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Could This Be IBS, or Something Different?

7/31/2025, 1:20:25 PMMale25-34

A 33-year-old female, who doesn’t smoke and has a history of a hiatal hernia and asthma, is experiencing ongoing health issues since May 2022. I'm inquiring on behalf of my partner, who has been struggling with these symptoms for quite some time. After undergoing a colonoscopy in July 2022, the results were normal. Despite several visits to the doctor and being given a variety of recommendations, none have proven effective. Notably, her symptoms do not appear to be associated with either dietary choices or stress. The episodes last anywhere from one to two weeks, during which she may need to use the restroom up to fifteen times daily. There are instances of bright red blood, typically occurring after several days of frequent bowel activity. These flare-ups are often accompanied by fatigue, an overall sense of malaise, and occasionally nausea, particularly when the pain intensifies. Although the medical professionals have suggested IBS as a probable diagnosis, her condition frequently disrupts her sleep. Based on my research, IBS is not typically linked with the presence of blood. Any insights would be appreciated. Furthermore, during the initial flare-up in 2022, her calprotectin level measured over 800. A subsequent test last year indicated a significant decrease, now around 70.

AsthmaArthritisCrohn's Disease

Answers (1)

Cony

7/31/2025, 1:20:43 PM

OpenHealth AI

Your partner's symptoms indicate a complex situation, especially with the history of ongoing digestive issues, high calprotectin levels, and the presence of blood in the stool. It's good that she has seen doctors and undergone necessary tests, as this is vital for effective management.

Main Points:

  1. Consider the Potential for Inflammatory Bowel Disease (IBD): The high calprotectin level suggests inflammation in the intestines, which might indicate conditions like Crohn's disease or ulcerative colitis rather than IBS.
  2. Monitor Symptoms Closely: It's essential to keep track of symptom patterns, especially concerning bowel habits and any associated symptoms like fatigue or nausea.
  3. Evaluate Current Management: Given that past treatments have been ineffective, a review might be necessary to reassess her management plan.

Explanation:

Irritable Bowel Syndrome (IBS) typically doesn’t cause blood in stools; the presence of blood alongside such frequent bowel movements raises concerns about other gastrointestinal conditions, such as IBD. Your partner’s high calprotectin levels suggest significant inflammation, which could warrant further investigation.

Next Steps:

  1. Symptom Diary: Encourage her to maintain a detailed diary of her symptoms, noting everything from bowel habits to fatigue levels, and any foods consumed. This may help identify patterns or triggers.
  2. Follow-up Testing: Request further evaluation with her healthcare provider, focusing on a review of her calprotectin levels and possibly additional imaging (like an MRI or endoscopy) to evaluate for possible bowel conditions.
  3. Hydration and Nutrition: Ensure she stays well-hydrated, especially considering the frequent bowel movements. A nutritionist may provide helpful guidance on maintaining a balanced diet.
  4. Symptom Management: Explore over-the-counter options for managing symptoms, such as anti-diarrheal medications, but consult with her doctor before introducing new treatments.

By closely monitoring her symptoms and ensuring a thorough investigation into her condition, your partner can work towards better management and relief from her distressing symptoms. Let me know if you need more insights or specific advice!

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