OpenHealth Q&A

Get answered by medical professionals

Understanding Hyperkeratosis and Parakeratosis on Pap Smear Results

7/14/2025, 3:10:18 PMMale25-34

As a 28-year-old woman standing at 5'1" who does not smoke and is currently not engaged in any sexual activity, I am not on any medication. I have previously undergone one Pap smear but found the recent results somewhat confusing. Below are the details of my test findings: CYTOLOGICAL DIAGNOSIS: The specimen is adequate for assessment and includes the endocervical component. INTERPRETATION: No intraepithelial lesion or malignancy detected; however, hyperkeratosis and parakeratosis are present.

Internal MedicineEndocrinologyRheumatology

Answers (1)

Cony

7/14/2025, 3:10:34 PM

OpenHealth AI

The presence of hyperkeratosis and parakeratosis in your Pap smear results indicates that there are some changes in the cells of your cervix, but it is reassuring to note that no intraepithelial lesions or malignancies have been detected.

What Hyperkeratosis and Parakeratosis Mean:

  • Hyperkeratosis is a thickening of the outer layer of skin or mucous membranes. In the cervix, it can occur due to irritation, infection, or friction.
  • Parakeratosis refers to the retention of nuclei in keratinized cells, which can be seen in various conditions, including irritation or inflammation.

These changes can be caused by factors such as hormonal fluctuations, infections, or even irritation from sexual activity, but since you mentioned you are currently not sexually active, it could be due to other benign reasons.

Next Steps:

  1. Monitor Symptoms: Keep an eye on any unusual symptoms such as unusual discharge, pain, or irregular bleeding over the next few months.

  2. Stay Informed: Educate yourself about cervical health. Knowing the signs of changes in your body can help you recognize if any follow-up might be necessary.

  3. Follow-up Screening: Discuss with your healthcare provider when your next Pap smear should be scheduled—generally, it’s recommended every 3 years if previous results have been normal.

  4. Lifestyle Considerations: Incorporate a balanced diet, regular exercise, and adequate hydration into your routine to support overall health and potentially improve your cervical health.

This finding might seem a bit concerning, but it’s important to remember that your results are largely normal. If you feel uncertain or worried, don’t hesitate to reach out to your healthcare provider for clarity or to discuss further options.

Related Questions

Understanding Post-Surgical Pain After Ganglion Cyst Removal

I’m 17 years old (female, though I prefer He/him pronouns) and I have Ehlers-Danlos Syndrome (EDS) along with Dysautonomia. Currently, I’m not taking any medications that might impact my situation apart from an SNRI and birth control to manage cramping. Around a month ago, I underwent surgery to remove a ganglion cyst located on my dominant wrist (the right one). This cyst had been present for roughly three years, and despite my doctor attempting to aspirate it, the procedure was unsuccessful due to its firmness, leading to surgical intervention. This cyst significantly limited my wrist mobility. Now, after approximately four weeks post-surgery, I can say that my wrist is mostly improved. The scar is healing fairly well, and I’ve regained about half of my wrist’s mobility compared to the left one. Yet, I still experience significant pain when I move or apply pressure on the area that housed the cyst. Is this pain considered normal? Additionally, my fingers are in constant discomfort, and my wrist seems to dislocate frequently. Due to my EDS, I am accustomed to joint pain and dislocations, but this particular pain feels more severe than what I usually endure. When I brought this up with my surgeon, he dismissed my concerns, stating that such dislocations are common for individuals my age. However, I experience dislocations at least twice daily, and the process of resetting them creates such a loud sound that I've been asked to leave classes to avoid disturbing others. Is this normal? Could it be related to the cyst? Moreover, about four days ago, I noticed a small lump forming on my wrist just above the surgical area. When I consulted my doctor about it, he informed me that it was a benign fatty tumor and assured me it wasn't a serious issue. However, I've never encountered anything like this before, and while the lump is not painful, soft, and relatively small, I’m puzzled about its sudden appearance. Why did this occur, and what could explain my doctor’s nonchalant attitude towards my symptoms? I understand that experiencing pain and limited mobility after surgery is not unusual, but given my doctor’s dismissive approach towards my concerns, I felt compelled to seek insight here as well. He often seems skeptical about the symptoms I report, making it difficult for me to fully trust his evaluations.

ArthritisLupusRheumatology
Male25-34
37 minutes ago

Concerns About Changes in Partner's Semen Consistency

At 19 years old, I’m seeking some insights regarding a situation. My girlfriend, who is also 19, has experienced a noteworthy change in her semen consistency during our intimate encounters over the last two to three weeks. To provide some background, she stands at 5 feet 5.5 inches tall and weighs approximately 130 pounds. Her ethnicity is Caucasian, and she is from Canada. Historically, my girlfriend has been in good health without any significant medical conditions. Currently, she is not taking any medications. Previously, she had a history of frequent vaping, but that was about a year ago, and now she limits it to occasional use. The change in her semen is quite striking; it appears very thick, white, and somewhat chunky, rather than being mostly liquid. There are some liquid components, but the thick texture predominates. Throughout this period, she has maintained her regular diet, and importantly, there are no signs of a urinary tract infection or sexually transmitted disease. Neither does she experience any pain or unusual odors. This alteration has raised some concerns for her, and while I am trying to be supportive, I am uncertain about the potential causes. We searched online for explanations, but the reactions we found mostly related to digital sources that discussed various infections or medical conditions, none of which seemed to match her symptoms. Does anyone have insights or similar experiences regarding this matter? It would be appreciated in easing her worries and determining the best course of action.

ArthritisEndocrinologyRheumatology
Male25-34
1 hour ago

Three Weeks Post Gallbladder Surgery - Is It Infected?

Patient Profile: - Age: 35 - Gender: Female - Height: 5 feet 4 inches - Weight: 160 pounds - Ethnicity: Asian Issue Duration: 3 weeks Location: United States Relevant Medical History: Approximately three weeks ago, I underwent gallbladder removal surgery. Recently, I have observed a slight amount of cloudy fluid emerging from the surgical site over the past few days. Just moments ago, I noticed a possible pus discharge from the incision. While there is no significant pain, I do feel mild soreness when shifting my position. I have not experienced any fever or chills, and there is no unpleasant odor coming from the wound. Should I continue to clean the area with soap and water, or would it be prudent to seek immediate medical attention at the ER for a professional evaluation?

Internal MedicineEndocrinologyRheumatology
Male25-34
1 hour ago

Should I Seek Medical Attention?

At 22 years old, I am a female who has been on medications like duloxetine, lamotrigine, and hydroxyzine for several years. I have managed to keep my Graves' disease under control, but I have reasons to believe I may also be experiencing symptoms of POTS (Postural Orthostatic Tachycardia Syndrome). Last year, I was scheduled to consult a neurologist regarding hand tremors and the possibility of fibromyalgia. Unfortunately, I could not continue my treatment after relocating and losing my health insurance. Just 15 minutes ago, I fainted. Prior to that incident, I was feeling unwell—dizzy, my vision was blurry, and I experienced a whooshing sensation along with heat in my ears. My face and arms also felt tingly. After fainting, I experienced a heavy, aching sensation in my head, and I still have a headache now. Additionally, I’ve been waking up with headaches for a couple of days. I want to know if it's advisable to go to the emergency room. It's important to note that this isn’t my first fainting spell; I had one incident years back, which helped me recognize the signs when it started happening. At that time, I was lifting a heavy bed frame, and when I began to feel faint, I tried to sit down but stood back up to assist, and that’s when I lost consciousness. I’m unsure how long I was out, but I initially thought I was just sleeping before realizing what had happened when I regained awareness.

LupusThyroid DisordersInternal Medicine
Male25-34
1 hour ago

Seeking Guidance for My Mother's Sudden Hearing Loss Case

I am looking for advice regarding my mother's situation with sudden sensorineural hearing loss (SSNHL). **Patient Overview:** - **Age:** 48 years - **Gender:** Female - **Medical Issues:** Hypothyroidism and overweight (approximately 95 kg at the onset) - **Treatment:** Thyroid medication (25 mcg taken daily) **Medical Background:** In November 2025, my mother experienced an abrupt hearing loss in her right ear accompanied by dizziness and nausea. We consulted several ENT specialists within approximately 36 hours following the onset of her symptoms. She received a diagnosis of SSNHL but unfortunately, she did not undergo intratympanic steroid injections during the critical first 24 hours that could have aided her recovery. Despite receiving subsequent treatment, she has not regained hearing in her affected ear. **Examination Results:** - **Audiogram:** Loss of approximately 100 dB in the right ear; left ear shows normal hearing. - **Brain MRI:** A normal scan was conducted previously, ruling out tumors. - **Laboratory Tests:** Recent blood tests (including thyroid function, HbA1c, renal and liver function tests, CBC, etc.) show elevated TSH (6.73) and a HbA1c of 8.5%. We are currently preparing for a contrast MRI to eliminate the possibility of a vestibular schwannoma or nerve issues. **Current Condition:** The hearing loss persists in her right ear. She is feeling anxious about the upcoming contrast MRI, which involves gadolinium injection. However, she has started making positive lifestyle changes and has lost about 4.5 kg over the past two months, adhering to a protein-rich diet and a walking regimen. **My Inquiries:** 1. Is it still beneficial to perform a contrast MRI several months after the initial SSNHL diagnosis, considering that a normal MRI has already been completed? 2. For cases such as this—severe SSNHL with delayed steroid intervention—are there realistic prospects for hearing recovery at a later date? 3. Are there any additional tests or treatments that should be taken into account at this stage? 4. For family gatherings where loud music will be present, would high-quality earplugs or noise-canceling earbuds be a good option to safeguard her healthier ear? 5. Is it advisable for her to continue with whey protein supplementation and the weight-loss plan? 6. What should we prioritize for long-term management: hearing aids, rehabilitation, regular monitoring, etc.? I recognize that the chances of recovery may be slim, but I want to ensure we are covering all bases and that her care plan is appropriate. I appreciate any insights or suggestions you can offer. Thank you for your assistance!

Thyroid DisordersEndocrinologyRheumatology
Male25-34
2 hours ago