Concerns Regarding Low Platelet Count and MCHC Levels
Hello everyone! I'm a 24-year-old woman who underwent blood testing yesterday, which included TSH with reflex, CBC with differential, iron panel, ferritin, CMP, and vitamin D. The results were mostly normal, but I noticed that my platelet count was low, my mean corpuscular hemoglobin concentration (MCHC) was below normal, and my mean platelet volume (MPV) was elevated. My ferritin and iron levels positioned themselves at the lower boundary of normal. My doctor has advised me to repeat the platelet count in two weeks. However, I find myself grappling with anxiety and anticipating the worst during this waiting period, especially since I often struggle with health anxiety. It's worth noting that I've had a history of iron deficiency. Lately, I've been experiencing frequent bruising, fatigue, feeling unusually cold, and even some hair loss. I'm trying to convince myself that perhaps I might have iron deficiency anemia, yet my iron and ferritin levels turned out to be normal. For those interested, here are my specific lab results: - Ferritin: 10 ng/mL (normal range: 8–252) - Iron: 67 mcg/dL (normal range: 50–170) - Total Iron Binding Capacity (TIBC): 407 mcg/dL (normal range: 250–450) - Iron Saturation: 16% - White Blood Cells (WBC): 5.13 (normal range: 4.00–10.80) - Red Blood Cells (RBC): 4.16 (normal range: 4.10–5.40) - Hemoglobin (HGB): 12.1 (normal range: 12.0–16.0) - Hematocrit (HCT): 38.3% (normal range: 36.0–47.0) - Mean Corpuscular Volume (MCV): 92.1 (normal range: 78–100) - Mean Corpuscular Hemoglobin (MCH): 29.1 (normal range: 27.0–31.0) - MCHC: 31.6 (low; normal range: 33.0–36.0) - Red Cell Distribution Width (RDW): 13.6 (normal range: 11.5–14.5) - Platelets (PLT): 137 (low; normal range: 150–350) - MPV: 12.4 (high; normal range: 7.4–10.4) Additionally, I recently endured a severe bout of strep throat about a month ago, which necessitated two rounds of antibiotics. Aside from the platelet count anomaly, my CMP, TSH, and vitamin D results were all within normal limits. Given this context, should I be concerned about experiencing any serious health issues? Thank you for your insights!
Answers (1)

7/23/2025, 3:31:37 PM
OpenHealth AI
It's understandable to feel anxious about your lab results, especially given the low platelet count and the other symptoms you've mentioned. Let’s break down your situation to provide clarity and actionable next steps.
Summary of Key Points:
- Your low platelet count and slightly low MCHC are noted, but the remaining blood results are mostly normal.
- The symptoms you're experiencing, such as fatigue, bruising, and feeling cold, should be monitored.
- Your history of iron deficiency may contribute to your symptoms, even if your current iron panel appears normal.
Explanation:
Your platelet count of 137, although below the normal range, is only slightly so. A variety of factors can affect platelet levels, including recent infections like strep throat or medications (e.g., antibiotics). Your MCHC being low might indicate a mild concern regarding hemoglobin concentration but isn’t typically alarming by itself.
Frequent bruising can be caused by low platelet counts, and feelings of fatigue and being cold can be related to iron levels or a number of other reasons. It is good that your doctor suggested repeating the tests in two weeks, as this will help establish whether the low platelet count is persistent or not.
Actionable Next Steps:
-
Monitor Symptoms:
- Keep track of your bruising, fatigue, and any new symptoms in a journal. Note any changes in frequency or intensity. This will be helpful for your doctor during your next visit.
-
Diet and Nutrition:
- Focus on consuming iron-rich foods to support your health since your ferritin is at the lower end of normal. Incorporate foods like leafy greens, lean meats, beans, and fortified cereals.
- Pair these with vitamin C-rich foods (like citrus fruits) to enhance iron absorption.
-
Hydration:
- Drink plenty of fluids, especially if you feel fatigued or cold. Dehydration can sometimes contribute to fatigue.
-
Manage Anxiety:
- Practice relaxation techniques such as deep breathing, meditation, or gentle exercises like yoga, which can help reduce anxiety while waiting for your next test.
-
Follow Up with Your Doctor:
- Stick to the plan of repeating the platelet count as advised, and bring up any new symptoms or concerns you may have since your last test.
It’s natural to feel anxious, but try to focus on the manageable aspects of your situation. It's a positive step that your doctor is monitoring your condition, and you’re taking an active role in your health. If symptoms worsen significantly, such as increased bruising or bleeding, please seek further advice. Let me know if you need any more information or support!
Related Questions
Wound Treatment and Recovery
Patient info: 32F (Medication: Amlodipine 2.5mg and Norethindrone) reported a history of high blood pressure and vaping. Two weeks prior, I underwent a double matrixectomy on my big toe, treated with phenol. Following the procedure, I was prescribed cefadroxil for ten days and advised to apply mupirocin to aid the wound healing process. While one side of the toe appears to be recovering effectively, I have concerns regarding the other side's progress. My podiatrist recommended allowing the wound to breathe whenever possible, so I've taken measures to keep it uncovered and avoid contact with surfaces. I place a gauze pad to keep the adjacent toe from touching the left inner part of the affected area, doing this for approximately one to two hours each day. However, I’ve noticed that the inner area, particularly near the nail on the left side, seems to be slightly reopening each time I clean it and soak it in Epsom salt. After cleaning, I let it air dry. Since my podiatrist is unavailable until Monday and this situation does not qualify as an emergency, I'm seeking guidance on whether this is typical for wound healing (this is my first experience with such wounds) and if I should continue the current air-drying practices. Are there any additional recommendations on managing my care, or does it seem like both sides are healing adequately?
Chronic Cough Since 2018
I’m a 60-year-old woman, 5'5" tall, weighing 120 pounds. I have not been on any medication until recently. My doctor prescribed me gabapentin, but after just one dose, I felt extremely inebriated, almost as if I had consumed a significant amount of alcohol. I'm perplexed about why gabapentin was prescribed to me in the first place. I'm feeling quite frustrated and financially pressured as I seek answers to resolve this issue.
Managing a Cut on the Penis: A Guide
As a 15-year-old male, I recently experienced an unfortunate incident while grooming my genital area. While shaving, my razor unexpectedly snagged and pulled on the skin, resulting in a cut on the underside of my penis, leaving a small flap of skin attached. I’ve already cleaned the area to minimize the risk of infection. What steps should I take next to properly care for this injury?
Frequent Vomiting Following Mild Traumatic Brain Injury: A 22-Year-Old's Struggle
A 22-year-old male, measuring 5 feet 11 inches tall and weighing 140 pounds, grapples with a troubling medical issue. His current prescriptions include 75mg of Sertraline and 20mg of Omeprazole in his daily regimen. This saga began three years ago when he endured a severe concussion from a mountain climbing incident, resulting in what is termed as a mild traumatic brain injury (TBI). Post-accident, he endured numerous challenges, but gradually, many dissipated, leaving him with a few persistent symptoms—predominantly migraines, mood fluctuations, and the most distressing one: daily vomiting bouts that occur several times throughout the day. This recurrent vomiting began shortly after his primary recovery phase from the concussion and has since become a consistent part of his life. His episodes usually commence each morning, often starting with bile, due to his stomach being empty. Throughout the day, he experiences additional nauseous moments, which typically result in further vomiting, sometimes linked to meals, but rarely exceeding 2-3 occurrences in a day. Despite this, he often produces small amounts of vomit, typically comprised of previously consumed food. In search of answers, he underwent an upper endoscopy, revealing only mild inflammation, and a gastric emptying study, which returned normal results. He remains puzzled, as there do not appear to be clear food triggers, unless he consumes a large amount or highly unhealthy foods, both of which are uncommon for him. His body gives him little warning; instead of extreme abdominal discomfort, he experiences a sudden urge to gag, often just once or twice before the vomiting ensues. His gastroenterologist suggested that with the normal gastric emptying results, he should return to a neurologist for further evaluation. He previously visited a neurology clinic, but his experience was frustrating; the neurologist dismissed his concerns, attributing them primarily to anxiety, a notion he finds hard to accept. Despite identifying as someone who can be anxious, he does not believe this mental state is the root cause of his vomiting, particularly as it occurs even in calm situations. This ongoing issue is starting to affect his work performance as an EMT while he pursues nursing studies—having to suddenly excuse himself to vomit is both alarming and embarrassing. He utilized a TBI clinic for support, but they have not offered much insight into this specific problem. Although they have provided assistance in other aspects of his recovery, he feels they lack clarity on the vomiting. He has experimented with various techniques aimed at alleviating anxiety, yet they have proven ineffective, given he often experiences these episodes when he is not particularly anxious. As he contemplates potential next steps, he wonders whether finding a different neurologist would be advisable or if there are alternative options available to him. The ongoing nature of his symptoms deeply concerns him, particularly the toll daily vomiting is taking on his body and its impact on weight gain. Since his injury, he has struggled to regain lost weight, as consuming larger meals tends to trigger further vomiting.
Seeking Guidance for Ongoing Illness
Age: 19 For more than eight months, I have been grappling with an illness that has left me in a persistent state of distress. Currently, I am taking ondansetron to manage my nausea, but I was also prescribed lansoprazole. Unfortunately, the latter made it very difficult for me to eat, prompting me to discontinue its use against medical advice. I understand that this choice was not ideal. My situation is complicated further by the news that I might remain on a waiting list for a gastroenterology appointment until March or April of next year, hit hard by this condition since December. Initially, my episodes of vomiting occurred about once a week or every other week. However, things escalated to a point where I often experienced nausea for several days, followed by multiple days of vomiting. After that, I would have short intervals where I could eat, but eventually, the cycle would start anew, repeating every few days. Lately, my throat has also been quite sensitive. For instance, over the past two days, I’ve found it impossible to drink anything cold. Today, I felt nauseous even after laughing. Just a week ago, I had difficulty coughing without ending up sick, and I can't even take large gulps of liquids without discomfort. I have undergone several tests, including an endoscopy, MRI, and blood tests, all of which returned normal results. If you need details about specific blood tests to better understand my situation, feel free to ask. I'm reaching out for any advice you might have because I don’t know how much longer I can cope with this. Eating has become a significant struggle, and I avoid social gatherings where alcohol is served as I can’t tolerate it anymore, which is a drastic change since I never used to have issues in that regard. Moreover, I find myself anxious about going out due to fears of an uncertain place to manage my symptoms. Any recommendations or guidance on how to obtain medical assistance more swiftly or insights into what might be at play here would be greatly appreciated. I’ve searched online for answers, but haven’t had much luck.