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Concerns Regarding Low Platelet Count and MCHC Levels

7/23/2025, 3:30:58 PMMale25-34

Hello everyone! I'm a 24-year-old woman who underwent blood testing yesterday, which included TSH with reflex, CBC with differential, iron panel, ferritin, CMP, and vitamin D. The results were mostly normal, but I noticed that my platelet count was low, my mean corpuscular hemoglobin concentration (MCHC) was below normal, and my mean platelet volume (MPV) was elevated. My ferritin and iron levels positioned themselves at the lower boundary of normal. My doctor has advised me to repeat the platelet count in two weeks. However, I find myself grappling with anxiety and anticipating the worst during this waiting period, especially since I often struggle with health anxiety. It's worth noting that I've had a history of iron deficiency. Lately, I've been experiencing frequent bruising, fatigue, feeling unusually cold, and even some hair loss. I'm trying to convince myself that perhaps I might have iron deficiency anemia, yet my iron and ferritin levels turned out to be normal. For those interested, here are my specific lab results: - Ferritin: 10 ng/mL (normal range: 8–252) - Iron: 67 mcg/dL (normal range: 50–170) - Total Iron Binding Capacity (TIBC): 407 mcg/dL (normal range: 250–450) - Iron Saturation: 16% - White Blood Cells (WBC): 5.13 (normal range: 4.00–10.80) - Red Blood Cells (RBC): 4.16 (normal range: 4.10–5.40) - Hemoglobin (HGB): 12.1 (normal range: 12.0–16.0) - Hematocrit (HCT): 38.3% (normal range: 36.0–47.0) - Mean Corpuscular Volume (MCV): 92.1 (normal range: 78–100) - Mean Corpuscular Hemoglobin (MCH): 29.1 (normal range: 27.0–31.0) - MCHC: 31.6 (low; normal range: 33.0–36.0) - Red Cell Distribution Width (RDW): 13.6 (normal range: 11.5–14.5) - Platelets (PLT): 137 (low; normal range: 150–350) - MPV: 12.4 (high; normal range: 7.4–10.4) Additionally, I recently endured a severe bout of strep throat about a month ago, which necessitated two rounds of antibiotics. Aside from the platelet count anomaly, my CMP, TSH, and vitamin D results were all within normal limits. Given this context, should I be concerned about experiencing any serious health issues? Thank you for your insights!

Thyroid DisordersInternal MedicineEndocrinology

Answers (1)

Cony

7/23/2025, 3:31:37 PM

OpenHealth AI

It's understandable to feel anxious about your lab results, especially given the low platelet count and the other symptoms you've mentioned. Let’s break down your situation to provide clarity and actionable next steps.

Summary of Key Points:

  1. Your low platelet count and slightly low MCHC are noted, but the remaining blood results are mostly normal.
  2. The symptoms you're experiencing, such as fatigue, bruising, and feeling cold, should be monitored.
  3. Your history of iron deficiency may contribute to your symptoms, even if your current iron panel appears normal.

Explanation:

Your platelet count of 137, although below the normal range, is only slightly so. A variety of factors can affect platelet levels, including recent infections like strep throat or medications (e.g., antibiotics). Your MCHC being low might indicate a mild concern regarding hemoglobin concentration but isn’t typically alarming by itself.

Frequent bruising can be caused by low platelet counts, and feelings of fatigue and being cold can be related to iron levels or a number of other reasons. It is good that your doctor suggested repeating the tests in two weeks, as this will help establish whether the low platelet count is persistent or not.

Actionable Next Steps:

  1. Monitor Symptoms:

    • Keep track of your bruising, fatigue, and any new symptoms in a journal. Note any changes in frequency or intensity. This will be helpful for your doctor during your next visit.
  2. Diet and Nutrition:

    • Focus on consuming iron-rich foods to support your health since your ferritin is at the lower end of normal. Incorporate foods like leafy greens, lean meats, beans, and fortified cereals.
    • Pair these with vitamin C-rich foods (like citrus fruits) to enhance iron absorption.
  3. Hydration:

    • Drink plenty of fluids, especially if you feel fatigued or cold. Dehydration can sometimes contribute to fatigue.
  4. Manage Anxiety:

    • Practice relaxation techniques such as deep breathing, meditation, or gentle exercises like yoga, which can help reduce anxiety while waiting for your next test.
  5. Follow Up with Your Doctor:

    • Stick to the plan of repeating the platelet count as advised, and bring up any new symptoms or concerns you may have since your last test.

It’s natural to feel anxious, but try to focus on the manageable aspects of your situation. It's a positive step that your doctor is monitoring your condition, and you’re taking an active role in your health. If symptoms worsen significantly, such as increased bruising or bleeding, please seek further advice. Let me know if you need any more information or support!

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