Elevated Calprotectin Levels and Digestive Issues
Hello, For the past month, I've been experiencing abdominal pain. I underwent several tests, including blood work, stool examination, and a FIT test. While the results returned normal for the most part, my calprotectin level was notably high at 451. In addition to this, I have encountered several symptoms: - Intermittent discomfort in my stomach - Frequent urge to visit the restroom soon after meals - Significant pain on the left side below the ribs, which thankfully has been getting better - No presence of blood or mucus in my stool and no vomiting - My diet has become quite limited, as I can only tolerate bland foods My doctor has prescribed 20mg of lansoprazole to help manage my symptoms, but I am contemplating whether I should advocate for further investigations. I have some concerns that the issue could signify a more serious condition, yet the cost of a colonoscopy is a worry. As a male in my late 20s, I’m eager to know what steps I might take next and what potential conditions could be causing these symptoms. Thank you for your assistance!
Answers (1)

8/10/2025, 10:20:42 AM
OpenHealth AI
Thank you for sharing your concerns. Elevated calprotectin levels, especially combined with your symptoms, suggest inflammation in the intestines, but there are various potential causes. Your symptoms might indicate conditions such as inflammatory bowel disease (IBD), infections, or even functional gastrointestinal disorders. It's comforting to know that you have already done many necessary tests, and I encourage you to prioritize managing your symptoms and gaining clarity on your condition.
Explanation
Calprotectin is a protein found in white blood cells, and it's often elevated when there's inflammation in the intestines. While your symptoms and the elevated calprotectin level indicate ongoing gastrointestinal issues, the absence of blood and mucus in your stool is a positive sign. Your recent treatment with lansoprazole indicates a focus on potential acid-related issues, and it can help reduce stomach discomfort.
Next Steps
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Monitor Your Symptoms: Keep a detailed record of your abdominal discomfort, urge to use the restroom, and any changes in your bowel habits. This can provide useful information for any future discussions with your healthcare provider.
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Diet Management: Since you've mentioned that you can only tolerate bland foods, focus on incorporating easy-to-digest options like bananas, rice, applesauce, and toast (the BRAT diet) temporarily. Keep hydrated, and consider smaller, more frequent meals.
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Take Lansoprazole as Prescribed: Follow your doctor's instructions for the medication to help manage stomach acid and symptoms. Monitor how you feel on this medication and note any improvements or ongoing issues.
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Consider Follow-Up Tests: If symptoms persist or worsen (e.g., increased pain, significant changes in bowel habits), be proactive in discussing further investigations with your doctor. While cost is a concern, there are often options for financial assistance or community health programs.
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Explore Stress Management Techniques: Anxiety about your health can worsen symptoms. Practices such as deep breathing, meditation, or gentle yoga may help alleviate some discomfort and improve your overall sense of well-being.
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Stay Informed and Supported: Connect with support groups for people with digestive issues. Sharing experiences could provide both insight and emotional support.
If you start noticing new symptoms or significant changes, don't hesitate to ensure timely medical advice. You're taking the right steps by being attentive to your health; continue to advocate for yourself as appropriate. Please let me know if you have further questions or need more guidance!
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