Understanding Test Result Anomalies
Greetings, I’m a 30-year-old woman who recently underwent a metabolic panel. The findings revealed that my AST and ALT levels are nearly double what is considered normal. For the past two years, I had been misusing Unisom, taking between 16 to 20 pills daily. This revelation has left me extremely anxious, as I fear I may have caused significant harm to my liver. My last dosage was on July 10th, while the test occurred on July 30th. I do not consume alcohol, nor do I smoke. I have an appointment with my doctor on Tuesday to further address this issue. However, I am feeling increasingly scared. I have been experiencing substantial weight loss and fatigue, coupled with insomnia, which only adds to my anxiety. Is it possible that the test results could be inaccurate? Or am I simply worrying excessively without cause?
Answers (1)

8/15/2025, 3:40:58 AM
OpenHealth AI
It's understandable to feel anxious about elevated liver enzymes, especially with your history of Unisom misuse. Elevated AST (aspartate aminotransferase) and ALT (alanine aminotransferase) levels can indicate liver damage or stress. However, it's important to remember that these values can be influenced by various factors and don't always mean irreversible harm.
Understanding Your Situation:
- Liver Enzymes: AST and ALT are enzymes associated with liver function. Higher levels typically suggest the liver is stressed or damaged in some way, which can happen due to various reasons, including medication misuse.
- Unisom Misuse: Taking high doses of diphenhydramine (the active ingredient in Unisom) over an extended period could potentially affect your liver health. Liver enzymes can take time to return to normal after stopping potentially harmful substances.
- Symptoms: Weight loss, fatigue, and insomnia can stem from various physical and psychological issues. They can be related to your anxiety, the misuse of Unisom, or reflective of underlying health conditions that require further investigation.
Next Steps:
- Stay Calm and Informed: It's good that you have an appointment scheduled. Prepare for this by listing your symptoms, concerns, and questions. This will help you and your doctor evaluate everything effectively.
- Document Symptoms: Keep track of your weight loss, fatigue levels, and insomnia. This information will help your doctor assess any potential connections to your liver function.
- Hydration and Diet: Focus on maintaining a balanced diet rich in fruits, vegetables, whole grains, and lean proteins while avoiding any alcohol and processed foods that may further stress your liver.
- Manage Stress: Consider stress-reduction techniques such as deep breathing, meditation, or light exercise, which can help alleviate anxiety and improve your overall well-being.
- Follow Up Carefully: After your doctor's appointment, ensure to follow all recommendations and any further testing they suggest to get a clearer picture of your liver health.
While worrying is natural, many people do experience elevated liver enzymes that can improve with time and appropriate care. Stay proactive about your health, and don't hesitate to seek support from friends, family, or mental health resources if your anxiety feels overwhelming. You’re taking the right steps by acknowledging your concerns and seeking medical advice.
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