aware of certain factors that amplify my sweating, such as caffeine, hot drinks, spicy food, and alcohol. While my weight has compounded this issue, excessive sweating was a concern even during my peak fitness, estimated at 10-15% body fat. When I discuss my frustration with friends, they often respond with comments like "sweating is good for you," which feels dismissive and unhelpful. My research online indicates the primary medical solutions available are medications, Botox, or surgical procedures. I am reluctant to pursue the latter two options, and I would prefer not to add another prescription to the four I already take daily.
24/Male - Concern Regarding My Rear End
I frequently use butt plugs, and during a recent night, I decided to sleep with one in place. Upon waking, I experienced some mild discomfort, so I took it out. To my surprise, I discovered a small bump, which appeared to grow larger as the day progressed. The area has felt somewhat painful and mostly uncomfortable. I'm anxious about what this issue might be; could it be a hemorrhoid, or have I caused some injury? It’s been persisting for about 3 to 4 days now. I’m hesitant to visit a local doctor since I’d prefer to keep this issue private. I apologize for the directness of my inquiry, and I appreciate any insights or advice regarding whether I may have harmed myself. Thank you in advance for your help!
Experiencing Bleeding While on Birth Control Pills
I’m a 22-year-old woman, standing at 5'3" and weighing 115 pounds, with a medical background that includes anemia and heavy menstrual bleeding. This history prompted my doctor to prescribe Zovia, which I’ve been taking continuously. Approximately five years ago, I faced severe issues that required four blood transfusions and hospitalization due to my menstrual bleeding. Recently, however, I've encountered unexpected bleeding while still on the active pills. The bleeding seems irregular, transitioning from brown spotting to bright red blood, with occurrences of heavier flow. Just yesterday, I experienced a sudden gush, and now the flow has decreased to almost nothing. Alongside this, I'm dealing with typical menstrual symptoms such as breast tenderness, extreme fatigue, fluid retention, acne, and painful cramps. This condition has persisted for two weeks, causing me anxiety about my anemia potentially returning. Additionally, I want to clarify that I’m not sexually active, and haven’t been for over a year, so I can rule out pregnancy as a cause. I am seeking advice on how to manage or halt this bleeding. It appears to align closely with my usual menstrual cycle, and I'm apprehensive about taking a break from the pills. Last month, during the placebo week, the bleeding was so heavy that I had to use multiple full-length pads within just a few hours and endured significant pain. I only completed three days before restarting the active pills. My doctor has been unresponsive to my messages, which is incredibly frustrating. Any insights or suggestions on how to address this issue would be immensely helpful. Thank you!
Seeking Guidance for Severe Stomach Issues and Persistent Nausea
I’m a 20-year-old male struggling with debilitating stomach issues that have suddenly intensified over the last three months. The predominant symptom I’m facing is relentless nausea that lasts throughout the day; this sometimes leads to a gagging sensation and an increase in saliva production, though I don’t often actually vomit. Additionally, I feel a significant pressure and discomfort about 5 cm beneath my rib cage, which is sensitive to touch. My condition has resulted in excessive gas and frequent burping, typically starting around ten minutes after I eat. This has led to a 5 kg weight loss because my appetite is almost nonexistent. Oddly enough, I rarely feel hunger even though I am experiencing nausea, which doesn’t seem right to me. This situation has become overwhelming, negatively affecting my daily life and relationships, making it all the more urgent. I have a consultation scheduled with a specialist in two weeks, but my symptoms are escalating. I have undergone several medical tests, including an endoscopy, blood analysis, and a bowel ultrasound, all of which returned normal results. I’ve tried various medications such as Motilium, Itopride, and proton pump inhibitors, yet none have provided relief. The symptoms are unpredictable but tend to worsen with standing or walking, while sitting usually brings some improvement. Just today, I attempted some light exercise but ended up feeling quite unwell afterward, despite having no issues when exercising yesterday. I’ve looked into the possibility of small intestinal bacterial overgrowth (SIBO), though I’m unsure if it pertains to my case. To date, I have lost 5 kg in the last six months due to these issues. Has anyone else experienced similar problems? This persistent nausea is affecting my ability to function normally, and I’m desperately seeking to regain my previous health. Are there any strategies for managing these symptoms while I await treatment? The impact of this condition is driving me to the brink, and I’m struggling with significant discomfort every day. I’ve been on psychiatric medications for two years, so I don’t believe that’s contributing to my situation. I would greatly appreciate any insights or shared experiences that might help me cope during this challenging time.