Post-Surgery Nicotine and Psychedelics Usage: What to Know
At 26 years old, weighing 62 kg and measuring 172 cm, I am a Caucasian female who is prescribed promethazine to help with insomnia. Having recently undergone a minor surgical procedure, I am keenly focused on reducing any scarring that may result. In anticipation of the surgery, I refrained from using nicotine, cannabis, and psychedelics for a month. I have also steered clear of exposure to secondhand smoke, as I do not smoke myself. Though I am on the mend, my recovery is not yet complete, but I expect the wound to seal completely in the near future. I am curious about the potential implications of reintroducing nicotine, cannabis, or psychedelics into my routine once my wound has healed. Could these substances negatively influence the healing process or lead to more pronounced scarring over time? Minimizing the appearance of scars is my top priority, and in addition to avoiding these substances, I am currently applying a silicone cream to aid in the healing process.
Answers (1)
8/1/2025, 7:20:51 PM
OpenHealth AI
It's great to see your commitment to healing and minimizing scarring after your surgery. When considering the potential impacts of reintroducing nicotine, cannabis, or psychedelics into your routine, it’s important to understand their effects on healing and skin health.
Summary of Key Points:
- Nicotine: Can constrict blood vessels, potentially reducing blood flow to healing tissues and making scarring worse.
- Cannabis: Effects can vary. Smoking cannabis can introduce irritants similar to tobacco smoke, which may delay healing. Edibles may have fewer effects on healing but could still pose risks depending on individual responses.
- Psychedelics: While limited research exists regarding their impact on surgical healing, these substances generally do not show direct links to increased scarring.
Detailed Explanation:
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Nicotine: Smoking or using nicotine products can limit blood circulation, which is critical for wound healing. This could lead to more pronounced scarring. In studies, nicotine has been shown to negatively affect regeneration and healing processes in the skin.
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Cannabis: Although some may believe cannabis has healing properties, smoking it can lead to additional irritation, much like tobacco. This may delay the recovery of your surgical site and could hinder your efforts to minimize scarring. If you choose to use cannabis, consider non-smoking methods (like edibles or oils) to potentially mitigate damage.
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Psychedelics: Substances like psilocybin or LSD have limited direct evidence regarding physical wound healing but can impact mental health, which is crucial during recovery. Stress reduction and mental well-being are important for overall health and healing, so use caution with substances that might alter your mental state during this critical period.
Next Steps:
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Continue Avoiding Nicotine: Prioritize staying away from nicotine in any form to support optimal healing and scar management. Consider delaying its reintroduction indefinitely if possible.
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Consider Timing for Cannabis: If you decide to use cannabis, wait until your wound has fully healed, and opt for non-smoking methods to minimize irritation.
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Limit or Postpone Psychedelic Use: It's advisable to refrain from psychedelics during your recovery phase until you have fully healed, both physically and mentally.
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Keep Using Silicone Cream: Continue applying silicone cream as it is known to help with scar formation effectively. Consistency with this treatment is key during your healing process.
Taking these steps will significantly boost your recovery and scarring minimization efforts. Allow yourself time to heal fully before making decisions about reintroducing any substances. Let me know if there's anything else you'd like to know!
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# 7-Month-Old Child with Abernethy Malformation - Exploring Treatment Options ## [7-Month-Old] Identified with Abernethy Malformation (Congenital Portosystemic Shunt) - Treatment Methods? **Age:** 7 months **Gender:** Female **Height:** Age-appropriate **Weight:** Currently 9 kg, was 2.8 kg at birth **Ethnicity:** Asian **Duration of Symptoms:** Present since birth **Location:** Uzbekistan **Pre-existing Health Issues:** Abernethy malformation (congenital portosystemic shunt), liver hemangiomas, chronic jaundice, anemia **Current Treatments:** Supportive management --- ## INITIAL PRESENTATION (June 2025 - July 2025) Our daughter arrived on **June 27, 2025**, presenting with: - Birth weight: **2.8 kg** - Marked jaundice (yellowing of skin and sclera) - Pale or clay-colored stools - **Bilirubin level: 245 μmol/L** (typically <20) An immediate ultrasound indicated multiple liver anomalies, initially thought to be hemangiomas. --- ## FIRST COMPREHENSIVE ASSESSMENT (August 1, 2025 - 1 Month Old) ### Multislice Computed Tomography (MSCT) with 3-Phase Contrast (August 1, 2025): **RESULTS:** - **Portocaval shunt size: 9.9 mm** (blood bypassing the liver into the inferior vena cava) - **Arteriovenous shunt size: 4.4 mm** - **Portal vein size: 6.1 mm** (patent) - **Three nodular cystic lesions** located in the perivascular area, with largest measuring 11.6×20.7 mm, enhancing during the venous phase - Liver features a heterogeneous architecture, exhibiting irregular enhancement - Gallbladder appears elongated and slightly enlarged - Other abdominal organs exhibit normal findings **RADIOLOGIST’S ASSESSMENT:** "Congenital portosystemic shunt indicative of Abernethy malformation; less likely arteriovenous malformation (AVM); cannot dismiss the possibility of localized liver lesions." **ADVICE:** Seek consultations with an abdominal and vascular surgeon. ### Blood Tests (August 1, 2025): **Complete Blood Count:** - WBC: 10.44 × 10⁹/L (normal range) - **RBC: 2.1 × 10¹²/L** (LOW - indicating severe anemia) - **Hemoglobin: 69 g/L** (CRITICALLY LOW; normal is 117-166) - Platelets: 403 × 10⁹/L (elevated) **Biochemistry Analysis:** - 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WBC: 5.8 × 10⁹/L (SHOWS IMPROVEMENT) - **RBC: 2.93 × 10¹²/L** (IMPROVED but still low) - **Hemoglobin: 72 g/L** (SHOWS IMPROVEMENT but still low) - Platelets: 223 × 10⁹/L (BACK TO NORMAL) - Neutrophils: 30.0% - Lymphocytes: 64.8% - Monocytes: 4.6% ### Biochemistry (January 28, 2026): - Total protein level: 67 g/L (slightly deficient) - Creatinine: 20.7 μmol/L - **Total Bilirubin: 242 μmol/L** (STILL HIGH - unchanged) - **Direct Bilirubin: 142 μmol/L** (VERY HIGH) - **ALT: 50 IU/mL** (DRASTICALLY LOWER from >1000!) --- ## OVERVIEW OF PROGRESS OVER 6 MONTHS | Parameter | August 2025 | January 2026 | Change | |------------------|-------------|---------------|--------------------------| | **Hemoglobin** | 69 g/L | 72 g/L | ↗ Slight improvement | | **RBC** | 2.1 | 2.93 | ↗ Improved | | **ALT** | >1000 | 50 | ✓✓ MAJOR IMPROVEMENT | | **Bilirubin** | 245 | 242 | → Unchanged (still elevated) | | **Portal vein** | 6.1 mm | 3.9 mm (US) | ↗ Decreased | | **Platelets** | 403 | 223 | ↘ Normalized | | **Shunt size** | 9.9 mm | 9.9 mm | → No Change | --- ## CURRENT SITUATION (February 2026 - 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