Ongoing Infection or Something Else?
At 34 years old and generally in decent health, I've found myself struggling to maintain a workout routine and properly care for my well-being for more than a month now. Standing at 5’9” and weighing 195 pounds, I do not suffer from any chronic conditions or take regular medications. For over a month, I've been grappling with what seems to be an infection, and I am becoming increasingly disheartened. The initial symptoms surfaced the week leading up to the 4th of July, which included congestion, mucus production, overwhelming fatigue, a persistent wet cough, and various body aches. Five weeks have passed since those initial signs emerged. I sought help at an urgent care facility, where I was prescribed a combination of amoxicillin clavulanate and prednisone. While the prednisone provided some relief, I began to feel unwell again once I completed the course. Returning to urgent care, I was given doxycycline and prednisone again; once more, I experienced temporary improvement but deteriorated again after finishing the medication. Just this week, I revisited urgent care for a chest X-ray, and the nurse practitioner informed me that I was dealing with lung inflammation. Unfortunately, my condition has worsened. I now experience shortness of breath (I start coughing after only a few sentences), significant fatigue, and tender, swollen lymph nodes in my neck. Initially, I felt soreness on the left side of my neck and throat, which has now shifted to the right side, making that area painful as well. Could it be that I'm developing resistance to the antibiotics? I plan to return to urgent care in the morning to request blood tests and a throat culture. Two weeks ago, I tested negative for Covid-19, influenza, and strep throat.
Answers (1)

8/2/2025, 1:40:53 AM
OpenHealth AI
It sounds like you're going through a challenging and frustrating time with your health, and it’s understandable to feel disheartened with ongoing symptoms. Given the duration of your issues and the medications you've tried, it's crucial to reevaluate what's happening with your body.
Key Points:
- Your prolonged symptoms suggest a persistent issue possibly involving lung inflammation or a secondary infection.
- The shortness of breath and swollen lymph nodes may indicate that further investigation is warranted.
- It's wise to request blood tests and a throat culture, as you've planned for your upcoming urgent care visit.
Explanation:
Your symptoms—persistent cough, fatigue, shortness of breath, and swollen lymph nodes—could be related to several factors. While antibiotic resistance is a concern, your ongoing symptoms could also suggest:
- A viral infection that isn’t fully resolving.
- An underlying condition such as allergies or asthma exacerbating inflammation.
- A secondary bacterial infection or a non-infectious inflammatory response.
Taking antibiotics repeatedly can lead to changes in bacteria, but it doesn't always mean resistance. Sometimes, the infection may not respond to the first-line treatment, requiring a different approach or further testing to identify the exact cause.
Next Steps:
-
Return to Urgent Care: Ensure you discuss your ongoing symptoms, the need for blood tests, and a throat culture, which will help rule out any other infections. Specifically, mention your lymph node tenderness and shortness of breath.
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Monitor Symptoms: Keep a daily log of your symptoms, noting any changes, severity, and what seems to trigger or relieve them. This information will be helpful for your healthcare provider.
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Hydration and Rest: Focus on staying hydrated and getting ample rest. Engage in light activities as tolerated to avoid overexertion, which can exacerbate fatigue and shortness of breath.
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Consider Allergies or Asthma: Based on your symptoms, discuss with your provider the possibility of allergies or asthma, which could cause similar respiratory symptoms and require a different treatment approach.
Remember, it's okay to seek a second opinion if your symptoms do not resolve or if you have concerns about your treatment plan. Your persistence in seeking care is important, and addressing these ongoing health challenges will help you get back on track with your well-being. Let me know if you need further clarification or support!
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