Understanding Adenosine's Impact on WPW Diagnosis
Hello everyone! A few years ago, I underwent assessment for Wolff-Parkinson-White (WPW) syndrome when an electrophysiologist noticed something unusual on my ECG during a preoperative cardiac evaluation. Despite experiencing various heart-related symptoms over the years, nothing definitive was discovered. Unfortunately, I can’t recall the specific findings from the ECG that prompted my referral for an electrophysiology study. However, upon my arrival for the EP study, the doctors decided to administer adenosine instead, mentioning that there was only a 20% probability of having WPW if my heart were to stop, making the EP study unnecessary. Upon receiving adenosine, my heart indeed stopped, and I was discharged shortly thereafter. Since then, I've consulted with a cardiologist who believes this incident effectively rules out WPW, but my searches online suggest it doesn’t definitively exclude anything. I’m seeking clarity on what it entails when adenosine halts my heart while in a normal rhythm and whether I should persist in discussing my concerns with healthcare providers. Oddly, my heart rate tends to spike unexpectedly, and I eliminated caffeine from my diet last year. For instance, just earlier tonight, I felt a "wooshing" sensation in my chest, and my heart rate jumped from around 60 to 120 beats per minute while at rest, lasting a mere few minutes. I frequently notice my heart rate reaching the 120s to 140s with minimal exertion. For context, I'm a 32-year-old female, standing 5'1" and weighing 170 lbs. Throughout the past year, I've undergone various tests, including a stress echo, echocardiogram, and a Holter monitor, all of which produced a negative tilt table test. The Holter monitor recorded my heart rate fluctuating between the 40s and 140s without any physical activity. Additionally, I've woken up with my heart rate recorded in the 140s, remaining elevated above 100 beats per minute for about 10 to 15 minutes. A Kardia 1 lead monitor indicated sinus tachycardia, which was subsequently confirmed by a physician.
Answers (1)

7/28/2025, 6:10:52 AM
OpenHealth AI
It sounds like you have been managing complex heart-related symptoms for some time, and your concerns are understandably significant given your experiences. Here's a clearer understanding of your situation and some actionable steps to consider:
Summary of Key Points:
- The administration of adenosine during your electrophysiology study was meant to reveal potential heart conduction issues.
- The stopping of your heart while receiving adenosine in a normal rhythm does not definitively rule out conditions like WPW but suggests that there may not be an active reentrant circuit associated with it.
- The symptoms of increased heart rate and palpitations you experience could be related to other factors, and it’s important to continue discussing your symptoms with healthcare providers.
Explanation:
Adenosine is a medication often used in a controlled setting to temporarily stop the heart to reset its rhythm and diagnose issues related to heart rhythms. The fact that your heart stopped temporarily suggests the heart's conduction system is functioning but may not be indicative of WPW specifically. Generally, if WPW was present, the administration of adenosine might have caused a change in heart rhythm or an arrhythmia, potentially showing signs of collateral circuits.
Your experience of a rapid heart rate (tachycardia) and "wooshing" sensations could be linked to various factors such as anxiety, autonomic dysregulation, or other forms of normal sinus tachycardia rather than WPW directly.
Actionable Next Steps:
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Keep a Symptom Diary: Record your heart rate changes, symptoms (like the "wooshing" sensation), and any potential triggers (activity level, stress, etc.). This can help your healthcare provider identify patterns.
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Follow Up with a Cardiologist: Given your ongoing symptoms and fluctuations in heart rate, continue discussing these issues with a cardiologist. Ask specifically about your tachycardia and any concerns regarding your previous tests, especially in light of your adenosine experience.
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Consider Autonomic Function Testing: If your symptoms persist or worsen, discuss the potential for additional testing focused on how your autonomic nervous system regulates your heart rate.
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Lifestyle Adjustments: While you've already eliminated caffeine, consider monitoring other factors that could influence your heart rate, such as hydration, sodium intake, stress management techniques (like deep breathing or meditation), and regular exercise as tolerated.
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Educate Yourself: Stay informed about your condition by discussing any test results with your doctor, and seek clarity on anything that remains confusing. Being well informed can help you feel more in control of your health.
Your symptoms deserve attention and understanding, and continuing conversations with your healthcare providers is important. If you feel your concerns are not being addressed, seeking a second opinion may be appropriate. Always trust your instincts when it comes to your health.
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