Epidermoid Cyst Update
Key Details: F33. Generally in good health. Currently 31 weeks into my pregnancy. I have developed an epidermoid inclusion cyst. Initially, it was the size of a pea on Thursday, ballooning to the size of a marble by Friday, at which point it appeared inflamed and prompted treatment from my dermatologist who administered an injection. By Monday, the cyst had expanded to roughly the size of a golf ball and had become quite painful, leading her to prescribe Cephalexin 500mg to be taken once daily. After being on antibiotics for 24 hours, I have noticed a change in the cyst; it has shifted from being deeply embedded under the skin to protruding more visibly on the skin's surface. Although it is still clearly defined, its position is now more pronounced. Could this alteration indicate healing, or is there a possibility that it could be evolving into an abscess requiring drainage? Should I seek a second opinion regarding this condition?
Answers (1)

7/15/2025, 4:20:40 PM
OpenHealth AI
It sounds like you're understandably concerned about the rapid changes to your epidermoid cyst, especially during your pregnancy. Based on what you've described, there are a few key points to consider.
Main Points:
- Change in Appearance: The alteration in the cyst's position suggests a response to treatment, but ongoing monitoring is essential.
- Antibiotics Role: The cephalexin may be helping to reduce any underlying infection, which can impact the cyst's behavior.
- Next Steps: It's important to monitor symptoms closely and consider follow-up if there are any signs of worsening.
Explanation:
Epidermoid cysts can become inflamed or infected, which might be why yours has grown and become painful. The change from being deeply embedded to more pronounced on the surface can happen as the cyst responds to inflammation or treatment.
While this change might indicate healing, it's important to watch for potential signs of complications, such as pus formation or increased redness and swelling around the cyst. If the cyst were to evolve into an abscess, it could require drainage, which would be more critical than if it remains a simple cyst.
Next Steps:
- Continue Monitoring: Keep an eye on the cyst for any redness, increased tenderness, drainage of pus, or worsening pain.
- Hydration and Rest: Focus on staying hydrated and getting adequate rest, which are important during pregnancy.
- Track Changes: Document any changes or symptoms you experience in the next 48-72 hours — this will help identify trends and will be useful for your healthcare provider.
- Follow-Up Care: If the cyst grows larger, becomes more painful, shows signs of infection, or you have concerns, it would be a good idea to reach out to your dermatologist for a follow-up or consider a second opinion if you're unsure about your current care plan.
Be sure to communicate all your symptoms and concerns clearly to your healthcare provider, especially because of your pregnancy. Take care!
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