Concerns Over Lab Results
Height: 5'2; Weight: 92 lbs; Age: 18F. I’ve been experiencing troubling gastrointestinal symptoms, including abdominal discomfort, bloating, gas, constipation, and diarrhea. I don’t smoke or drink alcohol. I have been diagnosed with Postural Orthostatic Tachycardia Syndrome (POTS). Around a year ago, I received a diagnosis of mild gastroparesis following a gastric emptying study (GES). Recently, I underwent another GES which indicated that the gastroparesis had improved, yet my symptoms remained. Therefore, my gastroenterologist recommended proceeding with an esophagogastroduodenoscopy (EGD). I visited my doctor yesterday to discuss the biopsy results from my EGD, and they indicated that the findings were largely normal. I was diagnosed with mild gastritis and prescribed Omeprazole, in addition to being told I have a mild lactose intolerance. However, while reviewing the lab report out of curiosity today (I find them quite interesting), I noticed that my lactase level wasn't the only abnormal finding in the disaccharidases panel. The report also noted moderate to severe reductions in the activity levels of alpha-glucosidase. Here are my specific enzyme levels: - Lactase: 7.3 U/g (Reference interval: >=10.0) - Maltase: 43.6 U/g (Reference interval: >=100.0) - Palatinase: 3.6 U/g (Reference interval: >=9.0) - Sucrase: 7.3 U/g (Reference interval: >=25.0) Could these low enzyme levels indicate something significant? I'm hesitant to bring this up with my doctor, as they suggested that my symptoms might be idiopathic or related to stress, and I don’t want to appear as if I’m questioning their judgment or seeking an unnecessary diagnosis. Trust me, I dislike having to play the role of a doctor, but I can’t shake the feeling that something might have been overlooked. I completely understand if this is just a minor detail that doesn't really impact the bigger picture of my health!
Answers (1)
8/6/2025, 12:31:19 AM
OpenHealth AI
It's completely understandable to feel concerned about your lab results, especially when they reveal abnormal enzyme levels alongside ongoing gastrointestinal symptoms. Your inquiry highlights the desire for clarity on how these results may impact your health and if they indicate something significant.
Key Points:
- Low Enzyme Activity: Your disaccharidase panel shows low levels of lactase, maltase, palatinase, and sucrase, which can contribute to gastrointestinal symptoms such as bloating and discomfort.
- Gastroparesis and POTS: Your existing conditions (gastroparesis and POTS) complicate your symptoms and may interact with digestive health.
- Understanding Your Results: It’s important to understand the implications of these enzyme levels and how they relate to your symptoms.
Explanation:
The disaccharidase enzymes (lactase, maltase, sucrase, and palatinase) are crucial for digesting certain carbohydrates found in food. Low levels of these enzymes can lead to issues like malabsorption, which means your body may not be able to properly digest and absorb nutrients. Given your mild lactose intolerance and low enzyme levels, it's possible these could contribute to your gastrointestinal distress. However, your doctor may have determined the primary cause of your symptoms relates more to gastroparesis, stress, or idiopathic factors.
Recommended Next Steps:
- Keep a Symptom Diary: Note your symptoms, dietary intake, and any patterns you observe. This can help you and your doctor better understand your situation.
- Consider Dietary Adjustments: Given your lactose intolerance and low enzyme levels, a temporary trial of a low-FODMAP diet or consulting a registered dietitian may help identify dietary triggers for your symptoms.
- Communicate with Your Doctor: Schedule an appointment to discuss your concerns and the lab results. Transparency is crucial, and expressing your feelings may lead to a more collaborative approach in managing your digestive health.
- Monitor Symptoms: If your symptoms worsen or new symptoms develop, make sure to seek medical advice promptly.
Remember, your concerns are valid, and it's important to advocate for your health while maintaining a partnership with your healthcare provider. You're not questioning their judgment—instead, you're actively participating in your healthcare, which is beneficial!
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