Seeking Clarity on MIL's Health Crisis
My mother-in-law, aged 63 and approximately 5'3" tall with a weight of around 130 pounds, has always been notably active and has a clean health record—she doesn’t smoke and abstains from alcohol. Unfortunately, she was admitted to the hospital on Tuesday. In early 2025, she experienced a serious decline in her health. She became bedridden, suffered from severe dehydration, and experienced constant pain. Doctors diagnosed her with a thyroid issue, leading to significant physical therapy sessions to restore her mobility. This past weekend, her condition worsened. She began to develop extensive bruising and was in extreme discomfort. After visiting her doctor on Monday, blood tests were performed. On Tuesday, the concerning news arrived; her blood platelet levels were dangerously low, prompting immediate hospitalization. As of today, her platelet count remains low, and her LDH levels have risen sharply. Medical professionals have conducted full-body scans and additional tests. My father-in-law spoke with my husband, conveying that the doctors suspect an autoimmune disorder that is destroying her platelets. They have cautioned against administering additional platelets, as this could potentially exacerbate the situation. Some treatment options were discussed which may help bring about remission, but they also carry a significant risk of mortality. Tomorrow, a biopsy is scheduled to further investigate her condition, although the specifics are still unclear. Coupled with these developments, her platelet count has recently dropped again, now below 22, and her LDH is above 900, leading the medical team to consider an IVIG treatment. I am reaching out to see if anyone can provide insights regarding her situation or possible conditions. Regrettably, my father-in-law was overwhelmed during his conversation with the doctors and has little recollection of the details that were shared with him. While we remain hopeful, uncertainty weighs heavily on us. It appears as though she is losing her will to fight, despite our encouragement to keep persevering. This year has already dealt us painful losses—my father, grandmother, and a beloved pet—and the thought of losing her too feels unimaginable.
Answers (1)

7/18/2025, 3:30:59 AM
OpenHealth AI
I’m truly sorry to hear about your mother-in-law’s health crisis, and it's completely understandable to feel overwhelmed by the uncertainty. It's important to remember that you're not alone in this. I will provide some insights into her situation and suggest ways you can support her and your family during this challenging time.
Main Points:
- Your mother-in-law's low platelet count and high LDH levels suggest possible autoimmune involvement.
- The upcoming biopsy will provide crucial information for diagnosis and treatment options.
- Emotional support for her and the family is vital during this tough period.
Explanation:
Low platelet counts (thrombocytopenia) can result from various conditions, including autoimmune disorders such as immune thrombocytopenic purpura (ITP), lupus, or other underlying issues. The fact that she is experiencing severe bruising and pain, alongside the lab results, supports the concern for an autoimmune disorder that may be attacking her platelets.
The rising LDH indicates cell breakdown, which can occur with various medical conditions, including hemolysis (destruction of blood cells), possibly linked to her thyroid issue or a new autoimmune process.
Next Steps:
- Prepare for the Biopsy: Ensure any questions about the procedure or potential outcomes are noted for discussion with the doctors post-biopsy. Understanding the purpose of the biopsy can ease some anxiety.
- Support Her Emotionally: Encourage her to express feelings, and let her know that it’s okay to feel scared or frustrated. Sometimes, just being there for her can make a significant difference.
- Educate Together: Consider researching autoimmune disorders together, which may give both your mother-in-law and your family a sense of empowerment regarding her condition.
- Monitor Significantly: Keep an eye on her symptoms and communicate any changes to her medical team. If she seems to be losing hope, try to find small aspects of her health or comfort that can be reinforced positively.
Final Thoughts:
This is an incredibly challenging time, both physically for your mother-in-law and emotionally for your family. Each new piece of information will help guide her treatment options moving forward. Remain hopeful, and focus on the support you can give as a family. If you have any further questions or need more specific details about any terms or conditions, feel free to reach out. Your care and support are invaluable during such an uncertain period.
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