Is it Safe to Use Accutane with Seroxat and Seroquel Prior to Rhinoplasty?
I am presently on a regimen that includes Seroxat at a dosage of 25 mg (paroxetine) and Seroquel at 50 mg (quetiapine). With a rhinoplasty procedure approaching, my surgeon has recommended the use of Accutane (isotretinoin) beforehand to minimize oiliness and fat on my nose, given that I have notably thick skin in that area. However, I have reservations about potential drug interactions or side effects, particularly those that might affect my mood, as I am already receiving treatment for mental health issues. Has anyone experienced taking Accutane in conjunction with antidepressants or antipsychotic medications? Additionally, is it advisable to initiate Accutane shortly before undergoing surgery? (24 years old, weighing 72 kg, height 5'10")
Answers (1)
8/15/2025, 1:41:16 PM
OpenHealth AI
It's understandable to have concerns about starting Accutane (isotretinoin), especially in combination with your current medications, Seroxat (paroxetine) and Seroquel (quetiapine), prior to your upcoming rhinoplasty. Here’s a breakdown of the key points:
Main Points
- Potential Interactions and Side Effects: There is a risk of mood changes with Accutane, particularly if you're already managing mental health conditions.
- Timing of Accutane Use: Starting Accutane close to your surgery may influence healing and has implications for your overall recovery.
Explanation
Accutane is known to potentially cause mood swings, anxiety, and depression in some individuals, which can be a concern when combined with antidepressants like Seroxat. Additionally, both Accutane and the medications you're currently taking can have side effects that may complicate your surgical recovery. It's essential to be cautious when combining them, as any changes in mood or mental health symptoms can affect your overall well-being during this period.
Next Steps
-
Consult With Your Healthcare Providers:
- Discuss with both your prescribing doctor for Seroxat and Seroquel and your surgeon the possibility of using Accutane. Full transparency about your entire medication regimen is crucial for assessing potential interactions and side effects.
-
Assess Timing:
- Ideally, it may be advisable to initiate Accutane well in advance of your surgery to allow for monitoring any side effects that could impact your mood or recovery.
-
Monitor Your Mental Health:
- If you proceed with Accutane, keep a close eye on any changes in your mood or mental health. Consider a regular check-in on how you feel, especially during treatment and before surgery.
-
Healthy Lifestyle Choices:
- Maintain a balanced diet, stay well-hydrated, and manage stress through relaxation techniques or support systems during this time.
Your safety and mental well-being are paramount, so the collaborative approach with your healthcare team will be essential in making the best decision for your circumstances.
Related Questions
Stunted Growth Since Adolescence
At 19 years old, I stand at 5 feet 4 inches tall, and I have not seen any increase in my height since I was 12. I don't think I've experienced any nutritional deficiencies because I've been consistently working out at the gym twice a week and have been gradually gaining muscle. Therefore, I doubt I have a growth hormone issue. Could this situation be solely attributed to genetics? Or am I possibly just a late developer? Also, I've started to notice some acne over the past few months.
Spider Bite: A Cautionary Tale
Last weekend, from August 8th to 10th, I traveled to Oregon for a wedding and stayed in a basement-level AirBnB that had been refurbished. Upon arriving, I spotted a door that seemed to lead to a garage or storage area; it had noticeable gaps around its edges, allowing me to peek inside the locked space. The view revealed a clutter of gardening tools, old paint cans, abandoned cat supplies, and a thick layer of dust with cobwebs—quite reminiscent of a classic horror film’s eerie garage scenes. While I noted the oddity of the door, I soon put it out of my mind and continued enjoying the stay. Unfortunately, within the first day, I found myself removing two spiders from the place. My friend, terrified of one due to its size, decided to flush it down the toilet—another detail I made note of. Having lived in a basement myself before, I understood that spider encounters weren’t entirely unusual in such settings. Upon returning home to Seattle on August 10th, I reached into my friend’s car to grab a bag and noticed a sudden pain in my hip. After stepping inside, I found a bite mark that was slightly pink with a white center, leading me to suspect it was from a spider. The discomfort intensified, making it hard to lie on my right side, while my partner insisted it was simply a severe mosquito bite, considering my reputation for reacting dramatically to them. The next day, August 11th, the affected area had darkened noticeably and swelling became evident. The wound felt warm, prompting my anxiety to flare up. I decided to visit the doctor for an evaluation. After waiting for over two hours, I received a prescription for Cephalexin and Mupirocin Ointment but didn't have the chance to discuss my symptoms in detail with the physician. By the following day, August 12th, the pain had escalated and the heat emanating from the wound was alarming. Blisters began to form, popping and reappearing unpredictably. Following the instructions on my discharge paperwork regarding worsening symptoms, I ultimately made my way to the emergency room. At the ER, I was given Sulfameth/Trimethoprim and instructed to carry on with the antibiotics while keeping an eye on my symptoms. On August 13th, I didn’t visit the doctor despite experiencing sharp pains at the bite site; I simply focused on resting and sticking to my antibiotic plan. Later that evening, after a lengthy nap, I noticed a concerning red streak extending from the wound. I immediately contacted my primary care provider via MyChart, and they advised me to return to the clinic on August 14th. During my visit, I reported that both hot and cold compresses were painful and explained the significant swelling affecting my skin, which appeared to be dented in some areas. I expressed my discomfort that extended down my leg as well. However, the attending doctor, who wasn't my regular physician, dismissed my concerns as there was no visible discharge or fever, and suggested I let the antibiotics continue to work. She then outlined my wound with a used marker, stating that I should return if it spread. That evening, I began to feel a sore throat, my lymph nodes felt swollen, and my temperature rose to 99.4 degrees Fahrenheit. After reviewing my discharge instructions, I decided not to return to the clinic, not wanting to burden the medical staff with what I thought might be minor concerns. Upon waking on August 15th, I noticed a stiffness accompanying the pain in my leg, and the size of the wound had increased significantly. It felt hot, leaving me unsure of my next steps as I was still taking the prescribed Cephalexin and Sulfameth. Though I recognize I can be overly sensitive regarding my health, my past experiences—where my complaints weren’t taken seriously—continue to affect my caution. I once battled misdiagnoses leading to further complications, such as a severe kidney infection after being treated incorrectly for a mild UTI. That history has made me vigilant about my health. My mother has been adding to my worries; she often teases me for being dramatic over my health concerns. Ironically, when I expected her to minimize the situation, she encouraged me to seek help at the ER. I find myself wishing someone would assure me I don’t need to seek further medical attention, but I'm also seeking advice. What do you suggest I do? Thank you for reading my lengthy account of events.
Dealing with Impetigo on My Hands
I’m 43 years old, standing at 5'10" and weighing 270 pounds. The symptoms first started late the night before last. At present, I'm not on any medication, I don’t smoke, and I live with PCOS. My daughter showed signs of pink spots on her nose last Thursday. By Friday morning, those spots had transformed into red, moist patches, prompting us to seek medical attention. The clinic's Advanced Practice Nurse prescribed mupirocin, which we began using right away, and thankfully, her condition has improved significantly. However, I’ve since contracted the same infection, and I feel utterly embarrassed and unclean. I’ve been washing my hands consistently and disinfecting surfaces with Lysol spray and wipes throughout the house. As a result, my hands are now extremely dry, and I suspect the lack of gloves while using the wipes may have damaged my skin barrier, increasing my vulnerability. I now have lesions on my hands, nose, and mouth. I’ve started applying mupirocin that we had at home to treat myself. My hands and fingers are experiencing severe stinging and burning sensations and are covered in red bumps. Could this possibly be an adverse reaction to the mupirocin? I’ve reached out to my doctor, but as I’m not a long-time patient, I'm uncertain I’ll be able to see him today since the clinic closes at noon. Any guidance would be greatly appreciated as I'm unsure how to minimize the risk of spreading the infection while managing household chores like cooking and cleaning. My anxiety levels are skyrocketing, and I find myself wishing to retreat from it all…
Numbness in My Left Big Toe: Seeking Insights
Hello! I'm a 33-year-old female, standing at 5 feet 5 inches and weighing 156 pounds, and I’ve been dealing with a persistent numbness in my left big toe for the past year. This ongoing issue has begun to cause me a bit of concern. I don’t smoke, and my alcohol consumption is quite infrequent. I’m not diabetic and I regularly take care of the calluses on my feet, which I despise. Additionally, I have a history of Arthritis and Ankylosing Spondylitis that primarily impacts my hips and lower back. Alongside the numbness, there’s a brief burning sensation in the affected area that typically lasts between two to five minutes. I wear comfortable shoes and although I used to work in construction, which kept me fairly active, I still try to stay active when I can. Earlier this year, I had my appendix removed, although it turned out I never actually had appendicitis. Currently, I’m on a regimen of Sertraline (100mg) and NSAIDs to help manage my joint discomfort. My partner suspects the numbness might simply stem from my callous, but I’m not convinced since my other toe, which also has a callous, still retains sensation. I realize I should have consulted a doctor about this issue, but I haven’t yet taken that step. I would appreciate any insights or suggestions regarding this condition, as I would like to bring specific information to my healthcare provider.
Concerns Regarding My Undescended Testes (M27)
At the age of 27, I am dealing with a condition known as undescended testes. Notably, I have never experienced my testes fully descending into the scrotum; instead, they reside in the lower section of my groin, aligned with the base of my penis. I am seeking to understand the potential risks associated with this issue. I have epilepsy and Cushing's disease, which adds complexity to my health situation. Interestingly, I have never compared myself to other men regarding their testicular anatomy, so I remained unsure about what is considered normal in this regard. I recently underwent an ultrasound, and I'm currently awaiting the results. Previous medical professionals I consulted stated that my testes are positioned unusually high. Additionally, I had a pituitary tumor that went undetected for several years, severely impacting my hormonal balance throughout my life. This has resulted in ongoing erectile dysfunction characterized by weak erections and a lack of morning erections until recently, when I started testosterone replacement therapy (TRT). My libido has also been notably low. I suspect that my penis may not have reached its full growth potential, but since initiating TRT, I have noticed some improvement in size. Furthermore, due to having phimosis, I will be required to undergo circumcision in the near future.