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High Ferritin with Low Iron Levels and Saturation

8/15/2025, 3:01:27 AMMale25-34

I am a 24-year-old female weighing 135 pounds, and I don’t consume alcohol or smoke. I have been experiencing a range of chronic health issues and have been seeking answers. Recently, I received some blood test results that revealed my ferritin levels to be at 230 ng/ml, iron levels at 30 mcg/dL, and iron saturation at 8%. For context, these values have changed slightly from two months ago when my ferritin was recorded at 220 ng/ml, my iron level was 95 mcg/dL, and saturation was 26%. My blood counts, including hemoglobin and platelets, fall within the normal range. Some of the symptoms I'm noticing include: - Frequent alterations in my bowel habits - Severe fatigue - Intense headaches - Sporadic swelling in my limbs - Periods of acute abdominal pain - Decrease in appetite I have also been prescribed Low Dose Naltrexone (LDN), but I have not yet gone to collect the medication. I’m curious if anyone has insight or theories regarding what these results and symptoms might indicate. Any advice would be greatly appreciated!

LupusFibromyalgiaCrohn's Disease

Answers (1)

Cony

8/15/2025, 3:02:14 AM

OpenHealth AI

You’re dealing with a complex situation characterized by high ferritin levels alongside low iron levels and saturation, along with several concerning symptoms. It’s important to approach this holistically.

Overview of Your Situation

  • High Ferritin: Ferritin is a protein that stores iron in the body. Elevated levels can indicate inflammation, infection, liver disease, or could be due to other factors.
  • Low Iron Levels and Saturation: This suggests that despite having stored iron (as indicated by high ferritin), your body may not be utilizing it effectively, which is unusual and worth investigating closely.
  • Symptoms: Your chronic fatigue, headaches, bowel habit changes, limb swelling, acute abdominal pain, and decreased appetite are significant and merit further understanding.

Possible Explanations

  1. Inflammatory Conditions: Conditions like lupus or Crohn’s disease can elevate ferritin due to inflammation while causing low iron due to chronic disease effects on absorption.
  2. Nutritional Issues: Malabsorption can lead to low iron levels, particularly with conditions affecting the gut.
  3. Other Conditions: There are various hematological or metabolic conditions that could lead to your symptoms and lab findings.

Next Steps

  1. Track Symptoms: Keep a detailed journal of your symptoms, noting when they occur in relation to your food intake, activity levels, and any medications or treatments you're undertaking—including when you start Low Dose Naltrexone.

  2. Hydration and Diet: Maintain good hydration and consider a balanced diet rich in fruits, vegetables, and lean proteins while discussing potential iron-rich foods or supplements with a healthcare provider who knows your medical history.

  3. Consider Food and Supplements: Explore if there's any dietary component that could improve your iron absorption, like pairing iron-rich foods (e.g., spinach, red meat) with vitamin C sources (like citrus fruits) to boost iron uptake.

  4. Discuss Further Testing: Given the complexity, consider discussing with a healthcare provider the need for further testing. This may include comprehensive assessments to check for inflammatory markers, vitamin deficiencies, or other underlying conditions.

  5. Follow Up on Medications: Once you collect the Low Dose Naltrexone, monitor how you respond to it, particularly regarding any changes in your symptoms.

  6. Stay Proactive with Healthcare: Keep in close contact with your healthcare team regarding these symptoms, especially if they worsen. Given the range of symptoms you’ve described, ongoing evaluation will be essential to finding the right treatment plan.

Please take care to monitor how you feel and make note of any exacerbations in your condition. Stay empowered in your health journey!

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