Elevated AST and ALT Levels in Blood Tests
Greetings, I am a 35-year-old male who recently underwent a routine physical examination. During this check-up, the tests revealed elevated levels of AST and ALT in my blood work. Could anyone provide insights into what might cause these elevated readings? Additionally, I would appreciate any advice on steps I can take to return these levels to normal. Thank you for your assistance!
Answers (1)

8/6/2025, 1:31:17 PM
OpenHealth AI
Elevated AST (aspartate aminotransferase) and ALT (alanine aminotransferase) levels often indicate liver stress or damage. This can occur due to various reasons such as liver diseases, fatty liver, alcohol use, certain medications, or even strenuous exercise.
Explanation: Both AST and ALT are enzymes found primarily in the liver, and when the liver is damaged or inflamed, these enzymes can leak into the bloodstream, causing elevated levels. Some common causes of elevated AST and ALT include:
- Fatty Liver Disease: This is one of the most common reasons, often related to obesity, diabetes, or high cholesterol.
- Alcohol Consumption: Excessive alcohol intake can harm the liver.
- Medications: Certain medications, including over-the-counter drugs like acetaminophen, can affect liver function.
- Viral Hepatitis: A viral infection can cause inflammation of the liver.
- Other Conditions: Conditions like autoimmune diseases, muscle disorders, or metabolic disorders may also lead to elevated liver enzymes.
Next Steps:
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Lifestyle Changes:
- Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Limit saturated fats and sugars. Avoid processed foods, which can worsen liver function.
- Hydration: Drink plenty of water each day to support liver health.
- Alcohol Reduction: Avoid alcohol or significantly reduce intake to help your liver recover.
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Exercise: Regular physical activity can help manage weight, reduce fat in the liver, and improve overall health. Aim for at least 150 minutes of moderate exercise weekly.
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Weight Management: If you're overweight, losing even a small percentage of your body weight can improve liver health.
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Review Medications: Make a list of any medications (prescription or over-the-counter) and discuss them with a healthcare professional to see if they might affect your liver.
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Follow-Up: Monitor your levels in a follow-up blood test to see if lifestyle changes are effective. Keeping track of any symptoms, like fatigue or abdominal discomfort, can also provide useful information.
If your symptoms worsen or if you have concerns about other symptoms like jaundice or abdominal pain, it may be necessary to seek professional medical advice for further evaluation. Let me know if you need more details on any specific action!
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