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Dealing with MRSA and Central Line Complications: Seeking Advice

7/29/2025, 10:20:31 AMMale25-34

Age: 23, Weight: 150 lbs. I am currently taking Clindamycin along with several other medications daily. My medical history includes Ehlers-Danlos syndrome, gastroparesis, intestinal dysmotility, dysautonomia, urinary retention, mast cell dysfunction, and avascular necrosis. I have a tunneled central line, a GJ tube for nutrition, rely on catheters due to urinary issues, and have also undergone ileostomy surgery. Additionally, I am on total parenteral nutrition (TPN) and have experienced sepsis and septic shock in the past. Hello everyone, over the last few weeks, I've been noticing pus at the site of my central line. After consulting with my physician, I underwent both blood and wound cultures. My doctor prescribed oral Clindamycin via my jejunostomy (j-tube). Fortunately, my blood culture results came back negative. However, I received a call today informing me that my wound culture tested positive for MRSA. I also saw my infusion nurse today for a dressing change, which was quite painful, and I’m still experiencing significant pus discharge. My physician has advised me to begin IV antibiotics to prevent the infection from entering my bloodstream, leaving the decision up to me. Given my extensive history of blood infections - the latest occurring in April - I realize the severity of having a resistant strain in my system. My experiences with sepsis have left lasting trauma, as I've faced it more times than I can recall. Therefore, I am inclined to opt for the IV antibiotic treatment; however, I have anaphylactic reactions to nearly all options available, which is a direct result of my mast cell condition. Every antibiotic I’ve tried has led to severe throat constriction, resulting in intubation on three separate occasions. Such reactions require that I have premedication and monitoring, necessitating a hospital admission for treatment. I am receiving this information on a Monday night and hope to be admitted the following day for treatment. My concern, however, is multifaceted: I have a job interview scheduled for Wednesday evening, and my rent is due soon. Losing my apartment is a real fear if I do not secure this new job soon. In the past, I've nearly faced eviction due to hospitalizations, and my previous employment was terminated because they could not accommodate an extended medical leave after my AVN surgery, despite having proper documentation from my surgeon. How serious is the risk of postponing admission for three days? While I likely will seek treatment sooner due to the infection's location causing me significant anxiety, I wish to weigh all my options. If it’s generally deemed safe to wait, I would prefer to attend the job interview and ensure my housing situation remains stable.

Drug AllergiesAnaphylaxisAllergy & Immunology

Answers (1)

Cony

7/29/2025, 10:20:55 AM

OpenHealth AI

Given your situation, it is understandable to feel anxious about the infection and the potential implications for your job interview and housing stability. Here's a structured response addressing your concerns:

Main Points

  1. MRSA and Infections: MRSA (Methicillin-resistant Staphylococcus aureus) can lead to serious complications, particularly with your history of infections and central lines.
  2. Risks of Delaying Treatment: Postponing treatment for three days can increase the risk of the infection spreading, which is concerning given your medical history and the anxiety you're experiencing.
  3. Balancing Health and Responsibilities: It's challenging to manage health crises alongside personal and professional commitments.

Explanation

MRSA infections can be serious, especially in individuals with weakened immune systems or those with central lines, as the bacteria may enter the bloodstream and cause fevers, chills, and a significant risk of sepsis. Given your history, including previous episodes of sepsis, it’s critical to take the wound culture result seriously.

Waiting three days for IV antibiotics carries risks. Infections can escalate quickly; therefore, it's important to monitor symptoms like increased redness, swelling, fever, or worsened pain at the central line site. You should prioritarily ensure your health and well-being.

Next Steps

  1. Consider Immediate Hospital Admission: Given your anxiety about the infection and past experiences with sepsis, it’s advisable to accept the IV antibiotic treatment as soon as possible. This will help prevent potential complications.

  2. Discuss Options for Job Interview: Communicate openly with your potential employer about your situation if you feel comfortable. Many employers are understanding, especially if you explain the importance of the job yet the need for immediate health care. If necessary, you can ask if the interview can be rescheduled.

  3. Seek Support for Housing Concerns: Consider talking to a friend or family member for support during this time or explore local resources available for individuals facing difficulties with housing due to medical situations.

  4. Manage Infection Symptoms: Until you start IV antibiotics, keep the area clean and covered. Avoid manipulating or touching the central line site, and monitor for any change. If symptoms worsen, seek immediate care.

  5. Document all communications: Keep records related to your health and job for your records, which may help demonstrate your situation if any issues arise with your landlord or employer.

Your health is paramount, and addressing this infection promptly is crucial. While it's important to consider the job interview, your well-being should take precedence, as staying healthy will ultimately allow you to pursue your career aspirations in the long run. Take care of yourself, and ensure you communicate effectively with your healthcare team about your options and any concerns related to your allergies to antibiotics.

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