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Understanding the Hepatitis B Risk

8/1/2025, 9:20:25 AMMale25-34

I have no medication history and I received the Hepatitis B vaccination when I was 12 years old. Approximately a year and a half ago, I underwent a Hep B triple test, which yielded the following results: both surface antigen and core antigen were non-reactive, while my surface antibody level was recorded at 37.4 ui/ml. Currently, I am in an open relationship and engage in unprotected sexual activities—ranging from vaginal and anal to oral— with a male partner. Interestingly, he occasionally practices safe sex with others but has unprotected oral encounters. I am concerned about the potential exposure to Hepatitis B through my relationship. In light of my vaccination history, how confident can I be in the protection afforded by the vaccine? Are there any estimates regarding the risk levels associated with vaccine effectiveness, particularly for individuals whose antibody levels exceed the 9.9 threshold for immunity?

Drug AllergiesAnaphylaxisAllergy & Immunology

Answers (1)

Cony

8/1/2025, 9:20:45 AM

OpenHealth AI

It’s understandable to be concerned about your potential exposure to Hepatitis B, especially considering your relationship dynamics. Let’s break down your situation.

Main Points:

  1. Vaccination and Immunity: Your Hepatitis B vaccination in childhood and subsequent antibody level of 37.4 ui/ml indicate that you are sufficiently protected against the virus.
  2. Risk Assessment: While your protection level is strong, certain behaviors (like engaging in unprotected sex) can still pose a risk for hepatitis or other sexually transmitted infections (STIs).
  3. Ongoing Practices: Knowing your exposure risks can help inform safer sexual practices.

Explanation:

The Hepatitis B vaccine is highly effective, typically providing long-lasting immunity. Antibody levels over 10 ui/ml are generally considered sufficient to provide good protection against Hepatitis B infection. A level of 37.4 ui/ml indicates a robust immune response.

It is important to remember that while vaccination protects against Hepatitis B, it does not prevent other sexually transmitted infections. Engaging in unprotected sex can increase your risk for these infections.

Next Steps:

  1. Remain Informed: Continuously educate yourself about Hepatitis B transmission methods, focusing on situations like unprotected sex, sharing needles, etc.
  2. Regular Testing: Consider getting regular testing for Hepatitis B and other STIs, especially with multiple partners or varying practices. This can help identify any potential issues early.
  3. Safe Practices: Encourage your partner(s) to engage in safer sex practices, such as using condoms, particularly with new or non-monogamous partners.
  4. Consider Revaccination: If you're worried about long-term immunity, consult with a healthcare professional about the possibility of revaccination or monitoring antibody levels periodically.

By being proactive and informed, you can help mitigate your risk while maintaining your sexual health. If you have further concerns or notice any symptoms, keep track and consider reaching out for more personalized guidance.

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