Distinguishing Between Melanoma Recurrence and Typical Scar Alterations
At 43 years of age, I was diagnosed with stage 0/in situ melanoma on my right lower extremity in March 2022. Following two surgical procedures—initially for removal and later for flap closure—I experienced a persistent wound that took nine months to heal, necessitating visits to a specialized clinic and the application of a vacuum-assisted closure. I suspect that this slow healing process was influenced by my medication for chronic myeloid leukemia, Sprycel, which is known to cause such delays. Recently, I've noticed a red mark forming right over the original melanoma site in the past couple of weeks. With a dermatology appointment scheduled for tomorrow, I'm contemplating whether I should request a biopsy or if this could simply be typical changes in the scar. Photos will be shared in the comments for reference.
Answers (1)

8/6/2025, 4:40:47 PM
OpenHealth AI
It's understandable to be concerned about changes at a previous melanoma site, especially after your past diagnosis and treatment. The red mark you're noticing could be a common scar alteration or a sign that warrants further evaluation. Given your medical history and the potential impact of your current medication, it's wise to approach this carefully.
Key Points:
- Changes at a scar site can be normal, but they may also indicate a recurrence of melanoma or other issues that need attention.
- Your history of melanoma and the fact that you're on medication that can affect healing make it important to evaluate changes thoroughly.
Explanation: Scar tissue can undergo changes over time, leading to redness or other alterations. However, due to your previous stage 0 melanoma diagnosis, it's prudent to take any new changes at the site seriously. Redness and other symptoms can arise from various factors, not just cancer recurrence. Additionally, medications like Sprycel can influence healing, making your situation more nuanced.
Next Steps:
- Discuss Your Concerns: During your dermatology appointment, openly share your recent observations and your past medical history, including the slow healing attributed to Sprycel.
- Request a Biopsy: If the dermatologist feels it is necessary based on your examination, express your preference for a biopsy to rule out any serious concerns, especially given your melanoma history.
- Monitor the Area: Until your appointment, continue to observe any changes in the red mark, such as size, color, or any other symptoms like itching or bleeding.
- Documentation: Take clear photos of the area to track changes over time, which may assist the dermatologist in evaluating your situation.
It's great that you have an appointment scheduled soon, and discussing these concerns with a specialist is a constructive step forward. You're actively managing your health by addressing this potential issue—keep that focus as you move ahead!
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