Elevated MCHC and MCH Levels
A 19-year-old male recently underwent a blood examination, and the findings have raised some concerns. The report indicated that his MCHC (Mean Corpuscular Hemoglobin Concentration) stood at an unusually high 59.6 g/dL, while the MCH (Mean Corpuscular Hemoglobin) was reported at 52.3 pg. Both of these values are alarmingly elevated. Additionally, the results revealed that he is experiencing anemia, with red blood cell (RBC) count at 2.67 million cells per microliter and hematocrit (HCT) percentage at 24%. His folate level was noted to be 3.2 μg. He’s seeking advice on potential next steps and is questioning the reliability of these lab results; could there be a mistake, or are the findings genuinely troubling? Furthermore, it’s worth noting that his thyroid-stimulating hormone (TSH) level is elevated at 4.76 mIU/L, while his vitamin B12 level remains within the normal range at 657 ng/L, and his iron level is recorded at 38 μg.
Answers (1)

8/9/2025, 2:01:59 AM
OpenHealth AI
The lab findings you've shared indicate several important factors that require attention. The elevated MCHC and MCH levels are unusual, and combined with the anemia and other values, they suggest there could be underlying conditions to explore further.
Explanation
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MCHC and MCH: These values reflect how much hemoglobin is in your red blood cells. High levels could suggest conditions like hereditary spherocytosis or dehydration but require further evaluation, especially in the context of existing anemia.
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Anemia: The low RBC count (2.67 million) and hematocrit percentage (24%) indicate anemia, which can result from various causes including nutritional deficiencies (like folate or iron, though your iron seems low but still in the acceptable range).
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Folate and Vitamin B12: While your B12 is normal, the folate level appears borderline low. Folate is crucial for healthy red blood cell production.
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TSH Level: An elevated TSH suggests that your thyroid may not be producing enough hormones, which can also contribute to fatigue and symptoms that overlap with anemia.
Next Steps
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Confirm Results: Given the abnormal values, it's essential to confirm these results with repeat blood tests. Minor lab errors can occur, so it is wise to check.
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Dietary Assessment: Ensure you are consuming a balanced diet rich in iron (red meat, beans), folate (leafy greens, legumes), and adequately hydrated to support blood health.
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Monitor Symptoms: Keep track of any symptoms you may be experiencing, such as fatigue, dizziness, or shortness of breath, as these can help clarify the need for urgency.
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Follow-Up Testing: Talk about scheduling a follow-up with your healthcare provider to discuss these findings. You might need additional tests, like a reticulocyte count, to assess how well your body is producing red blood cells, and possibly tests to check your iron stores (serum ferritin).
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Thyroid Function: Explore if there are symptoms suggesting hypothyroidism (like fatigue, cold intolerance, or weight changes), since treatment may be needed based on your elevated TSH.
By addressing these actionable steps and monitoring your health, you can move towards clarifying these concerning results and improve your well-being. If you have further questions or concerns, feel free to ask!
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