Persistent Cold Sores on My Wife’s Lips: Are They Herpes?
My wife, who is 23 years old and weighs 130 pounds, does not smoke, drink alcohol, or use drugs. After returning from our trip to Italy on June 17, she began experiencing discomfort on her upper lip. What started as mild dryness and some flakiness on the left side quickly escalated in severity. We initially assumed it was due to sun exposure or insufficient hydration, so she applied a combination of Aquaphor and Vaseline, but there was little improvement. A few days later, she decided to try a medicated lip balm, specifically Medi Balm with hydrocortisone, for a week. While it seemed to provide relief during its use, the symptoms returned almost immediately after she stopped applying it. Most recently, she experimented with Avene Cicalfate Lip Balm, only to wake up the next morning to find her lips covered in yellow crusting, white bumps, and a stinging sensation. It was the worst appearance she had seen thus far. Now, almost a month has gone by, and the affected area is still not healing as it should. We are both puzzled and concerned that this might be a case of HSV-1. I’ve kissed her numerous times since she first noticed the irritation, yet I haven’t experienced any symptoms on my lips. We appreciate any insights or advice you can offer regarding this situation.
Answers (1)

7/18/2025, 2:50:47 PM
OpenHealth AI
It sounds like your wife has been dealing with a frustrating and uncomfortable situation on her lips. The symptoms—such as dryness, flakiness, crusting, and stinging—can indeed raise concerns about conditions like cold sores caused by the herpes simplex virus (HSV-1). However, these symptoms can also result from other causes such as contact dermatitis, allergic reactions, or sun damage.
Main Points:
- The symptoms your wife is experiencing could be related to HSV-1, but they may also indicate other skin irritations.
- Since her condition has persisted and worsened despite treatment, it is important to consider a targeted approach for soothing and healing her lips.
Explanation:
- Cold Sores (HSV-1): These can manifest as painful blisters, typically accompanied by crusting and discomfort. If this is the case, the lesions usually heal in about 7 to 10 days. However, recurrence is common.
- Contact Dermatitis: With the use of various lip products and the history of symptoms following sun exposure, it's possible she is experiencing a reaction to an ingredient in those products or simply sensitivity exacerbated by environmental factors.
- Management Steps: Since conventional treatments haven’t provided lasting relief, a more structured approach might be needed.
Next Steps:
-
Identify Products: Ensure that none of the lip balms or products contain potential irritants or allergens. Consider avoiding heavily flavored or medicated products for a while.
-
Simplify Care: Use a plain, unscented lip balm (like plain petroleum jelly) to protect the area, avoiding irritation from other products.
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Cool Compresses: Applying a cool, damp cloth to the affected area can provide immediate relief and may help reduce inflammation.
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Monitor Symptoms: Keep track of any changes in the area, such as new lesions, itchiness, or an increase in redness.
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Sun Protection: Apply lip balm with sunblock to protect her lips from further sun exposure, especially since she recently came back from a trip.
If her symptoms do not improve in a week or worsen (like developing fever blisters or severe pain), it may be beneficial to seek professional advice for a more clear diagnosis and treatment plan. In case it is HSV-1, antiviral medication might be prescribed to help manage future outbreaks.
Take care, and I hope to hear soon about her progress!
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