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Can Amlodipine and Metronidazole be Taken Together Safely?

7/27/2025, 3:50:25 PMMale25-34

Recently, I visited my healthcare provider, who recommended that I take 5 mg of amlodipine (Norvasc) daily to manage my blood pressure, along with a 7-day course of metronidazole at 500 mg, prescribed to be taken twice daily for bacterial vaginosis (BV). Upon reviewing the medication container for metronidazole, I noticed a warning that states, "Consult your doctor or pharmacist before taking any additional medications." My doctor, however, did not clarify whether it was appropriate to use these medications concurrently; she simply indicated that I should start taking both. I typically take amlodipine at 4 PM. Given this schedule, I am wondering if it is safe to administer metronidazole in the morning and again later in the evening?

Family MedicineInternal MedicinePreventive Medicine

Answers (1)

Cony

7/27/2025, 3:50:39 PM

OpenHealth AI

You can safely take amlodipine and metronidazole together; however, paying attention to how you schedule the doses is important.

Amlodipine is a medication primarily used to lower blood pressure, while metronidazole is an antibiotic effective against certain infections, like bacterial vaginosis. There are no known significant interactions between these two medications, which generally allows for their concurrent use.

Next Steps:

  1. Timing Your Medications: Since you typically take amlodipine at 4 PM, you can take metronidazole in the morning and again in the evening, well before or after your amlodipine dose. For example, taking metronidazole at 8 AM and 8 PM would work well.

  2. Watch for Side Effects: While it’s generally safe to combine these medications, be aware of how you feel. Common side effects of metronidazole can include nausea, diarrhea, and a metallic taste. If you experience anything unusual or concerning, it's important to monitor those symptoms closely.

  3. Hydration: Ensure you're drinking plenty of fluids, especially while taking metronidazole, to help your body process the antibiotic effectively.

  4. Communication is Key: If you have any lingering concerns about interactions or how to proceed, don’t hesitate to contact your healthcare provider or pharmacist for clarification. They can provide personalized guidance tailored to your health circumstances.

This approach should help you manage both your medications effectively while maintaining your health. If you have any more questions or experience any side effects, feel free to reach out.

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