Concerns Regarding Hepatitis C Test Results
At 34 years of age, standing 5'4" and weighing 250 pounds, I lead a lifestyle that doesn’t include smoking or drug use. On July 22, I underwent testing at my gynecologist's office for various sexually transmitted diseases, including a check for hepatitis C antibodies. The results were all negative. However, on July 24, I sought testing at an urgent care center due to the delay in receiving my results from the gynecologist. This time, I received a positive result for both the hepatitis C antibody and the RNA (NAAT) test, with a high score of 3.29 H. I am not someone with a compromised immune system, and I regularly take biotin supplements daily at a dose of 5000mcg. Importantly, on the day of my first test (July 22), I had not yet taken any biotin, while I had taken my supplement on July 24. To my knowledge, I have not engaged in any blood-to-blood contact with others. I did have unprotected sexual encounters, one occurring roughly 12 weeks ago with an individual who assured me he had been tested and confirmed as negative. More recently, three weeks ago, I was with another person who mentioned his last test was four months prior; he claimed I was his sole partner since then, apart from his ex. Given this situation, I am puzzled as to how I could test negative for antibodies initially and then have a positive result just two days later. Is it conceivable that the positive results for both the antibody and RNA tests could be erroneous? This whole experience has left me feeling extremely anxious.
Answers (1)
7/26/2025, 10:30:51 PM
OpenHealth AI
Key Points: You have received mixed hepatitis C test results, which can understandably cause anxiety. While the initial negative antibody test and subsequent positive tests raise questions, it is essential to understand how hepatitis C testing works and what steps to take next.
Explanation: Hepatitis C testing typically involves two steps: the antibody test and the RNA (viral load) test. The initial antibody test checks for antibodies against the virus, which may not be detectable immediately after exposure (the "window period" can last several weeks). This means that if you were recently infected, you might receive a false negative on the antibody test. However, the RNA test detects the virus itself and can confirm an active infection.
Given that your antibody test was negative on July 22, but you tested positive two days later, it's possible you were in the early stages of infection during the first test. Your lifestyle factors, including no drug use, may lower your risk, but hepatitis C can still be transmitted through unprotected sex, especially with multiple partners.
Next Steps:
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Confirmatory Testing: Schedule a follow-up test with your healthcare provider to confirm the results of the positive tests and discuss further testing for the specific hepatitis C genotype. This is essential for determining the appropriate treatment.
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Monitoring Symptoms: While waiting for follow-up, monitor yourself for any symptoms related to hepatitis C, such as fatigue, jaundice (yellowing of the skin or eyes), or abdominal pain. Document these symptoms.
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Tackle Anxiety: Consider engaging in stress-relief activities such as meditation, yoga, or talking to a counselor to manage your anxiety regarding your test results.
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Communicate with Partners: It may also be advisable to inform your recent sexual partners about your situation so they can consider getting tested, as this can help prevent further transmission.
If your situation feels overwhelming, remember that resources are available for support, both medically and emotionally. You are not alone in this experience.
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