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Concerns Over NSAID Overconsumption in a 37-Year-Old

8/11/2025, 1:00:50 AMMale25-34

A 37-year-old male, standing at 5 feet 10 inches and weighing 220 pounds, is currently on a medication regimen that includes lurasidone and lamotrigine. Suffering from persistent migraines, he encountered a severe aura recently, leading to an impulsive decision. In a moment of panic, he consumed two tablets of Excedrin (each containing 250 mg of acetaminophen and 250 mg of aspirin), along with two Aleve (220 mg of naproxen each), and two ibuprofen (200 mg per tablet). In his misguided belief that using various medications would assist in alleviating his migraine, he now finds himself in distress, concerned that he may have overdosed on these pain relievers. He attempted to induce vomiting to relieve his anxiety, but was unable to expel anything. Although he suspects the situation might be manageable, possibly leading to an upset stomach, he remains anxious about the potential consequences of his actions. He recognizes that he may have acted recklessly and is seeking guidance on what steps to take next. Any recommendations would be greatly valued.

HeadacheJoint PainChronic Pain

Answers (1)

Cony

8/11/2025, 1:01:38 AM

OpenHealth AI

It's understandable to feel anxious after taking a higher dose of multiple pain relievers, especially given your migraine history. Here's a breakdown of your situation with actionable steps for managing your concerns.

Main Points:

  1. You’ve taken a combination of pain relievers that may exceed recommended doses, which can cause side effects.
  2. Immediate next steps include monitoring your symptoms and assessing any severe reactions.

Explanation:

You consumed:

  • Excedrin: 500 mg of acetaminophen and 500 mg of aspirin
  • Aleve: 440 mg of naproxen
  • Ibuprofen: 400 mg

Together, this totals a significant amount of pain relievers in a short time. Acetaminophen overdose can be especially harmful to the liver, while excessive use of NSAIDs (like ibuprofen and naproxen) can cause stomach issues, kidney problems, or increased bleeding risks.

Next Steps:

  1. Monitor Your Symptoms: Keep an eye on how you feel over the next few hours. Watch for signs of severe abdominal pain, nausea, vomiting, dizziness, drowsiness, or any unusual changes in your health.

  2. Stay Hydrated: Drink plenty of water to help flush your system. Avoid alcohol and caffeine, as these can potentially worsen the situation.

  3. Rest: Give your body time to recover. As much as possible, try to relax and avoid additional stressors.

  4. Avoid Taking More Pain Relievers: Until you assess how you’re feeling and whether you have any adverse reactions, do not take additional pain medications.

  5. Assess for Severe Symptoms: If you experience symptoms like severe abdominal pain, extreme drowsiness, confusion, or if you notice your skin or eyes turning yellow (a sign of liver distress), seek immediate medical attention.

  6. Follow Up: If you’re feeling better in a few hours, consider contacting a healthcare provider or pharmacist for advice about your medication use moving forward.

It’s crucial to remember you’re not alone in this, and worrying doesn’t change the situation. Taking steps to monitor your health and make informed decisions moving forward is key. If you're still concerned after monitoring your symptoms, reaching out for professional help would be appropriate.

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