Understanding Selective IgA Deficiency: What’s Next?
Hello everyone! I recently underwent several blood tests, and I was surprised to receive the following information in the results: "Coded entry - Immunoglobulin A level (XE25B) < 0.1 g/L [0.7 - 4] - Below low reference limit. Test result - TTG ABS (IGG) Report, Normal, No Further Action Required." While I have had numerous blood tests in the past, I don’t recall experiencing a test for this specific marker before. To give you a bit of context, I have hypothyroidism, a history of recurring ear infections, and I tend to catch colds frequently (though that has improved since I began working from home a few years ago). Additionally, there have been times in the past where I've received 'false positive' results suggesting chronic infections, but follow-up tests have always reassured me that there were no underlying issues. I’m not seeking an online diagnosis, but I am genuinely intrigued about what steps might be necessary moving forward. Should I expect my doctor to contact me regarding this finding? I’ve come across information indicating that individuals with this condition may need to keep a card on hand for potential blood transfusions. I reside in the UK, which may influence how this is handled. Typically, we don’t engage directly with immunologists unless there is a serious and ongoing problem; all assessments are conducted through a general practitioner. For instance, it wasn't until I was tested for another issue that I discovered my hypothyroidism was a result of thyroiditis after several years of being unaware. Any insights or guidance would be appreciated!
Answers (1)
7/30/2025, 1:40:50 PM
OpenHealth AI
Main Points: You have a low level of Immunoglobulin A (IgA) indicating selective IgA deficiency, which may require some attention. Your history of infections and current health conditions are relevant. It’s possible your doctor will contact you; understanding what this means for your health is key.
Explanation: Selective IgA deficiency means your body has low levels of immunoglobulin A, an antibody important for mucosal immunity (in areas like the respiratory and digestive tracts). This can lead to an increased risk of infections, especially respiratory ones, and sometimes gastrointestinal issues as well. Many people with this condition remain relatively healthy, but it's wise to be aware of your situation.
Given your history of recurring ear infections and colds, it's understandable to have concerns about how this deficiency might affect you. It’s good that other blood tests like TTG (Tissue Transglutaminase Antibodies) were normal, as this suggests no immediate concern for other serious conditions like celiac disease.
Next Steps:
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Await Contact from Your Doctor: Since IgA deficiency can mean more frequent infections, your healthcare provider may reach out to discuss this finding and any necessary follow-up tests or assessments. If you don't hear from them in a reasonable timeframe, consider contacting your GP for clarification.
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Keep a Health Journal: Note down any infections, frequency, and types of illnesses you experience. This information can be helpful for your doctor to understand the impact of your IgA deficiency and to tailor any advice or treatments.
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Be Aware About Emergencies: You rightly mentioned carrying information about your IgA deficiency, especially in medical situations like blood transfusions. Speak to your doctor about obtaining a medical alert card that states your condition; this can be crucial in emergencies.
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Assess Your Lifestyle: Continue to monitor your health, focusing on a balanced diet, adequate hydration, and good hygiene practices. Regular handwashing and avoiding close contact with sick individuals can help reduce your risk of infections.
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Consider Lifestyle Modifications: As you mentioned improvements since working from home, maintaining a less stressful environment and good sleep hygiene can also improve your immune health.
Feel free to reach out with more questions if any concerns arise as you process this information, and take care!
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