Seeking Guidance on Health Concerns for 12-Year-Old Girl
Greetings everyone, I am reaching out for some expert advice regarding a 12-year-old girl who has been facing several alarming health challenges over the past few months, and unfortunately, the local physicians have not been able to provide adequate help. After she took ibuprofen (Ardil), she experienced two instances of severe cold sweating and a drastic drop in body temperature, reaching as low as 34°C. Both episodes occurred within an hour of taking the medication; the latest one happened today. During these incidents, she appeared very pale, was excessively sweaty, and had noticeably cold skin, necessitating immediate warming. Additional health issues she is contending with include: - An extreme lack of appetite, resulting in nearly no food intake - Rapid weight loss occurring over the last several weeks - Ongoing stomach pain and a prior diagnosis of gastric inflammation - Significant sweating that is particularly pronounced at night or following minimal physical exertion - Occasional burning sensation while urinating, noted once in the previous week - Deteriorating dental health and a delay in the eruption of her upper lateral incisors - Persistent fatigue and weakness Though her doctors have prescribed various medications, they have not conducted thorough diagnostic tests like lab work or imaging studies. According to her mother, while the initial blood tests came back "normal," no further examinations (such as for Helicobacter pylori or potential endocrine or autoimmune disorders) have been pursued. Is it possible that she might be experiencing an allergic or systemic reaction to the ibuprofen? Or might there be a more serious underlying condition related to metabolism, gastrointestinal health, or endocrine function that has yet to be identified? Any recommendations regarding appropriate tests or specialist consultations would be immensely helpful. Thank you for your assistance.
Answers (1)

8/7/2025, 1:02:32 AM
OpenHealth AI
It sounds like you're understandably concerned about your 12-year-old daughter's health, given her troubling symptoms and the response from local physicians. Let's break this down and outline some important considerations and actionable next steps.
Main Points
- The severe reactions following ibuprofen use may indicate an adverse effect or allergy.
- Multiple concerning health issues, including lack of appetite, unexplained weight loss, and other symptoms, warrant thorough investigation.
- Further diagnostic testing is crucial to identify any underlying conditions.
Explanation
The symptoms your daughter is experiencing could potentially be related to her use of ibuprofen, especially since her body temperature dropped significantly and she displayed signs of acute distress such as cold sweating and pallor. These reactions could be allergic or systemic, but also point toward a possible metabolic, gastrointestinal, or autoimmune issue, especially given the other symptoms you've mentioned.
Her extreme lack of appetite and rapid weight loss are particularly alarming. A lack of sufficient nutrition can lead to various health complications, while her ongoing stomach pain and urinary burning sensation may suggest underlying gastrointestinal or urinary tract issues. Additionally, the fatigue and poor dental health present a broader picture that needs to be addressed.
Next Steps
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Immediate Monitoring:
- Keep a close observation of her symptoms, especially any instances of severe reactions after taking medications. Document these occurrences, including timings, duration, and other accompanying symptoms.
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Consult a Specialist:
- Seek a referral to a pediatric gastroenterologist. Given her symptoms, they can perform more targeted assessments related to both her gastrointestinal and potential metabolic health.
- A referral to an endocrinologist may also be warranted to rule out any hormonal or metabolic disorders.
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Request Comprehensive Testing:
- Ensure that further extensive lab work is done, potentially including:
- Blood tests for infections (e.g., Helicobacter pylori).
- Endocrine function tests to assess hormone levels.
- Complete blood count (CBC) and metabolic panel.
- Consider abdominal ultrasound or endoscopy for direct visualization of the gastrointestinal tract if recommended by the gastroenterologist.
- Ensure that further extensive lab work is done, potentially including:
-
Nutritional Evaluation:
- Consult with a dietitian who specializes in pediatric care, who can help assess her nutritional intake and suggest safe, palatable food options tailored to her preferences and tolerance.
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Evaluate Medications:
- Discuss with her physician or a pharmacist whether she should avoid ibuprofen and what alternative pain management strategies could be used without adverse effects.
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Emotional Support:
- Consider mental health support for both her and your family, as prolonged health issues can be stressful. Counseling may help her cope with these challenges.
Conclusion
The combination of symptoms you're describing is complex, and it's essential for her health to proceed with careful, detailed investigations. Trust your instincts as a caregiver, and pursue the specialist consultations and testing needed to ensure she receives appropriate care. Remember, you know your daughter best, and advocating for her health is vital.
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