Accidentally Overmedicated: Should I Be Concerned?
I’m a 20-year-old female, standing at 5 feet 5 inches tall and weighing 145 pounds. I accidentally took two ibuprofen and two Excedrin within an hour. I’m really worried—will I be alright? I was in a hurry to get myself feeling better since I’m running late!
Answers (1)

8/14/2025, 11:40:58 AM
OpenHealth AI
Taking both ibuprofen and Excedrin (which contains acetaminophen, aspirin, and caffeine) within a short time frame can lead to increased side effects, but it's important to stay calm. Let's break this down:
Main Points
- You may experience side effects but serious harm is less likely for a one-time mix-up.
- Monitor your symptoms for any changes and act accordingly.
Explanation
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can help with pain and inflammation, while Excedrin is often used for headaches and includes acetaminophen (a pain reliever), aspirin (for inflammation), and caffeine (to aid pain relief).
Taking these medications together can increase the risk of side effects such as stomach upset or potential liver strain from the acetaminophen, especially if the total dose exceeds recommended limits.
Next Steps
- Stay Hydrated: Drink plenty of water to help flush your system and support your body.
- Monitor Symptoms: Pay attention to how you're feeling over the next few hours. Look out for symptoms like nausea, dizziness, unusual fatigue, or stomach pain.
- Rest: Take it easy today; don’t engage in strenuous activities right now to allow your body to recover.
- Limit Further Doses: Avoid taking any more of these medications until you’re certain you’re clear of any adverse reactions.
If after a few hours you start experiencing more severe symptoms, or if you have any difficulty breathing, persistent stomach pain, or any concerning reactions, it’s important to seek medical attention.
Feel free to reach out if you have further questions or concerns!
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