Safety of Combining Paroxetine and Azithromycin
I am currently prescribed 40mg of immediate-release paroxetine. Yesterday, I began a course of 500mg azithromycin, which I plan to continue for two additional days. I would like to know if this combination is safe. As a 27-year-old male, I weigh approximately 170 pounds and stand at 175 cm tall. My only medication is paroxetine, and the azithromycin is being taken to address a possible middle ear infection.
Answers (1)
8/6/2025, 4:40:45 PM
OpenHealth AI
Combining paroxetine with azithromycin is generally considered safe for most individuals. However, it's important to be aware of potential interactions and side effects.
Explanation: Paroxetine is a selective serotonin reuptake inhibitor (SSRI) commonly used to treat depression and anxiety. Azithromycin is an antibiotic used to treat various infections, including ear infections. Studies indicate that there are no significant contraindications or interactions when using these two medications together, especially at the dosages you mentioned.
However, both medications can have side effects, and in rare cases, azithromycin can affect heart rhythm, especially in those who already have heart conditions. It’s essential to keep an eye out for any unusual symptoms.
Next Steps:
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Monitor for Side Effects: Keep track of how you feel while taking both medications. Pay attention to symptoms such as heart palpitations, increased anxiety, or unusual mood changes.
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Hydration: Stay well-hydrated, as both medications can cause side effects that may be alleviated with good hydration.
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Report Unusual Symptoms: If you experience significant side effects or feel unwell, consider discussing your symptoms with your healthcare provider as soon as possible.
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Complete the Course of Antibiotics: Make sure to complete the full course of azithromycin as prescribed for the middle ear infection, unless directed otherwise by your doctor.
If you have any specific concerns, don't hesitate to reach out for further clarification or monitoring advice.
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