Concerns About Elevated Creatinine Levels
Greetings, I am a 26-year-old woman diagnosed with bipolar disorder. Approximately two years ago, I was prescribed lithium. During a recent evaluation in October, my creatinine level was recorded at 116, and I also exhibited a low glomerular filtration rate (GFR). Subsequently, I underwent an ultrasound and a urine analysis, both of which returned normal results. After consulting with an internal medicine physician, she suggested that dehydration might be the cause, even though I consume between 1.5 to 2 liters of water daily. Should I be worried about my situation?
Answers (1)

7/29/2025, 11:20:46 PM
OpenHealth AI
It's understandable to feel concerned about elevated creatinine levels, especially when you have a history of lithium use. Your recent tests, including the normal ultrasound and urine analysis, are reassuring indicators. Elevated creatinine and low GFR can have several causes, and while dehydration is one possibility, there may be other factors at play.
Explanation:
Creatinine is a waste product from muscle metabolism, and healthy kidneys filter it out of the blood. When levels are elevated, it can indicate that the kidneys aren’t functioning optimally. Although you are ensuring adequate hydration, factors like medications (such as lithium), muscle mass, and even certain diets can influence creatinine levels.
Moreover, lithium can sometimes impact kidney function, so monitoring is key. Given that your tests have shown normal kidney structure and function otherwise, this is a positive sign. However, your health should still be proactively managed.
Next Steps:
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Monitor Symptoms: Keep a close eye on any changes in your health, such as fatigue, swelling in your legs or ankles, changes in urine output, or any new symptoms.
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Hydration: Continue to drink 1.5 to 2 liters of water daily, especially if you're physically active or in hot weather. You can also incorporate hydrating foods (like fruits and vegetables) into your diet.
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Dietary Review: Ensure your diet is balanced. Reducing salt intake and moderating protein can positively affect kidney function. Consider speaking with a dietitian if you have specific dietary concerns.
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Regular Check-ups: Schedule regular follow-ups with your healthcare provider to monitor your kidney function. They may recommend further tests or adjustments to your lithium dosage as necessary.
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Discuss with Doctor: When you meet with your healthcare provider next, express your concerns and ask about the possibility of checking for other conditions that might affect kidney function, especially if there are any changes in your symptoms or medication regimen.
Remember, staying informed and involved in your health is essential, and your healthcare team is there to support you! If you have any more questions or need clarification, feel free to ask.
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