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Expert Opinion Requested on GP Diagnosis and Treatment

8/15/2025, 5:40:46 PMMale25-34

In 2021, I underwent a procedure where two stents were inserted into my arteries. Currently, my prescribed medications include Aspirin, Ramipril (1.25 mg each night and 2.5 mg in the morning), Bisoprolol (1.25 mg daily), Isosorbide Mononitrate (30 mg once a day), and Atorvastatin (80 mg at night). Approximately two weeks ago, I began experiencing intense hunger pangs. After evaluating my situation, my general practitioner monitored my weight, ordered a blood test, and requested that I provide weekly updates on my weight. The blood test results indicated a significant deficiency in vitamin D, leading to a prescription for Colecalciferol (20,000 units three times weekly) and Omeprazole (20 mg daily). Additionally, I was instructed to complete a stool analysis. During this period, I unexpectedly gained 10 kg within two weeks. The results from the stool test confirmed the presence of Helicobacter Pylori. In response, I was prescribed Amoxicillin (500 mg, two tablets twice a day) and Metronidazole (400 mg twice daily), along with an increase in my Omeprazole dosage to twice a day. Since initiating the antibiotic regimen, I have noticed a significant increase in my appetite. However, based on my research, I have found that most sources suggest that H. pylori infections typically result in weight loss, whereas I am experiencing weight gain. Is this an expected reaction during my treatment, or should I be wary of underlying issues?

Crohn's DiseaseThyroid DisordersInternal Medicine

Answers (1)

Cony

8/15/2025, 5:41:31 PM

OpenHealth AI

It's understandable to feel concerned about your sudden increase in appetite and weight gain while undergoing treatment for Helicobacter pylori (H. pylori) infection. Let's break this down into manageable parts to address your concerns.

Main Points

  • Weight gain during H. pylori treatment can occur, but it's not the most common response.
  • Increased appetite might be related to the antibiotics or other medications you are taking.
  • It's important to monitor your symptoms and discuss any significant changes with your healthcare provider.

Explanation

H. pylori infections are often associated with symptoms like abdominal discomfort, nausea, and sometimes weight loss; however, the treatment can affect individuals differently. Antibiotics such as Amoxicillin and Metronidazole may disrupt your gut flora, leading to changes in digestion and appetite. Additionally, Omeprazole (a proton pump inhibitor) reduces stomach acid, which can also influence how your body processes food.

Your prescribed medications, especially those that affect digestion and stomach acid, combined with a potential improvement in appetite due to a reduction in gastric discomfort from the H. pylori treatment, might explain why you are feeling hungrier. Also, vitamin D deficiency treatment can improve overall wellbeing, which might play a role.

Next Steps

  1. Track Your Symptoms: Keep a journal of your daily food intake, appetite changes, weight, and any other symptoms. This information can help clarify whether the increase in appetite is linked to your treatment.

  2. Healthy Eating: Focus on balanced meals rich in fruits, vegetables, lean proteins, and whole grains to manage your weight effectively while ensuring you receive necessary nutrients.

  3. Weight Monitoring: Continue to monitor your weight weekly as instructed by your GP. Be aware of any other changes (like feelings of fullness, changes in energy levels, etc.) that could be relevant.

  4. Consult with Your GP: If your increased appetite and weight gain persist or escalate, or if you experience any new symptoms, it’s crucial to discuss these changes with your general practitioner as soon as possible. They may want to evaluate your medication regimen, consider adding dietary advice, or check for any possible underlying issues.

Remember, while some aspects of treatment can lead to unexpected effects, many factors influence how our bodies respond to medication. Keeping an open line of communication with your healthcare provider is essential for managing your health effectively.

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