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Worsening Rash Under My Arm: Seeking Advice

7/30/2025, 4:50:28 PMMale25-34

I'm posting anonymously due to the personal nature of this issue. I'm a 21-year-old female, standing at 5’4 and weighing 115 lbs. This past weekend, I initially thought I had sustained a bug bite while I was busy working on my project car at my fiancé's father’s residence, which is located close to a lake swarming with mosquitoes and has serious flea and ant problems. However, that initial “bite” has now developed into something far more concerning. Recently, what I suspected to be a simple rash transformed as the papules turned into blisters, which are spreading across my armpit. I became anxious thinking about a possible serotonin rash since I take Zoloft and Depakene, and I unfortunately missed doses for two consecutive days over the weekend. Now, I'm increasingly worried about the possibility of shingles or another condition. Two years ago, I experienced an outbreak of HSV, but I have never had chickenpox. Additionally, I have a history of dyshidrotic eczema affecting my hands. I'm quite overwhelmed with this situation and would greatly appreciate any guidance or insights you might have.

ArthritisLupusInternal Medicine

Answers (1)

Cony

7/30/2025, 4:50:45 PM

OpenHealth AI

It sounds like you're dealing with a concerning rash that has evolved from a simple bite to blistering lesions under your arm. Given your history and the recent changes, it's understandable to feel overwhelmed, but let's address your main concerns and provide some clarity.

Main Points:

  1. The rash could result from an allergic reaction, infection, or dermatitis, especially given your history with dyshidrotic eczema.
  2. Your missed doses of medications might contribute to anxiety but are unlikely the direct cause of the rash.
  3. Monitoring the rash and managing symptoms are the best immediate steps you can take.

Explanation:

Rashes can develop for a variety of reasons, such as an allergic reaction to insect bites (like from mosquitoes or fleas), contact dermatitis from something you've touched, or even an infection. The development into blisters increases the likelihood of infection or dermatitis rather than conditions like shingles or a serotonin rash.

While it’s good to be aware of your history with HSV, a herpes outbreak typically looks different and is usually painful and localized. Since you have not had chickenpox, shingles is unlikely, but still worth discussing with a healthcare provider if symptoms worsen.

Next Steps:

  1. Monitor the Rash: Keep an eye on the rash's appearance. If it becomes increasingly red, swollen, or drains fluid, that may indicate an infection.

  2. Avoid Irritants: Keep the affected area clean and dry. Avoid any perfumes, deodorants, or products that might irritate your skin further.

  3. Consider a Cold Compress: To help with itching or discomfort, you can apply a clean, cool cloth to the area for short periods.

  4. Over-the-Counter (OTC) Treatments: Consider using an OTC hydrocortisone cream or antihistamine if you're experiencing significant itching.

  5. Hydrate and Rest: Since you've missed doses of your medications, make sure to resume your prescribed regimen and maintain good hydration. This can help alleviate anxiety and keep your skin healthy.

If the rash does not improve significantly in a few days, continues to worsen, or if you develop other symptoms (like fever), seek further evaluation for potentially more effective treatment. Your ongoing concern is valid, so don’t hesitate to reach out for additional assistance.

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