Persistent Full Body Rash: A Prolonged Mystery
My mother, aged 60 and of average build (5'9", 150 lbs), along with her healthy lifestyle—no smoking, minimal alcohol, and currently on specific medications and supplements—experienced the onset of a mysterious rash during our trip to Turkey in December 2024. Coming from the USA and having no prior skin problems, this sudden issue has now persisted for several months despite consultations with multiple medical professionals. Below is a summary of her symptoms and treatments attempted thus far. **Symptoms:** - Initially appearing on her ankles, the rash has now spread extensively across her upper and lower arms, chest, neck, ears, back, shins, calves, chin, jawline, face, and abdomen. - The rash is accompanied by severe itching, particularly at night and during the morning hours. It often manifests as a sharp, prickling sensation, which is painful, yet no visible causes are apparent. - Sleep has become severely disrupted due to the discomfort. - Even with regular changes of bed linens, dark specks appear on her sheets, clothing, and sometimes even her skin. Occasionally, these specks are surrounded by faint red markings. The lint trap from the dryer also collects numerous specks. - Notably, while she showers, these black specks can sometimes be seen on the soap and seem to evade capture when attempted. - The rash worsens in warm conditions, such as heat from the weather, sun exposure, and hot showers, particularly noticeable during the evening and night hours. **Treatments Administered:** Since February, she has seen three dermatologists, two general practitioners, and a Travel Medicine Specialist, in addition to visits to two urgent care centers. The following treatments have been tried: - Two separate courses of antibiotics (May 5 and May 20), each spanning two weeks. - A two-week trial of Otezla, which showed no improvement (May 5). - Triamcinolone injections were administered twice (February 20 and May 5) without any positive outcomes. - A combination of Triamcinolone cream and ointment provided temporary relief from itching but lasted no longer than two hours. - Taltz injections in both thighs slightly reduced inflammation over a few days, but did not alleviate the prickly sensation or itching. - Oral Ivermectin proved ineffective. - Several applications of Permethrin cream had a short-term effect, alleviating itching for two days but then the rash returned intensely. - A similar pattern followed with Benzyl benzoate 25%, providing temporary relief before the rash worsened again. - Spinosad cream did not yield any results. - Sulfur lotion offered minimal relief from itching for a day or two but has since become ineffective. - Hydroxyzine HCL was not very effective for controlling itching or aiding sleep. - A temporary prescription for Xanax (five tablets) from urgent care on July 19 provided some relief for sleep over three nights. - A course of Prednisone taken from July 25 to July 28 ultimately exacerbated the rash, causing it to spread and become exceedingly itchy throughout the day. **Additional Context:** Since moving into a new home in November 2024, which previously housed a dog, she currently has no pets. - On July 16, 2025, an inspection for bed bugs and other pests was conducted. The exterminator found nothing after a thorough examination, which included disassembling beds and checking the attic. He treated the entire property for various insects to eliminate any potential issues, yet the rash persists unchanged. - From July 19 to July 21, following treatment, she utilized a flea trap near a night light for three continuous days and nights; however, no pests were detected. **Medications Currently Taken:** Liothyronine and extended-release potassium (twice daily). **Supplements:** Vitamin C, Vitamin D/K, B complex, methyl B12, ferrous sulfate, magnesium glycinate, a probiotic, and krill oil. During our travels throughout Turkey, we visited numerous locations including Istanbul, the Gallipoli Peninsula, Troy, Ephesus, Kusadasi, Pamukkale, Antalya, Konya, and Cappadocia, engaging in various activities along the way. I appreciate any assistance and welcome inquiries for more detailed information, such as blood test results. Her current list of medications and supplements will be provided in the comments section.
Answers (1)
7/31/2025, 7:02:16 PM
OpenHealth AI
I can understand how distressing your mother's prolonged rash and intense itching must be for both of you, especially after trying so many treatments without lasting relief. It's clear that you're seeking a resolution to her discomfort, and I am here to help outline some potential considerations and next steps.
Main Points
- Consider Allergic Reactions or Contact Dermatitis: The sudden onset and extensive nature of the rash, coupled with the itchiness and the described dark specks, may indicate an allergic reaction or contact dermatitis, possibly related to environmental triggers encountered in Turkey or in her new home.
- Investigate Potential Infestations or Environmental Factors: Given the presence of mysterious specks and the former presence of a dog in her home, explore the possibility of other pests or allergens that might not be apparent through standard inspections.
- Skin Care and Symptom Management: Focus on gentle skincare and immediate options for itch relief as further investigations are conducted.
Explanation
The wide distribution of the rash, with symptoms worsening in heat and moisture, might point towards an allergic response to something specific that she either came into contact with during her travels or something new in her environment, like allergens or irritants found in her home. The dark specks are unusual; they could be related to various factors, including fungal elements or something from the environment (like mold or dust particles).
Actionable Next Steps
-
Skin Care Adjustments:
- Use a gentle, fragrance-free cleanser and moisturizer to avoid further irritation on her skin.
- Consider using cold compresses or oatmeal baths to help alleviate itch and inflammation.
-
Detailed Environmental Assessment:
- Even though an exterminator found no pests, consider performing a thorough cleaning and inspecting for mold or dust commonly found in newly acquired homes. Involving a specialist who handles environmental allergens might be worth exploring.
- Look into various environmental allergy tests to check for sensitivities to things like dust mites, molds, or other allergens.
-
Track Symptoms and Environmental Changes:
- Maintain a daily symptom diary, noting times when the rash worsens, any new products used, changes in the environment, and relief measures taken. This could help identify potential triggers.
- Investigate her current medications and supplements for possible interactions or side effects that might contribute to the rash.
-
Explore Alternative Treatment Options:
- Discuss with her medical providers the possibility of trying antihistamines that may help with itching, such as diphenhydramine (Benadryl) at night, or topical anesthetics but be cautious of potential reactions.
- If over-the-counter treatments are ineffective, further consider a reassessment of her medications, specifically focusing on switching away from those that track systemic side effects.
-
Specialist Referrals:
- Request a referral to a dermatologist specializing in chronic skin conditions or allergists experienced in polymorphic light eruption or other dermatological conditions that can present like this.
I encourage you to maintain close communication with healthcare providers, as persistent rashes can require a tailored approach to identify and address the underlying cause effectively. Continue to be vigilant, and please feel free to share updates or any additional questions you have as your mother navigates this condition.
Related Questions
Chronic Joint Pain Since Childhood
Since I was eight years old, I’ve endured intense and persistent pain in my joints. Initially, the discomfort was primarily in my knees, characterized by a sharp sensation right beneath the kneecap. As someone on the autism spectrum, I often visualize a strange, soothing thought: the idea of removing my kneecap and using an ice cream scoop to relieve the pressure underneath it. My parents sought help from several medical professionals, all of whom attributed my symptoms to growing pains. I even underwent cancer screenings at the age of nine because doctors felt my level of discomfort was excessive for mere growing pains. At school, I frequently had to wear dual knee braces. When I turned 14, I had a CT scan, but the results were inconclusive; doctors continued to insist it was just growing pains. At 18, I had an X-ray that also revealed nothing abnormal. Now at 20, my joint pain persists and is progressively worsening. My hands now ache in addition to my knees, and on particularly bad days, the pain radiates down to my ankles, making walking and sleeping almost impossible for half the week. The discomfort has entirely hindered my ability to work. My family and I strongly suspect that I may have some form of arthritis, but I struggle to convince the medical community of this due to my young age. My father, who suffers from arthritis himself, often empathizes when I express my pain, telling me, "that sounds familiar." I have broken down in front of numerous doctors, pleading for assistance, yet I consistently leave without answers, only to be scheduled for more scans that come back normal. The medical care I have received thus far has been far from satisfactory; for instance, I was prescribed eye drops that nearly resulted in serious damage to my vision when I consulted an eye specialist. This is just one of many frustrating experiences I’ve faced. I feel completely overwhelmed and in agony, and I have no way to reach out for specialized medical help since my only means of transportation is my father, who is also afflicted by arthritis. I feel lost and in deep pain without a clear path forward.
Seeking Guidance on Persistent Chest Discomfort After Extensive Testing
I'm a 43-year-old male, standing at 5'11" and weighing 180 pounds. My journey began around March to April of 2025 when, despite regularly hitting the gym four times a week, I was struck by severe chest pain along with frequent belching and a tight feeling in my diaphragm. At times, the pain became so intense that I feared it might be a heart attack. **Medical History:** In May 2019, I received a diagnosis of **PVS** and have since been under the care of a cardiac electrophysiologist. Upon experiencing these new symptoms, I consulted my EP, who conducted an EKG right then and set me up with a 7-day heart monitor. The results showed no irregularities. Subsequently, I was directed to a cardiologist, who carried out both a **stress test** and an **echocardiogram**, both of which yielded normal findings. Afterward, I returned to my primary care physician, who speculated that my gallbladder might be involved. An **ultrasound** was performed but revealed no issues. I then requested a **chest X-ray**, which also came back normal. My PCP then considered the possibility of a **hiatal hernia** and referred me to a gastroenterologist; unfortunately, that appointment took almost **five months** to materialize. In the meantime, my symptoms persisted, prompting me to cease weightlifting and switch my focus to **cardio and running**. Surprisingly, these activities didn’t exacerbate my symptoms, though the chest pain remained constant. When I finally saw the gastroenterologist, they suggested an **upper endoscopy**, which took another roughly three months to arrange. During this procedure, I was diagnosed with **Eosinophilic Esophagitis (EOE)**, a condition I had not previously experienced. The doctors also placed a pH monitoring device for acid reflux assessment, which indicated **no unusual acid exposure**. Following this, I began a treatment plan that included a swallowed steroid inhaler and an increased dosage of **omeprazole**. Sixty days later, I underwent another endoscopy, which showed that the EOE had largely resolved, with minimal residual symptoms. Unfortunately, my chest discomfort persisted without any improvement. It has now been about **a year** since these issues emerged, and I still have not found substantial relief. A recent chest MRI completed at a dedicated imaging center revealed no abnormalities. I entertained the idea of **costochondritis**, but again, the MRI did not support that hypothesis. The only minor relief I find comes from consciously pulling my shoulders back and expanding my chest. I continue to experience discomfort around my **diaphragm** and tenderness in the area of the **xiphoid process**. My PCP prescribed a steroid pack, which was somewhat beneficial for the pain but failed to alleviate the pressure or constant discomfort. At this juncture, I feel quite lost and uncertain about my next steps. I would greatly appreciate any insights or experiences from others who have faced similar issues. Additionally, if there are any physicians here willing to offer advice, I am open to traveling to find the answers or relief I'm desperately seeking.
Understanding the Reality of End-Stage Pancreatic Cancer
Navigating the complexities of end-stage pancreatic cancer can be overwhelming, and I'm seeking clarity on what lies ahead. My mother, who is 59 years old and weighs about 115 pounds, received her diagnosis of terminal pancreatic cancer in October 2025. Unfortunately, she has largely rejected the option of chemotherapy and is consuming her pain relief medications—specifically oxycodone and morphine—at an alarming rate. While I’m not worried about the dosage, the severity of her pain has reached a level that is becoming unbearable. Despite this, she is adamant about avoiding any hospital treatment, even though that's where she would receive the most effective pain management. I’ve attempted multiple times to get her medical attention, calling both hospitals and emergency services. However, due to her refusal for assistance, they have also turned us down. It was explained to me that taking her against her will could be considered kidnapping. After consulting with various healthcare professionals, I have been informed that her time may be measured in days or weeks. There’s also a chance that she could slip into unconsciousness, leaving me deeply unsettled. I am already in a state of mourning, yet I am desperate to understand what to expect in the coming days. It is crucial for me to prepare myself—emotionally and mentally—so that I can help ensure her comfort in these final moments. Plans are underway to engage hospice care, but the uncertainty fills me with apprehension. This is my mother, and I want to alleviate my fear so I can provide her with the support she needs as she nears the end of her journey. I yearn to be present for her without being entirely consumed by grief before she passes away. Any guidance or insight you could provide would be invaluable. I'm at a loss for what steps to take next and truly desire to navigate this situation with as much grace and readiness as possible.
Concerns After Gallbladder Surgery (Three Weeks Post-Op) - Is It an Infection?
Profile: - Age: 35 - Gender: Female - Height: 5 feet 4 inches - Weight: 160 pounds - Ethnicity: Asian Duration of Symptoms: Last Three Weeks Location: United States Recent Medical History: Nearly three weeks have passed since my gallbladder removal surgery. Over the last few days, I've noticed a small amount of unclear fluid coming from the incision. I just observed what seems to be pus oozing from the surgical site. Although there is slight tenderness when I move or touch the area, it isn't painful. Thankfully, I haven’t experienced any fever or chills, and there’s no unpleasant odor emanating from the wound. Should I continue to clean it with soap and water, or is it necessary for me to visit the emergency room for further evaluation?
Navigating Ear Infections While Traveling in Thailand
**Age:** 23 **Height:** 6'3" **Weight:** 88 kg **Medication Taken:** 1000mg Bactoclav - Amoxicillin with Potassium Clavulanate, along with pain relief and antihistamines. **Summary:** I’m hesitant to consult a doctor overseas only to receive a prescription for the same antibiotics available at a local pharmacy for a fraction of the price. What strategies can I employ to effectively manage this persistent ear infection? Am I being too hasty in my expectations? I have a long history of ear infections, often triggered by exposure to water or any activity impacting my ears. I regularly use a specialized oil before showering to prevent water from entering my ears. While backpacking in Thailand, I've developed a particularly severe ear infection over the last several days. Initially, a course of 500mg amoxicillin seemed effective, but significantly, just yesterday my condition took a downturn, shifting from nearly healed to painfully inflamed. Now, my ear is not only swollen but also incredibly sore. In an attempt to combat this, I’ve been taking 1000mg Bactoclav - Amoxicillin and Potassium Clavulanate, having consumed seven tablets in the last two days; unfortunately, there's been no noticeable improvement. I’m reluctant to seek medical attention, fearing I would be prescribed the same medication I could acquire from a pharmacy, albeit at a much higher cost. Yet, I’m also starting to question the efficacy of the pharmacy’s medication. I’ve only recently begun the stronger treatment since my symptoms returned. Any advice would be greatly valued! In addition, I’d like to share that just a week into my four-month journey, I feel as though my ongoing ear issues are gradually dominating my life. I am incredibly grateful for this travel opportunity, and while my health isn’t at risk in a serious way, these ear complications are becoming quite overwhelming. Could there be surgical options available? Might there be an underlying health concern that I’m unaware of? It doesn’t seem normal to be plagued by constant ringing, popping sounds, and wax buildup in my ears. Moreover, it feels excessive to have to apply products in my ears every time I shower.