Should I Seek Emergency Care? Concerns After MMR Vaccine
Hello. I’m a 29-year-old female weighing 100 pounds. I do not smoke, use drugs, or consume alcohol. I was vaccinated with the MMR (measles, mumps, rubella) shot 25 days ago. Shortly after, I found myself in the hospital due to pelvic inflammatory disease (PID). During my consultation, I mentioned my ongoing issues with frequent diarrhea and a history of respiratory infections. The doctor recommended several tests, including screenings for HIV and specific immunoglobulin levels (IgG, IgM, IgA). I proceeded with the HIV test, but chose to skip the others due to their high costs. The HIV result came back negative. A couple of days ago, I completed the additional tests, and the results were alarming, indicating critically low levels of IgG (35 mg/dl), IgA (3 mg/dl), and IgM (15 mg/dl). Now, with having received a live vaccine just over three weeks ago, I am anxious about the possibility of developing widespread measles. This situation is incredibly distressing, and I’m feeling quite overwhelmed. Is an immediate visit to the hospital advisable?
Answers (1)

8/16/2025, 8:31:05 PM
OpenHealth AI
It’s understandable that you're feeling overwhelmed given your recent health concerns and the tests you've undergone. Here, I’ll address your worries and provide guidance on what steps to take next.
Key Points:
- You have critically low immunoglobulin levels (IgG, IgA, IgM).
- You recently received the MMR vaccine, which contains live attenuated viruses.
- Your recent hospital visit for PID and symptom of ongoing diarrhea also adds complexity to your situation.
Explanation: The MMR vaccine is generally safe and effective, and while it is a live vaccine, the body's immune response typically protects against diseases like measles after vaccination. However, critically low immunoglobulin levels can impair your immune response, leaving you more susceptible to infections.
Low levels of immunoglobulins often indicate some form of immune deficiency. This condition can be caused by various factors, including chronic infections, medications, or autoimmune disorders. Your history of respiratory infections and current health issues may suggest that your body is struggling to mount adequate immune responses.
Next Steps:
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Contact Your Healthcare Provider: Given your low immunoglobulin levels and recent vaccination, it's crucial to connect with your healthcare provider immediately. Discuss your concerns about measles and ask specifically about the implications of your immunoglobulin levels related to your vaccination status.
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Monitor Symptoms: While waiting to speak with your healthcare provider, keep a close eye on any new or worsening symptoms, such as fever, rash, persistent diarrhea, or respiratory issues. Document these to share with your doctor.
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Consider Testing Follow-Up: Discuss options for further tests or treatments to address your low immunoglobulin levels with your healthcare provider. They may recommend immunotherapy or other interventions depending on the root cause.
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Evaluate Your Options: If you develop severe symptoms such as difficulty breathing, very high fever, or any signs of a widespread rash, seek immediate medical attention (consider emergency care).
Your health and peace of mind are essential. A proactive discussion with your healthcare provider can help clarify these issues and establish a plan tailored to your specific needs. Please remember that you are not alone in this; seeking support will help you navigate through these concerns.
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