Seeking Answers for Digestive Distress - Ongoing Struggles
My sister, at the age of 37, has been experiencing weekly bouts of nausea followed by vomiting, which culminate in excessive burping lasting several hours. Despite consulting with medical professionals and undergoing a range of examinations—including an upper endoscopy, several colonoscopies, stomach lining biopsies, and even swallowing a capsule camera for imaging—no concrete diagnosis has emerged. She attempted to track her food intake to pinpoint possible triggers but found it unhelpful; after eliminating various foods from her diet, she still saw no improvement. Additionally, she has a condition known as Eosinophilic esophagitis (EoE) for which she takes omeprazole daily to manage symptoms. Unfortunately, her healthcare providers have yet to recommend any additional testing, assuring her that everything appears normal. Frustrated and seeking clarity, she's eager for insights on potential causes of her symptoms so she can effectively advocate for herself in pursuit of answers. Any advice would be greatly appreciated! Thank you!
Answers (1)

8/16/2025, 1:51:04 AM
OpenHealth AI
It's understandable that your sister feels frustrated and anxious about her ongoing digestive issues. Weekly nausea, vomiting, and excessive burping can be very distressing, and the lack of a clear diagnosis after extensive testing is understandably disheartening. Here, I’ll outline some potential causes and suggest specific steps she can take to advocate for her health.
Main Points:
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Potential Causes: Given her existing condition of Eosinophilic esophagitis (EoE) and her symptoms, there might be several overlapping factors contributing to her distress. These could include:
- EoE exacerbations: Inflammation could still be contributing to her symptoms despite medication.
- Food sensitivities or intolerances: Other than EoE, she might have reactions to foods that are not typical allergens.
- Gastroesophageal reflux disease (GERD): Omeprazole helps with acid, but if her esophagus is irritated, further evaluation may be needed.
- Motility disorders: Issues with how food moves through the digestive tract can cause nausea and burping.
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Lifestyle Factors: Diet is crucial, but since traditional tracking hasn't helped, focusing on the timing of meals, portion sizes, and stress management might prove beneficial.
Next Steps:
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Nutritional Evaluation: Encourage her to work with a specialized dietitian familiar with Eosinophilic esophagitis. They can help develop a more tailored elimination diet or recommend specific foods to try gradually.
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Symptom Diary: She could keep a detailed symptom diary, not just focusing on what she eats, but also noting times of day, activity levels, and stressful situations that may correlate with her symptoms.
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Discussion with Healthcare Provider:
- Request additional tests or evaluations: Since current medications and previous tests haven’t resolved her symptoms, she might ask about a motility study or pH monitoring to assess how her esophagus is functioning.
- Explore other specialists: If her gastroenterologist hasn’t offered new insights, she could benefit from consulting an allergist or a specialist in gastroenterology who focuses on complex cases.
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Stress Management: If possible, she should incorporate stress-reduction techniques like mindfulness, yoga, or relaxation exercises since stress can exacerbate digestive issues.
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Research & Advocacy: Encourage her to gather information about her conditions and possible treatments. Sometimes, advocating for oneself or bringing research to a consult can lead to new approaches with healthcare professionals.
Overall, your sister deserves to find relief and clarity regarding her symptoms, and by being proactive about her health, she can take essential steps toward better management of her situation. Please let her know that it's perfectly fine to seek a second opinion if she continues to feel unanswered in her current care.
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