Persistent Mouth Irritation Following Impetigo
Subject: Female, aged 27, originally from the UK and currently residing in Canada. The issue began upon my return to Canada. Current Medications: Lithium, Gabapentin, Birth Control (NuvaRing). I really need some assistance here. This saga initiated with a tiny patch of eczema on my chin that persisted for nine months. It would flare up occasionally but wasn't particularly bothersome. After experiencing a stressful period due to relocating, I noticed the redness spreading from my chin to the area just above my lip, although it remained manageable at that point. Then, I mistakenly consumed some acidic fruit, which led to angular cheilitis, and subsequently, this developed into impetigo around my mouth and left eye. Thankfully, antibiotics were effective for that. However, I’m now stuck with a persistent, itchy redness and discoloration surrounding my mouth, which feels tight, and my lips seem swollen. The angular cheilitis keeps reoccurring; if I fail to moisturize my lips every hour, they end up cracking. I've been trying numerous recommended moisturizers, but I have strong negative reactions to petroleum and paraffin products, so I avoid those. Thus far, I've utilized CeraVe Hydrating Serum, 1% hydrocortisone cream (which provides some relief), lidocaine at night to alleviate itching (it helps a little), Aquaphor lip balm, Good Molecules lightweight moisturizer, antihistamine gel, antibiotic ointment prescribed for the impetigo, and over-the-counter oral antihistamines. Despite these efforts, nothing seems to resolve the issue. What could this be, and what steps should I take next?
Answers (1)

7/29/2025, 11:50:48 PM
OpenHealth AI
It sounds like you’re dealing with a complex situation involving persistent mouth irritation that has evolved through various stages, including eczema, angular cheilitis, and impetigo. The redness, tightness, and swelling you are experiencing can be quite uncomfortable, and it's essential to address it effectively.
Summary of Key Points:
- The irritation may be related to skin conditions that can be exacerbated by factors like stress, allergies, or irritants.
- Persistent moisturizing and avoiding known irritants is crucial.
- Consider evaluating for potential underlying causes and alternative treatment options.
Explanation:
Your description suggests a progression of skin issues that has led to ongoing symptoms around your mouth. Given your history of eczema and angular cheilitis, it seems like it could be a combination of both contact dermatitis and some form of chronic irritation or allergic reaction, particularly since your symptoms worsen without frequent moisturizing. Your avoidance of certain products due to negative reactions further complicates treatment.
Prioritized Next Steps:
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Moisturizing Routine:
- Continued Frequent Moisturizing: Focus on applying a suitable moisturizer every hour. You can try using natural oils like coconut oil or shea butter, which tend to be less irritating and provide good hydration without petroleum-based ingredients.
- Barrier Creams: Look into barrier creams specifically designed for sensitive skin, which can protect and prevent moisture loss.
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Gentle Skincare Products:
- Hypoallergenic Moisturizers: Continue using hypoallergenic products and consider trying others like La Roche-Posay Cicaplast or Eucerin for sensitive skin. Avoid any fragrances and parabens.
- Avoid Irritants: Steer clear of any known irritants, including acidic foods, until your skin is healed.
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Topical Treatments:
- Hydrocortisone Use: Continue using 1% hydrocortisone cream short term for flare-ups. Do not use it for prolonged periods to avoid skin thinning.
- Consider Non-steroidal Options: Over-the-counter creams, such as calamine lotion or aloe vera gel, may provide soothing relief.
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Monitoring Symptoms:
- Keep a diary of what seems to trigger flare-ups to identify potential allergens or irritants, including foods or environmental factors. This will help recognize patterns in your symptoms and aid in management.
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Dietary Considerations:
- Maintain a balanced diet rich in vitamins, especially B vitamins, which can help with skin health, and stay hydrated.
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Stress Management:
- Since you mentioned stress as a triggering factor, consider incorporating stress-relieving activities into your routine, like yoga, meditation, or gentle exercise.
If symptoms persist despite these measures, consider evaluating with a dermatologist for further assessment or to explore other underlying causes, such as allergies or other dermatological conditions. Let me know if you have further questions or need more detailed advice!
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